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For visual reference only; actual product may vary
US Name:
Movantik
Alternative Names:
Moventig
Active Ingredients:
Naloxegol
Brand Manufacturer:
Astra Zeneca
Manufacturer Location:
UK
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For visual reference only; actual product may vary
Movantik (naloxegol) is a prescription medication for adults experiencing opioid-induced constipation (OIC). It specifically targets the cause of OIC in the gut, providing effective relief from constipation symptoms without reducing the effectiveness of your opioid pain medicine. Get targeted relief and restore normal bowel function with Movantik.
| Moventig Brand | 25mg 30 Tablets |
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Our price: $193.00 |
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| Moventig Brand | 12.5mg 30 Tablets |
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Our price: $193.00 |
Gut Pack | 30 Pouches 1 Pouch a Day | –+ | Our price: $70.55 |
Movantik is a prescription oral tablet specifically designed to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain. This condition is a common side effect of taking opioid medications for pain management. Movantik helps to relieve constipation symptoms like infrequent bowel movements, straining, and hard stools. It works directly in the gut to counteract the constipating effects of opioids. This medication allows patients to continue their necessary pain treatment while managing this uncomfortable side effect.
Movantik works by selectively blocking opioid receptors in the gastrointestinal tract. Opioid pain medications bind to these mu-opioid receptors not only in the brain to relieve pain but also in the gut, which slows down bowel movements and causes constipation. Movantik, whose active ingredient is naloxegol, is a peripherally acting mu-opioid receptor antagonist (PAMORA). It is designed to limit its entry into the central nervous system. Therefore, it displaces opioids from receptors in the gut to help restore normal bowel function but does not interfere with the pain-relieving effects of the opioid medication on the brain.
Movantik is intended for adult patients who are taking opioid medications for long-lasting pain that is not caused by active cancer. It is for those who are experiencing constipation as a direct result of their opioid use. This medication is a suitable option when traditional over-the-counter laxatives have not provided adequate relief. Your doctor can help determine if Movantik is an appropriate treatment for your specific situation based on your medical history and current medications. It is not meant for patients with constipation from other causes.
Movantik dosage is typically prescribed as one 25 mg tablet taken once daily in the morning. It is very important to take Movantik on an empty stomach. You should take your dose at least one hour before your first meal of the day or two hours after a meal. The tablet should be swallowed whole with water. If you are unable to swallow the tablet, it can be crushed, mixed with four ounces (120 mL) of water, and drunk immediately. Your doctor might recommend a lower starting dose of 12.5 mg if you have certain kidney problems or are taking other specific medications.
Movantik may cause side effects, though most are mild to moderate. The most common side effects include abdominal pain, diarrhea, nausea, headache, and excessive gas. Some people might also experience symptoms of opioid withdrawal, such as sweating, chills, or anxiety. A rare but serious side effect is a tear in the stomach or intestinal wall (gastrointestinal perforation). You should seek immediate medical attention if you experience severe, persistent stomach pain. Always discuss any side effects with your healthcare provider.
IsraelPharm provides a secure and convenient way to purchase Movantik and other essential prescription medications at competitive prices. We are committed to making healthcare more accessible and affordable for our customers in the US. Our licensed pharmacy ensures that all medications are sourced from reputable manufacturers and meet high safety standards. With our user-friendly online platform, you can easily place your order and have it delivered directly to your door, saving you time and money. Experience the reliability and excellent customer service that makes IsraelPharm a trusted choice for your pharmacy needs.
Contact your doctor immediately if you experience severe or persistent stomach pain, as this could be a sign of a rare but serious condition.
Movantik can begin working quite quickly for many individuals. Some people may experience a bowel movement within just a few hours after taking their first dose. For others, it might take a couple of days to see the full benefits and achieve more regular bowel function. Consistency is key, so continue taking Movantik as your doctor prescribed for the best results.
Movantik must be taken on an empty stomach to ensure it is absorbed properly and works effectively. You should take your daily dose at least one hour before you eat your first meal of the day. Alternatively, you can take Movantik two hours after you have finished a meal. Following this instruction is important for the medication's performance.
Movantik is specifically designed to not affect your pain relief. It works as a peripherally acting mu-opioid receptor antagonist, meaning it targets opioid receptors in your gut but does not cross the blood-brain barrier in significant amounts. This allows it to relieve your constipation without reducing the pain-relieving effects of your opioid medication in your brain.
If you miss taking a dose of Movantik, you should just skip the dose you missed. Take your next dose at your regularly scheduled time the following day. It is important that you do not take two doses at once to make up for the missed one, as this can increase your risk of experiencing side effects.
Movantik does not have a major direct interaction with alcohol. However, both alcohol and Movantik can cause side effects like nausea and headaches in some people. Drinking alcohol might worsen these effects. It is always best to consume alcohol in moderation and to discuss your drinking habits with your doctor when starting any new medication.
Your doctor will likely advise you to stop taking other laxative medications before you start treatment with Movantik. This is to prevent excessive bowel movements or diarrhea. If you do not have a bowel movement after three days on Movantik, you should consult your doctor. They may suggest a course of action or re-evaluate your treatment plan.
Movantik should be stored securely at room temperature, between 68°F to 77°F (20°C to 25°C). Keep the tablets in their original container with the lid tightly closed to protect them from moisture and light. As with all prescription drugs, be sure to store Movantik in a safe place that is out of the reach of children and pets.
Movantik may cause symptoms of opioid withdrawal in some patients, although this is not common. Signs to watch for include sweating, chills, diarrhea, yawning, anxiety, irritability, and stomach pain. If you notice any of these symptoms after you start taking Movantik, you should contact your doctor or healthcare provider for professional advice.
Movantik may cause opioid withdrawal in a newborn if taken during pregnancy. You should tell your doctor if you are pregnant or plan to become pregnant before starting this medication. Your doctor will help you weigh the potential benefits against the risks to determine the safest course of action for you and your baby.
Yes, if you have difficulty swallowing pills, the Movantik tablet can be crushed into a powder. The powder should be mixed with 4 ounces (120 mL) of water and then drunk immediately. The same process can be used for administration through a nasogastric (NG) feeding tube. Always consult your pharmacist or doctor for detailed instructions.
The typical starting dose of Movantik is 25 mg taken once daily. However, your doctor may decide to prescribe a lower dose of 12.5 mg. This might be recommended if you have known kidney problems or if you cannot tolerate the side effects of the higher dose. Always follow the specific dosage instructions from your provider.
Movantik is not a treatment for all types of constipation. This medication is specifically indicated for opioid-induced constipation (OIC) in adults who are taking opioid painkillers for chronic non-cancer pain. It is not intended for patients whose constipation is due to other causes. Your doctor will diagnose the cause of your constipation before prescribing this drug.
Movantik use should be approached with caution if you have liver problems. For patients with moderate liver impairment, the dose may be reduced. However, Movantik is not recommended for individuals with severe liver impairment. It is crucial to inform your doctor about the full extent of your liver condition before you start taking this medication.
Movantik can interact with several other medications, which can affect how it works. It should not be taken with strong CYP3A4 inhibitors like ketoconazole or clarithromycin, as this can raise Movantik levels in the blood. You should also avoid moderate CYP3A4 inhibitors and grapefruit juice. Always give your doctor a complete list of your current medications.
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