Myrbetriq (generic name: mirabegron) is the most frequently prescribed slow-release generic tablet used to treat the condition known as overactive bladder (OAB) in adults. The medication is also used to treat neurogenic detrusor overactivity.
People suffering from bladder control may experience symptoms of urgency, frequency and leakage in passing urine.
Overactive bladder is a condition coming primarily from how the bladder stores urine. Neurogenic detrusor overactivity is caused by brain, spinal cord, or nerve problems that affect the bladder’s storage control.
As well as its effects in bladder control, some recent studies of the effects of mirabegron have found that it can increase basal heart rate, metabolic rate and blood pressure which are signs of cardiovascular stimulation.
What are the Symptoms of Overactive Bladder (OAB)?
Symptoms of OAB and neurogenic detrusor overactivity may include frequent urination, involuntary loss of urine (incontinence), or sudden strong urges to urinate that are hard to control. OAB can affect your lifestyle by making your movements dependent on the availability of toilets wherever you go, restricting travel and socialization, and disturbing your rest at night.
How Does Myrbetriq Work?
Myrbetriq works on a unique pathway by promoting the excretion of an alpha1-adrenoceptor blockade. This distinguishes it from other generic treatments for OAD. It relaxes the detrusor bladder muscle. In turn, this helps the bladder fill more completely and increases the volume of urine being stored.
It thereby lessens the symptoms of overactive bladder and neurogenic detrusor overactivity.
What are the Side Effects of Myrbetriq?
Some of the mild side effects of Myrbetriq are:
- Rapid heartbeat
- Runny/stuffy nose
If these are persistent, lasting more than a few days or if they get steadily worse, you should discuss this with your prescribing doctor or dispensing pharmacist.
There are rare but more severe side effects, which you must report to your doctor immediately. These are:
- allergic reactions
- raised blood pressure
- pain or swelling of the nose or throat (nasopharyngitis)
- urinary tract infection.
Myrbetriq may increase your chances of not being able to empty your bladder. If you have a weak urine stream or persistent trouble emptying your bladder, you must tell your doctor right away.
Although it is rare, if you experience an allergic reaction with swelling around your face, lips, throat or tongue, you must stop using Myrbetriq immediately. Go to the nearest hospital emergency room right away, informing them that you have been taking this drug.
How do doctors diagnose OAB?
The main indications of OAB are increased need to urinate frequently along with urgency and incontinence (leakage). The usual benchmark is if you need to urinate more than seven times each day, especially frequently at night, or if leakage occurs.
What are the precautions I should take?
Your doctor will have taken all of these necessary factors into account when prescribing Myrbetriq and have decided that the benefits outweigh the risks or adverse effects. However, you can still be aware of the main precautions to avoid accidentally causing some change.
- Tell your doctor or pharmacist about any other bladder problems (such as blockage), high blood pressure, kidney or liver problems.
- Limit your intake of alcohol and talk to your doctor if you are using cannabis
- Tell the surgeon or dentist before having surgery that you are being treated with Myrbetriq.
- During pregnancy, your prescribing doctor will only have decided on this treatment because it is needed. If you fall pregnant when already on Myrbetriq, discuss this with both the prescribing physicians and your obstetrician.
Myrbetriq is sold on IsraelPharm as Betmiga in 25 mg and 50 mg.