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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Orencia works by interfering with one of the activation steps of immune T-cells, helping to reduce attacks of rheumatoid arthritis, psoriatic arthritis and juvenile idiopathic arthritis.
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| Orencia Brand | 125mg 4 Pre-Filled Syringe |
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Our price: $1,220.00 |
Orencia (generic name: abatacept) can be prescribed to treat moderate to severe immune-driven joint and autoimmune conditions. It belongs to the pharmacological class of selective T-cell costimulation modulators, which act by disrupting part of the immune system that contributes to chronic inflammation in diseases such as rheumatoid arthritis(RA), psoriatic arthritis (PsA) and polyarticular juvenile idiopathic arthritis (pJIA).
Abatacept is a biologic medicine that works by binding to the immune-cell proteins CD80 and CD86, thereby preventing T-cells from receiving a key activation signal. This mechanism helps reduce the ongoing immune attack on joints and other tissues.
By reducing inflammation, Orencia helps ease symptoms such as joint swelling, persistent pain, and functional limitations. In many patients with moderate to severe disease who have not gained sufficient benefit from other treatments, this therapy offers an additional option to help stabilise their condition and support daily activities. It’s intended for longer-term management, rather than short-term relief only.
It is important to follow the dosage instructions printed on the label of the box. Check with a doctor or pharmacist if there are any doubts regarding the proper dosage and treatment regimen.
Orencia is administered either as an intravenous infusion or a subcutaneous injection, depending on patient age and formulation. For adult rheumatoid arthritis, dosing typically begins with a loading intravenous infusion followed by regular maintenance dosing, or direct weekly subcutaneous injections of 125 mg.
The intravenous form is given as a dose depending on body weight, then repeated at specified intervals, transitioning to the subcutaneous form if needed.
For subcutaneous injection, the dose is usually once weekly; patients should use the same day each week for consistency.
If a dose is missed, it should be taken as soon as possible or at the next scheduled time. Do not take two doses at once to make up for the missed one.
After symptoms are well controlled, the doctor may adjust the regimen to the lowest effective dose and reassess periodically.
Store in the refrigerator at 36-46°F (2°-8°C) in its original package. Protect from light. Do not freeze..
Protect from humidity, freezing temperatures and excessive heat.
Keep the medicine in its original container (or pre-filled syringe/pen) until use, if applicable.
Keep out of reach of children.
Do not use the product beyond the expiry date shown.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.
The patient information leaflet that comes with the medication includes full information about the correct usage, storage and possible side effects. Be sure to read and understand these, and if there are any questions, discuss these with a healthcare provider or pharmacist before starting treatment.
Most people who use Orencia do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.
Caution:
If a sudden allergic reaction (anaphylaxis) occurs shortly after taking Orencia, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.
Common side effects:
upper respiratory infections (such as a cold or sore throat)
headache
nausea
injection-site reactions (for the subcutaneous form)
cough or bronchitis
Serious side effects requiring immediate action:
serious infections (for example tuberculosis, pneumonia, or opportunistic infections)
possible increased risk of certain types of cancer (in patients with risk factors)
worsening of chronic obstructive pulmonary disease (in patients who already have it)
vaccine-related reactions or reduced vaccine effectiveness (because of immune modulation)
Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.
Orencia is prescribed for a range of immune-mediated joint conditions including:
joint swelling (often in hands, wrists, or feet)
persistent pain and tenderness in the joints
morning stiffness lasting more than 30 minutes
possible reduced ability to perform everyday tasks
RA is a disease in which the immune system attacks the lining of joints, causing ongoing inflammation, damage and functional loss. Orencia works to reduce this immune activity and support joint health. orencia.com+1
joint pain and swelling, sometimes in fingers or toes (sausage-like appearance)
stiffness, especially after resting
skin changes (psoriasis) in conjunction with joint symptoms
In PsA, the immune system drives inflammation in skin and joints. Orencia helps reduce both joint and skin manifestations.
young children or adolescents aged 2 years and older experiencing joint pain and swelling in five or more joints
stiffness, possibly affecting mobility or school activities
signs of inflammation over time
Orencia is used in children aged 2 years and older for this condition, either alone or with methotrexate.
In each condition, the aim is to reduce disease activity, prevent joint damage, and support function and quality of life over the long term. The decision to use Orencia should be guided by a specialist who assesses disease severity, prior treatments, and overall health status.
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