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  • US Name:

    Sulfazine

  • Alternative Names:

    Salazopyrin, Salazopyrin En

  • Active Ingredients:

    Sulphasalazine

  • Brand Manufacturer:

    Pfizer

  • Manufacturer Location:

    Sweden

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Sulfazine *

Prescription Required
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Sulfazine is an anti-inflammatory drug that treats Crohn’s, colitis, and arthritis. It is also used for inflammatory skin ulcers.

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Salazopyrin Brand 500mg
100 Tablets
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Our price:
$29.00
Salazopyrin En Brand 500mg
100 Tablets
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Our price:
$36.00

*Please note all prices are in US dollars
Sulfazine/ Salazopyrin (generic name: sulfasalazine) is a medication for inflammatory bowel diseases (IBD) such as Crohn’s disease and ulcerative colitis. Salazopyrin EN can be prescribed for rheumatoid arthritis. Sulfasalazine belongs to a group of anti-inflammatory drugs called aminosalicylic acid types. These medications are also sometimes used to treat skin ulcers like pyoderma gangrenosum. Sulfasalazine’s ability to control the immune system, reduce inflammation, and inhibit the growth of some cells makes it a possible treatment for various skin conditions. Because of these effects, doctors can prescribe this Salazopyrin EN off-label if they believe that the medicine is appropriate for a patient’s skin issues, such as alopecia areata (patchy hair loss), psoriasis, psoriatic arthritis, lichen planus, and pemphigus.

Dosage

Always use the preparation as instructed by the doctor. Patients who are unsure about the treatment regimen or dosage should consult their pharmacist or doctor. This medicine should be swallowed whole with a glass of water and not be chewed, split, or crushed as the tablets are film-coated. Drink sufficient fluids while taking the medicine to avoid kidney problems.

Caution

If an intact Sulfazine tablet passes through in the stool, contact a doctor, as the active ingredient may not have been absorbed.

FAQ

How long can you safely stay on sulfasalazine?
Sulfasalazine is usually okay for long-term use. A doctor may check kidney function before and during the treatment. In some rare situations, sulfasalazine might lead to kidney issues.
When should I stop taking sulfazine?
Sticking to the treatment plan is important, even if feeling better. Avoid stopping medication without talking to a doctor first.
What vitamins should I take with sulfasalazine?
Sulfazine can reduce the body’s absorption of folic acid (vitamin B-9). Therefore, a doctor might suggest taking a folic acid supplement.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Read the information leaflet that comes with the medication.

If after taking Sulfazine, a sudden allergic reaction (anaphylaxis) occurs, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

If a rash develops with blistering that affects the tongue and mouth, it could be a sign of Stevens-Johnson syndrome or toxic epidermal necrolysis (TEN). A rash on the upper face (cheeks and nose bridge) can also occur. In these cases, report immediately to the doctor.

Most people who use Sulfazine do not experience any negative side effects. Doctors prescribe Sulfazine because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include heartburn, indigestion, and nausea.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

 

Salazopyrin is indicated for the treatment of inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, and Salazopyrin EN can also be used for IBD and rheumatoid arthritis. 

Crohn’s Disease: Common signs and symptoms of Crohn’s disease include abdominal pain, blood in the stool, nausea, vomiting, prolonged diarrhea, unexplained weight loss, and fever. 

Ulcerative Colitis: Symptoms of ulcerative colitis can vary depending on how bad and where the inflammation is. Some usual signs are diarrhea (sometimes with blood or pus), bleeding from the bottom, abdominal pain and cramps, pain in the rectum, feeling like you urgently need to go to the bathroom but not being able to, losing weight, feeling tired, and having a fever.

Rheumatoid Arthritis (Salazopyrin EN only): Symptoms of rheumatoid arthritis can include tender, warm, and swollen joints, along with stiffness that is often more pronounced in the mornings and after periods of inactivity. Other signs may involve fatigue, fever, and a decrease in appetite.

  • Is sulfasalazine an antibiotic?
    Sulfasalazine is partially an antibiotic. Normal bacteria in the gut break it down into two components: one is a sulfonamide antibiotic that kills harmful bacteria, and the other helps reduce inflammation and control an overactive immune system.
  • Can ulcerative colitis be cured?
    Ulcerative colitis cannot be completely cured, but effective treatments such as sulfasalazine do provide significant symptom relief.
  • What does rheumatoid arthritis pain feel like?
    Rheumatoid arthritis pain often feels like a throbbing or aching sensation in the joints. This pain is usually more intense in the morning or after periods of inactivity.

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