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For visual reference only; actual product may vary

  • US Name:

    Dificid

  • Alternative Names:

    Dificlir

  • Active Ingredients:

    Fidaxomicin

  • Brand Manufacturer:

    Tillots

  • Manufacturer Location:

    Switzerland

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Dificid *

For visual reference only; actual product may vary

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Dificid/Dificlir is specifically indicated for the treatment of complications that have arisen as a result of infection by the C. difficile bacteria in adults

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Dificlir Brand 200mg
20 Tablets
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Our price:
$2,200.00

*Please note all prices are in US dollars
Dificid/Dificlir (generic name: fidaxomicin) is an antibiotic medication specifically indicated for the treatment of C. difficile-associated diarrhea (CDAD). This serious bacterial infection can cause severe diarrhea, colitis, and other gastrointestinal issues, often after an antibiotic course that disrupts the balance of good bacteria in the gut. Fidaxomicin works by inhibiting the bacterial enzyme RNA polymerase, effectively stopping the growth and replication of the C. difficile bacteria. Fidaxomicin is currently only approved for use in adults. Fidaxomicin is primarily effective in treating CDI because of its narrow spectrum of activity. It targets the C. difficile bacteria without disrupting other beneficial bacteria in the gastrointestinal tract. It is not indicated for other types of bacterial infections. Unlike many other antibiotics, Dificid is minimally absorbed into the bloodstream and primarily works in the gut, where C. difficile causes infection. This targeted action helps preserve the normal gut flora, reducing the likelihood of recurring infections. For more information, visit the manufacturer’s website.

Dosage

It is essential to adhere to the prescribing doctor’s specification. Dificid is usually prescribed to be taken twice daily for ten days. The tablet can be taken with or without food, and it is essential to complete the entire course of treatment, even if symptoms improve before finishing the medication.

Storage

Dificid should be stored at room temperature (68-77°F/20-25°C), away from moisture and direct sunlight. Do not store it in the bathroom; keep it out of reach of children and pets. For more guidance, consult our blog on safe medicine management.

Common Questions About Dificid

Is Clostridium difficile serious?
C. difficile is a bacterium that can cause an infection of the longer part of the large intestine. Symptoms can range from diarrhea to life-threatening damage.
Can Clostridium difficile cause permanent damage?
The toxins produced by C. difficile can irritate the lower part of the gut, resulting in colitis, in which the colon swells and becomes inflamed. If this goes untreated, the walls of the gut can rupture. In such a case, the damaged stretch has to be removed by surgery, which can leave scars and longer-term problems.
How do I know if my Clostridium difficile is gone?
A stool test to check for the bacteria or the toxins that C. diff causes is the only certain way. Even if the symptoms of colitis or diarrhea appear to have stopped, it is essential to consult with a doctor and to keep taking Dificid until the course is finished.
How does Dificid differ from other antibiotics used to treat Clostridioides difficile infection?
Dificid is a narrow-spectrum antibiotic that specifically targets C. difficile bacteria, while other antibiotics, such as Vancocin and Flagyl, may also kill a broader range of bacteria. This targeted approach helps to preserve the healthy bacteria in the gut, reducing the risk of recurrence of the infection.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Read the information leaflet that comes with the medication.

Very rarely, people taking fidaxomicin can have a sudden allergic reaction (anaphylaxis), with symptoms like swelling of the face, tongue, or throat, making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

Most people who use Dificid do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include

  • Nausea
  • Vomiting
  • Stomach pain
  • Constipation
  • Decreased appetite
  • Dizziness
  • Headache
  • Adry mouth or altered taste (dysgeusia)
  • Flatulence (feeling bloated with wind)
  • Rash
  • Itching (pruritus).

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Dificid is FDA-approved for the treatment of Clostridioides difficile infection in adults. The condition is characterized by frequent, watery diarrhea, abdominal cramping, and fever. In severe cases, CDI can lead to dehydration, hospitalization, and even death.

  • Can infection by C. difficile have serious consequences?
    There are serious possible outcomes from infection by C. difficile. Nearly nine percent of all people over the age of 65 who develop this after treatment for another bacterial infection die within one month unless there is proper intervention.
  • How to diagnose CDI?
    There are polymerase chain reaction (PCR) assays that the FDA has approved as same-day tests that are highly sensitive and specific for the presence of C. diff organism, even in asymptomatic individuals and those who do not have an infection.
  • What is the incidence of infection by C. difficile?bacteria?
    C. difficile is a bacterium that can cause diarrhea and more serious intestinal conditions such as colitis. It causes close to half a million illnesses each year in the US.
  • Can Dificid be taken if the infection has recurred after other treatments?
    es, Dificid is often prescribed for recurrent Clostridioides difficile infections because its targeted mechanism of action may reduce the risk of future recurrence. A healthcare provider will determine if it is appropriate based on the patient’s medical history and prior treatments.
  • Can Dificid be taken alongside other medications?
    As with all medications, it is important to inform the prescribing healthcare provider of all other drugs being taken, including over-the-counter medications and supplements. While Dificid has a low potential for drug interactions due to its minimal absorption into the bloodstream, it is essential to check with a healthcare provider to ensure there are no risks.
  • What should I do if I miss a dose of Dificid?
    If a dose of Dificid is missed, take it as soon as it is remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up. It is important to complete the full course of antibiotics, even if symptoms improve.
  • Is it safe to drink alcohol while taking Dificid?
    There are no direct contraindications between alcohol and Dificid. However, alcohol consumption can cause dehydration and gastrointestinal irritation, which may worsen symptoms of C. difficile infection. It is best to avoid alcohol while recovering from the infection to support overall healing.

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