What is Actigall?
Actigall is a prescription medication whose active ingredient, ursodeoxycholic acid, is a naturally occurring bile acid. It is primarily used to treat specific gallbladder and liver conditions. For the gallbladder, Actigall helps dissolve gallstones made of cholesterol, offering a non-surgical option for patients. For the liver, it is used to manage chronic diseases like primary biliary cirrhosis (PBC) by improving the flow of bile and protecting liver cells from damage.
How does Actigall work?
Actigall works by reducing the amount of cholesterol produced by the liver and decreasing its absorption in the intestines. This change in the composition of bile makes it less likely to form stones and helps to gradually dissolve existing cholesterol-based gallstones. In chronic liver diseases, ursodeoxycholic acid protects liver cells from being damaged by toxic bile acids, improves liver function, and reduces inflammation by facilitating better bile flow out of the liver.
Who is Actigall for?
Actigall is primarily for patients with small, non-calcified (radiolucent) cholesterol gallstones who have a functioning gallbladder but are not good candidates for gallbladder surgery (cholecystectomy). It is also prescribed for individuals diagnosed with chronic cholestatic liver diseases. This includes conditions such as Primary Biliary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), and liver complications associated with cystic fibrosis. Doctors may also prescribe it to prevent gallstone formation in overweight patients undergoing rapid weight loss.
Dosage and administration
The correct dosage of Actigall is determined by a healthcare professional based on the specific condition being treated, the patient’s body weight, and their overall health profile. Actigall is an oral medication that comes in capsule form and is typically taken two to three times a day, often with meals to enhance absorption and reduce potential stomach upset. For treatment to be effective, the medication must be taken consistently as prescribed, often over a period of months or even years, especially for dissolving gallstones.
Side effects
Like all medications, Actigall may cause side effects, though not everyone experiences them and they are often manageable. The most frequently reported side effect is diarrhea or pasty stools. Less common side effects can include nausea, vomiting, or upper abdominal pain. In rare cases, patients might experience skin reactions like itching or hives, or see calcification of their gallstones, which could make the medication less effective. It is important to discuss any persistent or bothersome side effects with your doctor.
Why buy from IsraelPharm?
Choosing IsraelPharm for your Actigall prescription ensures you receive genuine, high-quality medication at a competitive price. We source our products from reputable manufacturers and licensed distributors, giving you peace of mind about safety and efficacy. Our convenient online platform allows you to securely order your medication from the comfort of your home and have it delivered directly to you in the US, combining affordability with world-class service and a commitment to your health and well-being.
The most common side effects associated with Actigall may include:
Other, less common side effects that have been reported are:
- Nausea and vomiting
- Upper abdominal pain
- Calcification of gallstones
- Hives (urticaria)
- Itching of the skin (pruritus)
You should consult your doctor or another healthcare provider if you experience any persistent or concerning side effects while taking this medication.
Actigall (Ursodeoxycholic Acid) is indicated for the treatment of several conditions, including:
- Dissolving or reducing the size of radiolucent cholesterol gallstones in patients with a functioning gallbladder.
- Treatment of various chronic liver diseases, such as:
- Primary Biliary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Cystic fibrosis-related liver disease
- Biliary atresia
- Chronic and alcoholic hepatitis