Intuniv XR (
generic name: guanfacine)Â is a
non-stimulant extended-release tablet used to treatÂ
Attention-deficit/Hyperactivity Disorder (
ADHD)Â in children and adolescents aged 6 to 17 years. It belongs to the class of medicines calledÂ
alpha-2A adrenergic agonists. Guanfacine works by strengthening regulation of attention and impulse control through its action on the prefrontal cortex. It can be taken alone or alongside stimulant medicines, providing symptom relief without the abuse potential of stimulants. Treatment is once daily, designed for steady coverage throughout the day. Learn more fromÂ
MedlinePlus.
Usual dosage
It is important to follow the dosage instructions printed on the label of the box.
The usual starting dose isÂ
1 mg once daily, taken in the morning or evening. The dose may be increased byÂ
1 mg per week depending on response, typically reachingÂ
3–4 mg daily. The maximum dose isÂ
4 mg/day in children 6–12 years andÂ
7 mg/day in adolescents 13–17 years. Dosing may also be weight-based (0.05–0.12 mg/kg/day).
Tablets should be swallowed whole. Do not crush or chew. If a dose is missed, skip it and continue with the next scheduled dose.
Do not double dose to make up for a missed dose.
Caution:Â do not discontinue abruptly, as this may cause rebound high blood pressure; taper gradually under medical advice.
Standard storage
Store Intuniv XR tablets atÂ
20-25 °C (68-77 °F). Protect from moisture and light. Store in the original container with the cap closed.
Keep out of reach of children. Do not use beyond the expiry date, which refers to the last day of the month printed on the package.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.
The information leaflet that comes with the medication includes full information about the possible side effects. Be sure to read and understand these, and if there are any questions, discuss these with a healthcare provider or pharmacist before starting treatment.
Caution
If a sudden allergic reaction (anaphylaxis) occurs shortly after taking Intuniv XR, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.
Pregnant women should not be using Intuniv XR unless this has been discussed with a healthcare provider, as it might harm the unborn baby or pose a risk of miscarriage. For this reason, women planning to become pregnant should use appropriate birth control measures during treatment and when tapering off. Intuniv XR may pass into breast milk, and mothers should consult with a doctor if already feeding or planning to feed an infant.
Most people who use Intuniv XR do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.
Some of the side effects that have been reported include:
- Drowsiness or sleepiness
- Dizziness or lightheadedness
- Dry mouth
- Constipation
- Headache
- Fatigue
Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.
Intuniv XR is approved to treat ADHD in children and adolescents aged 6 to 17 years, either alone or as add-on therapy to stimulant medicines. It helps reduce hyperactivity, inattention, and impulsivity, improving focus and daily functioning.
Guanfacine may also be used off-label for related conditions such as tics, aggression, anxiety, and sleep disturbances, but these uses require specialist guidance.