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  • US Name:

    Kayexalate Powder

  • Generic Names:

    Kayexalate Powder

  • Active Ingredients:

    Polystyrene Sulphonate

  • Brand Manufacturer:


  • Manufacturer Location:

  • Click here to view Product Insert

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Kayexalate Powder

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Kayexalate powder (polystyrene sulfonate) is used to treat high levels of potassium in the blood.

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Kayexalate Powder Brand powder
1 Bottle (454g)
Our price: $75.00

*Please note all prices are in US dollars
Kayexalate powder is an orally or rectally administered powder indicated for treating high potassium levels in the blood (hyperkalemia).  Kayexalate contains the active ingredient polystyrene sulfonate, which binds potassium ions in exchange for sodium ions. This helps decrease the amount of potassium in the blood, thus lowering the chances of heart rhythm changes due to high potassium levels. This medicine is not absorbed in the body.

If one or more of the following severe side effects are experienced, contact a doctor immediately:

  • Allergic reaction that may appear as a rash, trouble with breathing, or swelling of the face, mouth, tongue, or neck
  • Severe rectal or stomach pain
  • Severe constipation or bloating
  • Severe nausea and vomiting
  • Bloody, black, or tarry stools, vomiting or coughing up blood


Other side effects are listed below and should be reported to a doctor or healthcare provider if experienced:

  • Muscle cramp fits and jitteriness
  • Change in heart rate, exhaustion, muscle weakness, and confusion
  • High blood pressure, swelling of limbs, or problems with heart or kidneys
  • Stomach, abdominal, or gut pain
  • Loss of appetite
  • Nausea 
  • Diarrhea or constipation
  • Coughing or shortness of breath 


Consult a doctor or healthcare provider before using this medication. If any other side effects are experienced, report them to a doctor for further instruction.

Before using this or any other medication, refer to the manufacturer’s product insert that comes with this medication.

Kayexalate powder is indicated for treating high levels of potassium in the blood (hyperkalemia). This condition may be common in patients with renal failure, patients with other medical conditions or patients taking certain medications. 

Kayexalate powder contains a resin that releases sodium ions and binds to potassium ions when it passes through the gastrointestinal tract. This medicine is not absorbed by the body.

  • What is Kayexalate powder used for?
    Kayexalate powder is used to treat hyperkalemia which is a condition of excess potassium in the blood. This medication passes through the body without being absorbed by the body.
  • How much water do I mix with 15 grams of Kayexalate?
    When preparing a dose of 15 grams of Kayexalate it is advised to mix the powder with 20 ml to half a cup of water. Kayexalate powder can also be taken as a paste by mixing it with sweeteners such as jam or honey.
  • How do you mix Kayexalate powder?
    The prescribing doctor should determine the dose of medication, water, and duration of treatment. The prescribed dose of Kayexalate powder should be mixed with the prescribed amount of water or sweetener (honey or jam) and consumed immediately. Do not mix Kayexalate powder with fruit juice, as it may impair the medication's activity.
  • When should Kayexalate be given?
    Kayexalate should be taken three hours before or after any other oral medications. If a patient has gastroparesis, a condition where the stomach does not empty regularly, it is advised to take this medicine six hours after taking any other medications orally. Regardless, this medicine should be given as prescribed by the prescribing doctor.
  • What to avoid while taking Kayexalate?
    While taking Kayexalate, it is advised to avoid taking laxatives, antacids, digoxin, lithium, levothyroxine or thyroxine. These medications may affect the way Kayexalate works. Inform a doctor or healthcare provider if any of the former medications are being taken or have been taken recently as well as any other medicines and supplements.

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