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For visual reference only; actual product may vary

  • US Name:

    Invega Trinza

  • Alternative Names:

    Trivecta

  • Active Ingredients:

    Paliperidone

  • Brand Manufacturer:

    Janssen Cilag

  • Manufacturer Location:

    Belgium

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Invega Trinza *

For visual reference only; actual product may vary

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Invega Trinza is a long-acting injectable antipsychotic treatment. It is given only once every three months. The medication helps manage schizophrenia symptoms and prevent relapse in adult patients who are already stable on a monthly paliperidone injection. It offers a convenient, long-term treatment option.

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Trivecta Brand 175mg
1 Injection
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Trivecta Brand 525mg
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*Please note all prices are in US dollars

What is Invega Trinza?

Invega Trinza is a prescription antipsychotic medication used for the long-term maintenance treatment of schizophrenia. It is an injectable suspension containing the active ingredient paliperidone palmitate. This medication is unique because it is administered only once every three months. It is intended for adult patients who have already been adequately treated with a one-month paliperidone injection for at least four months. Invega Trinza helps to manage symptoms and prevent the recurrence of psychotic episodes. This extended-release formula provides a consistent level of medication in the bloodstream. This helps ensure therapeutic effects are maintained over the long term.

How does Invega Trinza work?

Invega Trinza works by rebalancing certain natural chemicals in the brain called neurotransmitters. Specifically, its active ingredient, paliperidone, primarily affects dopamine and serotonin pathways. It is thought to block the activity of D2 dopamine receptors and 5-HT2A serotonin receptors. By modulating the function of these neurotransmitters, Invega Trinza helps to control the symptoms of schizophrenia. These symptoms can include hallucinations, delusions, and disorganized thinking. The long-acting formulation ensures that these effects are sustained for three months after a single injection. It provides continuous symptom management without the need for daily medication.

Who is Invega Trinza for?

Invega Trinza is for adults diagnosed with schizophrenia who are seeking a long-term maintenance therapy. The ideal candidate is someone who is already clinically stable. This means their symptoms are well-controlled. They must have been successfully treated with the one-month paliperidone palmitate injection (Invega Sustenna) for at least four months. This treatment is best for patients who prefer an infrequent dosing schedule. A three-month injection can improve convenience and adherence to treatment. It is not for treating acute episodes of schizophrenia or for patients just starting treatment.

Dosage and administration

Invega Trinza is administered by a healthcare professional once every three months. It is given as a single intramuscular injection. The injection site is typically the deltoid muscle in the arm or the gluteal muscle in the buttock. The dosage of Invega Trinza is determined based on the patient’s previous dose of the one-month paliperidone injection. There is no need for a loading dose or oral supplementation when transitioning. It’s critical that patients adhere to their quarterly injection schedule. This ensures the medication level in the body remains stable. Do not attempt to self-administer this medication.

Side effects

Invega Trinza can cause side effects, though not everyone will experience them. The most common side effects include:

  • Reactions at the injection site (such as pain, redness, or swelling)
  • Weight gain
  • Headache
  • Upper respiratory tract infections
  • Drowsiness or sleepiness
  • Akathisia (a feeling of inner restlessness)

More serious side effects can occur. These may include neuroleptic malignant syndrome (a rare but serious reaction), tardive dyskinesia (uncontrolled body movements), and changes in heart rhythm. It may also cause metabolic changes like high blood sugar. You should discuss any concerning side effects with your doctor immediately.

Why buy from IsraelPharm?

Choosing IsraelPharm for your Invega Trinza prescription offers significant advantages. We provide a reliable and convenient source for your long-term medication needs. Our prices are competitive, helping you save money on your treatment. We source our medications from licensed suppliers. This ensures you receive authentic and safe products. Our customer service team is knowledgeable and ready to assist with your order. With discreet and direct shipping, managing your schizophrenia treatment is simpler and more affordable. Trust IsraelPharm for professional service and peace of mind.

Like all antipsychotics, Invega Trinza may cause side effects. Many are mild and manageable.

Common Side Effects:

  • Injection site reactions (pain, swelling, or redness)
  • Weight gain
  • Drowsiness or sedation
  • Headache
  • Akathisia (feelings of restlessness)
  • Upper respiratory tract infections
  • Increased heart rate

Less Common but Serious Side Effects:

  • Tardive dyskinesia (involuntary, repetitive body movements)
  • Neuroleptic Malignant Syndrome (fever, muscle rigidity, altered mental status)
  • Metabolic changes (high blood sugar, high cholesterol)
  • Orthostatic hypotension (dizziness upon standing)
  • Seizures

If you experience any severe or persistent side effects, contact your healthcare provider immediately.

  • Maintenance treatment of schizophrenia: For adult patients who are clinically stable after treatment with a 1-month paliperidone palmitate injectable product.

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