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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Complera is a prescription medication that combines three active ingredients into a single, once-daily pill for the treatment of HIV-1 infection. It simplifies HIV treatment by reducing the number of pills you need to take, making it easier to stick to your regimen and manage the virus effectively.
| Complera Brand | 200mg/25mg/300mg 30 Tablets |
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Our price: $1,800.00 |
Complera is a complete prescription regimen used for the treatment of HIV-1 infection in adults and children weighing at least 35 kg. It is a single-tablet combination of three active drugs: emtricitabine, rilpivirine, and tenofovir disoproxil fumarate (TDF). This medication is designed for patients who are either new to antiretroviral therapy or are virologically suppressed (HIV-1 RNA less than 50 copies/mL) on a stable regimen. By combining three drugs into one pill, Complera simplifies the treatment process, making it more convenient for patients to manage their condition effectively.
Complera works by combining the mechanisms of its three active ingredients to stop the HIV virus from replicating in the body. Emtricitabine and tenofovir DF are Nucleoside Reverse Transcriptase Inhibitors (NRTIs), while rilpivirine is a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Both types of drugs target a crucial enzyme called reverse transcriptase, which HIV needs to make copies of its genetic material. The NRTIs act as faulty building blocks, while the NNRTI directly binds to and disables the enzyme. By inhibiting this enzyme in two different ways, Complera effectively lowers the amount of HIV in the blood (viral load), allowing the immune system to recover.
Complera is intended for use by adults and adolescents (weighing at least 77 lbs or 35 kg) for treating HIV-1 infection. It is typically prescribed for individuals who are starting antiretroviral therapy for the first time and have a viral load of 100,000 copies/mL or less. It can also be used to replace a current antiretroviral regimen in patients who have been virologically suppressed for at least six months, have no history of treatment failure, and are not resistant to any of the three components in Complera. A healthcare provider will determine if this single-tablet regimen is the right choice based on a patient’s specific medical history and viral characteristics.
The standard dosage for Complera is one tablet taken orally, once per day, and it must be taken with a meal. Taking the medication with food, particularly a meal that contains some fat, is critical as it helps the body absorb the rilpivirine component properly. A protein drink alone is not a substitute for a food-based meal. It is important to take Complera at the same time each day to maintain consistent levels of the drug in your system. If you miss a dose, take it with food as soon as you remember. However, if it’s almost time for your next dose (within 12 hours), skip the missed dose and resume your regular schedule. Do not take two doses at once to make up for a missed one.
While Complera helps manage HIV, it can cause side effects, though not everyone experiences them. The most common side effects include trouble sleeping, headache, dizziness, nausea, and rash. More serious side effects can occur, such as a buildup of lactic acid in the blood (lactic acidosis), severe liver problems, new or worsening kidney issues, bone density loss, and mental health problems like depression or mood changes. It is crucial to contact your healthcare provider immediately if you experience unusual muscle pain, stomach pain with nausea, severe tiredness, or yellowing of the skin or eyes. An allergic reaction is also possible and requires emergency medical attention.
Choosing IsraelPharm for your medication needs provides a blend of affordability, reliability, and convenience. We source our medications, including brand-name options like Complera, from legitimate, regulated suppliers, ensuring you receive the same authentic products you would from a local pharmacy. Because of differences in international drug pricing, we are able to offer significant savings. Our streamlined online ordering process is overseen by experienced pharmacists, providing a secure and professional service that delivers your vital HIV treatment directly to your door, saving you time and money without compromising on quality or safety.
Like all medications, Complera can cause side effects, although not everybody gets them. Your doctor has prescribed this because they believe the benefit is greater than the risk of side effects.
Common side effects may include:
Seek immediate medical attention for serious side effects, such as:
This is not a complete list. Consult your doctor or pharmacist for more information.
Complera is a prescription medication indicated for the treatment of Human Immunodeficiency Virus-1 (HIV-1) infection in specific patients. HIV is a virus that attacks the body’s immune system. If left untreated, it can lead to Acquired Immunodeficiency Syndrome (AIDS).
