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Zylan is a prescribed medication to be taken along with a comprehensive smoking cessation support program to stop smoking.

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Zyban Brand 150mg
60 Capsules
Our price: $98.00

*Please note all prices are in US dollars
Zyban (generic: bupropion hydrochloride 150 mg) can be prescribed along with a comprehensive smoking cessation support program as an aid to stop smoking. Although the precise mechanism of how bupropion works has not yet been discovered, it is believed to reduce craving for nicotine by blocking some of the chemicals in the brain that react with nicotine to generate dopamine, the “pleasure” neurotransmitter.


Take Zyban exactly as prescribed. Usually, treatment should begin two weeks before a preset date (the Target Stop Smoking Date) and start with one tablet each day, increasing to the full prescribed dose at the end of the first week while still smoking.   Take Zyban with or without food at approximately the same time each day. Swallow the tablets whole. Do not chew, crush or split them. This can cause the medicine to be released too quickly and can produce unwanted side effects.   If a scheduled dose has been missed, take the next dose at the usual time. Do not double-dose to make up for a forgotten dose.

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Please read the Product Insert that comes with the medication.

Some mild side effects may be felt. Ask your doctor or pharmacist for advice if you feel depressed, anxious, dizzy, or have difficulty concentrating.

Other side effects include:

  • Tremors
  • Headaches
  • Nausea or vomiting
  • Abdominal pain
  • Constipation
  • Changes in the taste of food
  • Dry mouth
  • Fever
  • Sweating
  • Allergic skin rash
  • Itching.

Not all side effects are listed here. Consult a healthcare provider if you experience these or other unexpected effects.

Zylan helps people who are trying to stop smoking. It can be prescribed alongside a comprehensive smoking cessation support program.

Zylan does not contain nicotine or nicotine substitutes. Its mechanism of action is to block the craving for nicotine in the brain by inhibiting the reuptake of the neurotransmitters dopamine and norepinephrine, which produce the sense of pleasure that comes from smoking.

  • How much Zyban (bupropion) do I take to quit smoking?
    Follow the prescribing doctor's instructions. Usually, a full course of treatment runs for 9 weeks, including the first two weeks while still smoking (prior to the Target Stop Smoking Date.)
  • What is the mechanism of action of bupropion?
    Research data shows that bupropion acts by interfering with norepinephrine and dopamine reuptake. These two neurotransmitters are involved in the reaction to nicotine that produce cravings for the substance. It also reduces the stimulant effects of nicotine on the nicotinic acetylecholine receptors in the brain.
  • How long does it take for bupropion to work for smoking cessation?
    Tobacco cravings should begin to decrease when the body has enough bupropion to start easing the symptoms of nicotine withdrawal. This should begin after the first week of treatment with Zyban while still smoking.
  • Can I drink alcohol which taking Zyban?
    Follow your doctor's advice. Some people are more sensitive to alcohol which taking Zyban and should reduce their alcohol intake for the nine weeks of treatment or try to drink as little as possible.
  • Are Zyban and Wellbutrin XR the same?
    Zyban and Wellbutrin XR both contain the generic compound bupropion hydrochloride. The difference is in the strength and format. Zyban comes only in one dose (150 mg) of sustained-release bupropion specifically designed to reduce nicotine cravings. Wellbutrin XR comes in two strengths (150 mg and 300 mg) of the extended-release form, which releases more slowly into the blood.

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