Complera ^*

Complera (generic names: emtricitabine, rilpivirine, and tenofovir DF) is a complete regimen for treating HIV infection. Emtricitabine (brand name Edurant®) and tenofovir DF (brand name VIREAD®) are human immunodeficiency virus nucleotide/nucleoside analog reverse transcriptase inhibitors (NRTIs), and rilpivirine (brand name Edurant®) is an HIV non-nucleoside analog reverse transcriptase inhibitor (NNRTI). The three components are combined into a single pill.

NRTIs work by blocking an enzyme called reverse transcriptase, which HIV needs to make copies of itself. By preventing this enzyme from working, NRTIs stop the virus from replicating. NNRTIs block the HIV-1 reverse transcriptase enzyme, preventing the virus from replicating. NNRTIs are typically combined with other antiretroviral drugs, such as NRTIs and integrase inhibitors, to suppress the virus effectively.

Complera does not cure HIV infection or AIDS. and does not reduce the risk of passing HIV to others. You must continue to see your doctor regularly while taking Complera.

Dosage

Take Complera every day exactly as prescribed on the label. Set up a dosing schedule and follow it carefully. A dose must be taken with food, which will help absorption. A protein drink is not a substitute for food. Talk to a healthcare provider, nurse practitioner, or nutritionist for guidance about the minimum food needed for Complera to work properly. If you are taking an antacid to treat heartburn or GERD, it should be taken at least two hours before or four hours after taking a dose of Complera.

The usual dose of Complera is one tablet with food once a day, with plenty of water. If a scheduled dose was missed but can be taken within 12 hours of the scheduled time, take it immediately with food, and then continue with the regular schedule. If more than 12 hours have elapsed, then go back to the regular schedule. Do not double-dose to make up for a missed dose. In case of accidental overdose, contact a doctor, emergency health center, or poison control center even if no symptoms are felt.

Storage

Complera should be stored at 15-30°C (59-86°F). Store Complera in its original container and keep the container tightly closed. If the seal is broken or tampered with, do not use Complera and return the package to the pharmacy for replacement.

Questions people ask about Complera

What is the difference between NNRTIs and NRTIs?

NNRTIs directly bind to and inhibit reverse transcriptase. They compete with naturally occurring nucleosides and bind to the viral RNA chain. Medications with NRTIs and NNRTIs both slow down HIV replication.

What is antiretroviral therapy for HIV?

Antiretroviral therapy (ART), also known as highly active antiretroviral therapy (HAART), is a combination of medications used to treat HIV infection. ART aims to suppress HIV, preventing it from multiplying and damaging the immune system. It’s a lifelong treatment that significantly improves the quality of life and life expectancy of people living with HIV.