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For visual reference only; actual product may vary

  • US Name:

    Onfi

  • Alternative Names:

    Frisium

  • Active Ingredients:

    Clobazam

  • Brand Manufacturer:

    Sanofi-Aventis

  • Manufacturer Location:

    France

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  • Click here to view Product Insert

Onfi *

For visual reference only; actual product may vary

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Onfi (Clobazam) is a benzodiazepine medication used as an adjunctive therapy to control seizures in patients with Lennox-Gastaut syndrome (LGS). It is suitable for adults and children aged two and older. Onfi works by calming brain activity to help reduce the frequency of seizures.

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Frisium Brand 10mg
30 Tablets
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*Please note all prices are in US dollars

What is Onfi?

Onfi is a prescription benzodiazepine medication with the active ingredient clobazam. It is used in combination with other medicines to treat seizures associated with a severe form of epilepsy called Lennox-Gastaut syndrome (LGS). This condition causes multiple types of seizures and typically begins in early childhood. Onfi is approved for use in adults and children who are two years of age or older. It helps to reduce the number of seizures patients experience. The medication is taken orally and is part of a comprehensive treatment plan.

How does Onfi work?

Onfi works by enhancing the effect of a natural chemical in the brain called gamma-aminobutyric acid (GABA). GABA is an inhibitory neurotransmitter. It blocks certain signals in the brain and reduces the activity of nerve cells. Clobazam, the active ingredient in Onfi, binds to GABA-A receptors. This action increases GABA’s calming effects on the brain. By slowing down excessive electrical activity, Onfi helps prevent the abnormal signaling that leads to seizures. This mechanism helps stabilize brain activity and control seizures.

Who is Onfi for?

Onfi is prescribed for patients diagnosed with Lennox-Gastaut syndrome who need additional help managing their seizures. It is an adjunctive therapy. This means it is used alongside other antiepileptic drugs. The medication is intended for adults and children aged two and above. It is a suitable option when a primary medication regimen does not provide adequate seizure control. A doctor evaluates the patient’s condition and medical history. This ensures Onfi is an appropriate and safe choice for them.

Dosage and administration

Onfi dosage is carefully tailored to each individual by their doctor based on weight and tolerability. It is typically taken once or twice daily, with or without food. The treatment usually begins with a low dose. The doctor will then gradually increase it over several weeks. This approach helps minimize potential side effects. Onfi is available as tablets or an oral suspension. Tablets may be swallowed whole or crushed and mixed with applesauce for easier administration. You should not stop taking Onfi suddenly, as this can lead to withdrawal symptoms and increased seizures. Your doctor will provide a tapering schedule if the medication needs to be discontinued.

Side effects

Onfi may cause side effects, which can range from mild to severe. Common side effects include drowsiness, fatigue, and dizziness. Some people may also experience fever, drooling, constipation, or changes in appetite. These effects are often most noticeable when starting the medication. More serious side effects require immediate medical attention. These include severe skin reactions, breathing problems, and unusual changes in mood like suicidal thoughts or worsening depression. It is important to discuss any side effects with your healthcare provider.

Why buy from IsraelPharm?

IsraelPharm offers a reliable and cost-effective way to purchase your essential medications like Onfi. We are a licensed pharmacy dedicated to providing safe, authentic brand-name drugs from trusted manufacturers. Our prices are often significantly lower than what you would find at local pharmacies, helping you save on treatment costs. We provide discreet, direct-to-your-door shipping for ultimate convenience. Our professional team is committed to high standards of customer service. You can feel confident managing your health with our secure and accessible online services.

Common side effects may include:

  • Drowsiness or sedation
  • Drooling
  • Constipation
  • Fever or cough
  • Fatigue and lethargy
  • Vomiting

Seek immediate medical attention for serious side effects, such as:

  • Severe skin rash (e.g., Stevens-Johnson syndrome)
  • Thoughts of suicide or worsening depression
  • Shallow breathing
  • Unusual changes in mood or behavior

Onfi is indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients 2 years of age or older.

  • Manages seizures in Lennox-Gastaut syndrome
  • Used with other antiepileptic medications
  • Suitable for adults and children over two years old

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