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    Bempedoic Acid/Ezetimibe

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Nustendi is prescribed together with a low-fat diet to control cholesterol levels

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Nustendi Brand 180/10mg
28 Tablets
Our price: $155.00

*Please note all prices are in US dollars
Nustendi (ezetimibe and bempedoic acid) is prescribed along with a healthy diet to lower cholesterol levels in the blood. High cholesterol (hypercholesterolemia) can lead to atherosclerosis (hardening of the arteries) which occurs when cholesterol, fat, and other substances build up in the walls of arteries. This forms hard structures called plaques which, over time, can block the arteries and cause heart disease, stroke, and other problems.
Ezetimibe inhibits intestinal cholesterol absorption. It differs from other drugs treating hypercholesterolemia because it does not affect the absorption of fat-soluble nutrients such as triglycerides, fat-soluble vitamins, or bile acids. Most of the newer treatments for high cholesterol combine ezetimibe with statins. However, Nustendi combines ezetimibe with bempedoic acid, which has a different mechanism of action. It targets the same biological pathway as statins, but does not have the negative effects that statins can have.


Follow the prescribing doctor’s instructions. The recommended dose of Nustendi is a single tablet taken once each day at the same time, with or without food.

This text is for informational purposes only. Please consult with a doctor or pharmacist before using any medication. 

Nustendi has generally mild side effects, which can include constipation, back pain, and muscle spasms. 

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Nustendi is prescribed along with a low-fat diet to lower blood cholesterol. Cholesterol levels are measured in blood tests. A total cholesterol level below 200 mg/dL is safe, between 200 and 239 mg/dL is borderline high, and 240 mg/dL or higher is considered high.

  • What is bempedoic acid 180 mg and 10 mg of ezetimibe?
    Nustendi is a combination of two different medications that can lower cholesterol levels in the blood. Ezetimibe blocks the absorption of cholesterol in the small intestine. Bempedoic acid inhibits an enzyme called ATP citrate lyase that is required in the liver for synthesis of cholesterol.
  • Why is bempedoic acid better than statins?
    Bempedoic acid targets the same biological pathway that drugs such as atovastatin. However, is not activated until it reaches the liver and this avoids the negative effects that statins can have on the brain, muscles, and other tissues or organs. For this reasone Nustendi doesn't have the same side effects as the equivalent drugs that incorporate statins with ezetimibe.
  • Is it better to take ezetimibe in the morning or at night?
    There is no reason for ezetimibe to be taken at a specific time, however, it should be taken at the same time each day. It can be taken with or without food.
  • How do you know if ezetimibe is working?
    Some people who take ezetimibe do not experience any symptoms of high cholesterol, but this does not mean Nustendi is not working as required. When this medication is taken as prescribed, cholesterol levels should start to drop within two weeks. This will be confirmed by follow-up blood tests.

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