Lynparza ^*

Lynparza (olaparib) is an advanced cancer drug that belongs to a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. These drugs block a specific enzyme that helps repair damaged DNA in cancer cells. Without those enzymes, the precancerous cells can’t grow and spread. Lynparza is intended for patients with specific genetic mutations and offers targeted therapy for several types of cancer, such as ovarian, breast, pancreatic, and prostate cancers.

Caution

Women should avoid becoming pregnant while taking Lynparza. They should use effective methods of contraception while taking Lynparza and for one month after receiving the last dose. It is necessary to have a pregnancy test before starting Lynparza, at regular times during treatment and one month after receiving the last dose of Lynparza. Talk to the attending doctor immediately if there are any signs of having become pregnant. It is not known whether Lynparza passes into breast milk. Do not breastfeed while taking Lynparza and for one month after receiving the last dose. It is not known whether Lynparza passes into male semen. Men must use a condom when having sex with a female partner, even if she is pregnant, while taking Lynparza and for 3 months after taking the last dose. A female partner must also use a suitable method of contraception. Men must not donate sperm during treatment and for 3 months after taking the last dose.

How to Take Lynparza

Lynparza tablets should be swallowed whole, with or without food, twice daily—once in the morning and once in the evening. Do not chew, crush, dissolve, or split the tablets, as this can affect how the body absorbs the medication.

Dosage

The doctor will specify the number of Lynparza tablets needed. The standard dose is 300 mg (two 150 mg tablets) taken twice daily, for a total of four tablets daily. Always follow instructions when taking Lynparza. If unsure about the dosage or how to take it, consult a doctor or pharmacist. Never exceed the recommended dose. In the case of accidental overdose or if a child swallows the medicine, immediately contact a doctor or go to a hospital emergency room. Bring the package of medicine for reference. If a dose of Lynparza is missed, avoid taking two doses. Instead, take the next regular dose at the usual time and seek advice from a healthcare provider. While undergoing treatment with Lynparza, avoid drinking grapefruit juice, as it can interfere with how the medication works. For more comprehensive information on drug interactions, visit Lynparza website or consult a healthcare provider.

Storage

Keep this medicine securely out of the reach and sight of children and infants to prevent accidental poisoning. Use the medicine before the expiry date indicated on the package, which is the last day of that month. Keep it in its original packaging to protect it from moisture. It doesn’t need special temperature conditions, so storing it at room temperature is fine.

How often will I need blood tests while taking Lynparza?

You will need blood tests before starting treatment, every month during the first year, and at regular intervals decided by your doctor thereafter.

Can I take Lynparza with other medications?

Lynparza may interact with several other medications. Always inform your doctor or pharmacist about any other drugs you are taking, including non-prescription medicines and supplements.

Why should I avoid grapefruit juice while on Lynparza?

Grapefruit juice can affect how Lynparza works in your body, potentially reducing its effectiveness.