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  • US Name:

    Orudis

  • Generic Names:

    Bi-Profenid, Pentalgin

  • Active Ingredients:

    Ketoprofen

  • Brand Manufacturer:

    Sanofi

  • Manufacturer Location:

    Turkey

  • Click here to view Product Insert

Orudis

Prescription Required

Orudis capsules are prescribed to relieve pain, swelling, fever, and inflammation in some forms of arthritis, gout, and dysmenorrhea.

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Bi-Profenid Brand 150mg
10 Tablets
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Our price: $13.50

*Please note all prices are in US dollars
Orudis (generic name: ketoprofen) is a prescribed medication. The tablets can be taken to relieve pain, swelling, fever, and inflammation in chronic conditions such as rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, gout and dysmenorrhea (menstrual pain ). It can also be prescribed for the treatment of acute sudden-onset musculoskeletal or postoperative pain.  Orudis is a nonsteroidal anti-inflammatory drug (NSAID) used for its anti-inflammatory, analgesic, and antipyretic properties. The controlled-release tablets contain a total of 150 mg of ketoprofen in two interlocking layers of 75 mg of immediate-release and 75 mg modified-release ketoprofen. This allows for more sustained symptom control and lower dosages than only immediate-release forms of ketoprofen.  Orudis controlled-release is considered a preferred choice for patients requiring long-term treatment. It has demonstrated greater efficacy and tolerability, even in older patients.

Dosage

Orudis is a prescription form of ketoprofen; the physician will determine the dosage based on the patient’s age, weight, and symptoms.  The typical dosage is one tablet daily taken with or after meals. It should be taken with a glass of water without splitting or breaking it. If a dose is missed, it can be taken up to six hours before the next scheduled dose, but missed doses should not be made up by double-dosing.

This information is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Before using this medication, read the manufacturer’s Product Insert. Not all side effects can be listed here. Consult a healthcare provider if you experience these or other unexpected side effects.

Orudis can cause side effects similar to those of other NSAIDs, and the side effects generally do not vary significantly based on the condition being treated. Individual patient factors like age, overall health, and concomitant medications can influence the severity and likelihood of these side effects.

The most common side effects include:

  • Stomach pain, heartburn, nausea, and gastrointestinal bleeding. NSAIDs can irritate the stomach lining, leading to ulcers and bleeding.
  • Cardiovascular risks, especially with long-term use, include increased blood pressure, heart attack, and stroke.
  • Kidney damage or failure, particularly in patients with pre-existing kidney conditions or in elderly patients.
  • Allergic reactions causing mild skin rashes
  • Central nervous system (CNS) effects can include dizziness, headache, and tinnitus (ringing in the ears).

It is essential to consult with a healthcare provider to understand the specific risks associated with Orudis based on personal health history and the condition being treated.

In rare cases, there is a possibility of anaphylactic shock. The reactions within a short time after starting treatment with Orudis may include: 

  • Shortness of breath
  • Trouble with breathing
  • Swelling of the face or throat
  • Chest pain
  • Weakness in one part or on the side of the body
  • Slurred speech 
  • Vomiting blood, severe stomach pains, or dark stools
  • Skin reactions include hives, burning or tingling (paresthesia), itching, easy bruising, prolonged bleeding after breaking the skin, or flushed or pale skin.

If any of these are observed, stop taking the medication immediately and go to an emergency healthcare facility. Tell them that you have just started taking Orudis.

Warnings:

NSAIDs may cause side effects such as dizziness, drowsiness, weakness, and visual impairment. If you experience these side effects, do not drive any vehicle or use tools or machinery.

Orudis can be prescribed for the following conditions:

  • Rheumatoid arthritis – a condition where inflammation is a key component of pain and joint stiffness.
  • Ankylosing Spondylitis – a type of inflammatory arthritis that mainly affects the spine and sacroiliac joints. Orudis helps by reducing the pain and inflammation in these areas, promoting better spinal flexibility and function.
  • Osteoarthritis – a condition where inflammation of the joints leads to pain and discomfort.
  • Dysmenorrhea – a common gynecological condition when there are painful cramps at the time of menstruation. Contractions during menstruation can cause pain. Prostaglandins play a role in these contractions and can make them more painful. By reducing prostaglandin levels, Orudis helps alleviate this pain. It also has anti-inflammatory properties and can help to lessen menstrual cramps that can come from inflammation in the pelvic area.

Orudis can also be prescribed alongside other medications as part of a comprehensive treatment plan for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

  • How do NSAIDs work for dysmenorrhea?
    Orudis (ketoprofen) is a form of nonsteroidal anti-inflammatory drug (NSAID). It is believed that NSAIDs relieve dysmenorrhoea mainly by suppressing the production of endometrial prostaglandins in the walls of the uterus during menstruation. This alleviates cramps and restores regular uterine activity. It also provides direct analgesic action on the central nervous system and helps relieve pain.
  • How long does it take for Orudis to work?
    The Orudis controlled-release capsule can take 2 to 3 hours after it is taken before it starts to kick in. Usually, it only needs to be taken once daily, but doctors can vary the dosage according to a patient's condition.
  • What do NSAIDs do for ankylosing spondylitis?
    Orudis is one of the nonsteroidal anti-inflammatory drugs (NSAIDs) that are the first-line treatment of ankylosing spondylitis (AS). It has rapid effects on the inflammatory symptoms of AS.

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