Early signs of HIV infection can resemble the flu and may include:
Complera helps to control the virus but is not a cure for HIV.
If you miss a dose of Complera, take it with a meal as soon as you remember. If it has been more than 12 hours since your scheduled dose, just skip the missed dose and take the next one at your regular time. Do not take two doses at once to make up for the missed one. Maintaining a consistent schedule is very important for the medication to be effective against the HIV virus.
Yes, it is essential to take Complera with a meal. This is not optional. The food helps your body properly absorb the rilpivirine component of the medication, ensuring it works effectively to control the HIV virus. A protein shake or a light snack is not sufficient; it should be a full meal. Your doctor or a nutritionist can provide guidance on the type and size of the meal required.
No, Complera does not cure HIV or AIDS. It is an antiretroviral therapy that works by suppressing the HIV virus, which stops it from multiplying and reduces the amount of the virus in your body (viral load). This helps your immune system stay healthy but does not eliminate the virus completely. It's a lifelong treatment to manage the condition, not a cure.
The most frequently reported side effects for Complera include difficulty sleeping (insomnia) and abnormal dreams, headache, dizziness, nausea, and rash. Many people taking Complera do not experience major side effects, and some effects may lessen over time as your body adjusts. If any side effects persist or become bothersome, it is important to talk with your healthcare provider.
You need to be careful. Antacids that contain aluminum, magnesium, or calcium should be taken at least two hours before or four hours after you take Complera. Acid reducers like famotidine (Pepcid) should be taken 12 hours before or 4 hours after Complera. However, proton pump inhibitors (PPIs) like omeprazole (Prilosec) or esomeprazole (Nexium) must not be taken at all with Complera as they can severely lower its effectiveness.
Complera contains three active drugs that attack the HIV virus in two different ways. Two of the drugs (emtricitabine and tenofovir DF) are NRTIs, which act as faulty building blocks to stop the virus from copying its own genetic material. The third drug (rilpivirine) is an NNRTI, which directly binds to and blocks the enzyme (reverse transcriptase) that the virus needs to replicate. This combined action effectively suppresses the virus.
You should never stop taking Complera or any antiretroviral medication without first consulting your doctor. Suddenly stopping can cause the amount of HIV in your blood to increase rapidly. This can weaken your immune system and make the virus resistant to Complera or other HIV medications in the future. If you also have Hepatitis B, stopping Complera can cause a severe flare-up of the infection.
Yes, Complera contains tenofovir disoproxil fumarate (TDF), which can have effects on the kidneys and bones. It may cause a decrease in kidney function or lead to a loss of bone mineral density over time. Your doctor will monitor your kidney function and bone health through regular blood tests and may recommend specific supplements like calcium and vitamin D. Report any new bone pain to your doctor.
While moderate alcohol consumption is generally not prohibited, it's wise to discuss it with your doctor. Alcohol can put extra strain on the liver, and serious liver problems are a potential side effect of Complera. Additionally, alcohol can impair judgment, which might make you forget to take your medication on time. For your overall health and to ensure the medication works best, limiting alcohol is a good idea.
You should inform your doctor immediately if you are pregnant or planning to become pregnant. Complera and its components have been studied in pregnancy, but the decision to use it requires careful consideration. Your healthcare provider will weigh the potential benefits to you against any potential risks to the baby and may discuss alternative treatment options. There is a registry to monitor outcomes for pregnant women taking antiretroviral medications.
Yes, mood changes, including depression and anxiety, have been reported as a side effect of Complera, primarily linked to the rilpivirine component. It is very important to tell your healthcare provider immediately if you experience feelings of sadness, major mood changes, or have thoughts of harming yourself. Your doctor can help determine the cause and recommend the best course of action for your mental well-being.
Complera should be stored at room temperature, between 68°F to 77°F (20°C to 25°C). Keep it in its original container with the cap tightly sealed to protect it from moisture. Store it in a dry place away from heat and direct sunlight, and make sure to keep it out of the reach of children and pets. Do not store it in a bathroom medicine cabinet where humidity is high.
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