Spend $99, get free U.S. shipping*

Tariff now required on U.S. shipments. Learn more »

Tel: 1-866-456-3768 Fax: 1-866-544-8993

For visual reference only; actual product may vary

  • US Name:

    Diane

  • Alternative Names:

    Diane, Estelle

  • Active Ingredients:

    Cyproterone and Ethinylestradiol

  • Brand Manufacturer:

    Bayer

  • Manufacturer Location:

    Germany

  • Click here to view Product Insert

  • Click here to view Product Insert

Diane *

For visual reference only; actual product may vary

Prescription Required
All third-party products, company names, and logos are trademarks™ or registered® trademarks are and remain the property of their respective holders. Their use does not imply any affiliation with or endorsement by them. All references on this site to third-party trademarks are intended to constitute nominative fair use under applicable trademark laws.

Diane is a combination oral medication containing cyproterone and ethinylestradiol. It is prescribed to treat hormone-driven conditions in women, such as severe acne and hirsutism (excessive hair growth), while also functioning as an effective oral contraceptive. It works by regulating hormones to address skin issues and prevent pregnancy.

Place your order

Diane Brand 2mg / 0.035mg
21 Tablets
-
+
Our price:
$24.00

*Please note all prices are in US dollars

What is Diane?

Diane is an oral prescription medication that contains two active ingredients: cyproterone acetate, an anti-androgen, and ethinylestradiol, a synthetic estrogen. It is specifically designed for women to treat androgen-dependent conditions, which are health issues driven by an excess of male hormones. These conditions most notably include severe acne that has not responded to other treatments and hirsutism (excessive hair growth in a male-like pattern). Due to its hormonal composition, Diane also functions as an effective oral contraceptive, preventing pregnancy while it treats the underlying skin or hair condition.

How does Diane work?

Diane works through a dual-action mechanism thanks to its two active ingredients. The cyproterone acetate component directly counteracts the effects of androgens (male hormones like testosterone) in the body. It does this by blocking the receptors that androgens bind to, which reduces sebum (skin oil) production, a key factor in acne. It also slows down unwanted hair growth. The ethinylestradiol component, a type of estrogen, enhances this effect and, crucially, regulates the menstrual cycle. Together, they prevent the ovaries from releasing an egg (ovulation), thicken the cervical mucus to block sperm, and alter the uterine lining to prevent a fertilized egg from implanting, making it a reliable contraceptive.

Who is Diane for?

Diane is primarily intended for women who are dealing with significant, androgen-dependent health issues and who also desire oral contraception. This includes women with severe, persistent acne that has proven resistant to topical treatments or oral antibiotics. It is also prescribed for those with moderate to severe hirsutism (unwanted facial or body hair). It is important to note that Diane is not typically a first-line contraceptive. It is specifically chosen when a patient has these hormonal symptoms and requires contraception, allowing both issues to be managed with a single medication under a doctor’s supervision.

Dosage and administration

Diane is typically administered in a 28-day cycle, taken as one tablet orally each day. The pack contains 21 active pills, which are taken consecutively for three weeks, followed by a 7-day period where no pill is taken (or a placebo pill is taken, depending on the packaging). This 7-day break allows for a withdrawal bleed, similar to a menstrual period. For maximum contraceptive effectiveness, the pill should be taken at the same time every day. Starting regimens and what to do in case of a missed dose should be followed precisely as instructed by your healthcare provider and as detailed in the patient information leaflet.

Side effects

Like all hormonal medications, Diane may cause side effects in some users, though not everyone will experience them. Common side effects can include nausea, headaches, breast tenderness, mood swings, and changes in body weight. Some women may also experience changes in their libido or see spotting between periods, especially in the first few months of use. More serious, but less common, side effects include an increased risk of blood clots (venous thromboembolism), which can be dangerous. It is critical to discuss your full medical history, including any risk factors like smoking or a history of migraines, with your doctor before starting Diane.

Why buy from IsraelPharm?

Buying from IsraelPharm ensures you receive authentic, brand-name medication like Diane in a safe, convenient, and affordable manner. We source our products from reputable manufacturers and licensed distributors, so you can be confident you are getting the same high-quality medication you would at a local pharmacy. Our streamlined online platform and dedicated customer service team make the ordering process simple, while our competitive pricing structure helps you manage your healthcare costs effectively without compromising on quality or safety. We are committed to providing reliable access to the medications you need.

Patients taking Diane may experience side effects. It is important to consult a doctor about potential risks.

Common Side Effects

  • Nausea or vomiting
  • Headaches or migraines
  • Breast tenderness, pain, or enlargement
  • Changes in body weight or fluid retention
  • Mood changes, including depression
  • Spotting or breakthrough bleeding

Serious Side Effects (Less Common)

  • Blood Clots (Thrombosis): Increased risk of developing dangerous clots in the legs, lungs, or brain.
  • Cardiovascular Issues: Potential for increased blood pressure.
  • Liver Problems: In rare cases, liver function can be affected.
  • Severe Depression: Worsening of mood that requires medical attention.

Diane (Cyproterone/Ethinylestradiol) is primarily indicated for the treatment of androgen-dependent conditions in women. These include:

  • Severe Acne: Particularly for cases that have not responded to treatments like oral antibiotics or topical therapies.
  • Hirsutism: For the management of moderate to severe cases of excessive or unwanted hair growth on the face and body.

As a secondary function, Diane also provides effective oral contraception for women being treated for the above conditions.

Getting started with IsraelPharm

Required

Send Your Prescription

Secure Payment

No Hidden Fees

Fast Shipping

Generally 7-10 Business Days

Fast delivery
Secure payment
Genuine brands
Pharmacist oversight
Proudly Israeli

Ordering is
simple and safe.

IsraelPharm has been delivering lost cost prescriptions from Israel for over 15 years worldwide. Daily flights allow us to get your medications dispatched fast! Delivery to the USA is under 10 days and you can track and trace every order.

Read more from our blog

estrogen patch shortage solved

Estrogen Patch Shortage? How to Get Yours

The stimulus for this article came from a cry for help from a person who had never before considered sourcing her medications from anything other than traditional “brick-and-mortar” local pharmacies, but was driven to desperation

Read More »

Login

Fast Delivery
Ships from Israel
Secure Payment
Genuine Brands
Pharmacist Oversight
Proudly Israeli
Free Shipping on orders over $99*

Having issues?

Daily from 9am-8pm EST.
IsraelPharm
Hataasia 16
Bet Shemesh Israel, 9906105

Sign up for $10 off your first order!

Enjoy exclusive deals we only share via email