Vascepa (
generic name: ethyl eicosapentaenoic acid) is a drug derived from omega-3 fatty acids, specifically eicosapentaenoic acid (EPA), found in fish oil. It is prescribed primarily to lower high triglyceride levels in adults with severe hypertriglyceridemia.
Vascepa belongs to a class of drugs known as lipid-lowering agents. This medication works by reducing the production and increasing the clearance of
triglycerides from the bloodstream, thus aiding in the prevention of cardiovascular complications.
In addition to its lipid-lowering effects, Vascepa has been shown to provide cardiovascular benefits in patients at high risk for heart disease or stroke. Its mechanism is not entirely dependent on triglyceride reduction; it also exhibits anti-inflammatory and plaque-stabilizing properties. For more detailed medical information, visit theÂ
Mayo Clinic web page.
Dosage
It is essential to follow the instructions from the prescribing healthcare provider and in the patient information leaflet. The recommended dosage of Vascepa is 4 grams per day, taken as two 1-gram capsules twice daily with food. It is important to take the medication consistently to achieve optimal results. If a dose is missed, it should be taken as soon as possible unless it is close to the time for the next dose. In such cases, the missed dose should be skipped, and the regular schedule should be resumed. Do no double-dose to make up for a missed dose.
Storage
Vascepa should be stored at room temperature, typically 20°-25°C (68°-77°F). It should be kept in its original container, away from direct sunlight and moisture.
For more information, read our article on drug storage.
Frequently Asked Questions About Vascepa
Can Vascepa replace statins?
No, Vascepa is not a replacement for statins. It is often prescribed alongside statins to enhance cardiovascular protection.
Does Vascepa cause weight gain?
Vascepa is not associated with weight gain. Its effects are specific to lipid levels and cardiovascular health.
Are there any dietary restrictions while taking ethyl eicosapentaenoic acid?
A heart-healthy diet is recommended. Avoid high-fat or high-cholesterol foods to maximize the drug’s benefits.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.Â
Read the information leaflet that comes with the medication.
If a sudden allergic reaction (anaphylaxis) occurs after taking Vascepa, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.
Most people who use Vascepa do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.
Some of the side effects that have been reported include joint pain, gastrointestinal discomfort, and swelling in the extremities
Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.
Vascepa is FDA-approved for treating severe hypertriglyceridemia, a condition characterized by blood triglyceride levels exceeding 500 mg/dL. Symptoms include abdominal pain, pancreatitis, and fatty deposits in the skin. Vascepa is also used as an adjunct to diet in patients with cardiovascular risk factors to reduce the likelihood of major events such as heart attack, stroke, and coronary revascularization.
Emerging research suggests its potential off-label use in managing metabolic syndrome, marked by obesity, insulin resistance, and high blood pressure, though further studies are needed.