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For visual reference only; actual product may vary

  • US Name:

    Saphris

  • Alternative Names:

    Saphris

  • Active Ingredients:

    Asenapine as Maleate

  • Brand Manufacturer:

    Lundbeck

  • Manufacturer Location:

    Ireland

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  • Click here to view Product Insert

Saphris *

For visual reference only; actual product may vary

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Saphris (asenapine) is an atypical antipsychotic medication prescribed for adults. It is used to treat schizophrenia and to manage manic or mixed episodes associated with bipolar I disorder, helping to stabilize mood.

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What is Saphris?

Saphris is an atypical antipsychotic medication containing the active ingredient asenapine. It is primarily prescribed to adults for the treatment of schizophrenia. Saphris is also used to manage the acute symptoms of manic or mixed episodes related to bipolar I disorder. For bipolar disorder, it can be used on its own (monotherapy) or with other medications like lithium or valproate (adjunctive therapy). This medication works to help control symptoms and improve mental stability. It comes as a sublingual tablet that dissolves under the tongue.

How does Saphris work?

Saphris works by changing the effects of chemicals in the brain. The exact way it works is not fully understood. However, it is known to affect the activity of dopamine and serotonin. These are natural substances in the brain called neurotransmitters. Dopamine and serotonin are involved in regulating mood, thinking, and behavior. By blocking the receptors for these chemicals, Saphris helps to rebalance them. This action can reduce psychotic symptoms like hallucinations and delusions. It also helps to stabilize mood in people with bipolar disorder.

Who is Saphris for?

Saphris is intended for use by adults diagnosed with specific mental health conditions. It is approved for adult patients who require treatment for schizophrenia. This medication helps manage the ongoing symptoms of this condition. Saphris is also for adults experiencing acute manic or mixed episodes of bipolar I disorder. Patients can take it alone or with another mood stabilizer. A doctor will determine if this medication is appropriate. It is not approved for use in children for any condition. It is also not for elderly patients with dementia-related psychosis.

Dosage and administration

Saphris should be taken exactly as prescribed by your healthcare provider. The medication is a sublingual tablet, meaning it must be placed under the tongue. You should allow it to dissolve completely. Do not chew, crush, or swallow the tablet whole. Water, food, or other liquids should not be consumed for 10 minutes after taking the dose. The dosage depends on the condition being treated and the patient’s response. For schizophrenia, treatment often starts with a specific dose taken twice daily. The dose may be adjusted by your doctor. Always follow your doctor’s instructions for the best results.

Side effects

Saphris can cause side effects, though not everyone will experience them. Common side effects often include drowsiness, dizziness, and a numb or tingling feeling in the mouth. Some people may also feel restless or have trouble sleeping. Other effects might include dry mouth, constipation, or weight gain. More serious side effects can also occur. These may involve muscle or nervous system problems, like tremors, stiffness, or uncontrolled movements. It is important to contact your doctor right away if you experience severe muscle spasms, agitation, or trouble swallowing. Seek immediate medical help for any signs of a severe allergic reaction.

Why buy from IsraelPharm?

IsraelPharm is a trusted source for brand-name medications like Saphris. We are committed to providing affordable access to the treatments you need. Our prices are competitive, helping you save money on your prescription costs. We ensure that all our products are authentic and sourced from reliable manufacturers. Our ordering process is simple and secure. We offer discreet and efficient shipping directly to your door. Our customer service team is available to help with any questions. Choose IsraelPharm for a reliable and cost-effective way to manage your health.

Saphris may cause side effects. Tell your doctor if you experience any adverse reactions. Not all possible side effects are listed here.

Common Side Effects

  • Drowsiness or dizziness
  • Numbness or tingling of the mouth
  • Dry mouth
  • Constipation or upset stomach
  • Restlessness or sleep problems (insomnia)
  • Weight gain

Serious Side Effects (Contact your doctor immediately)

  • Anxiety, agitation, or jitteriness
  • Shaking (tremor) or a shuffling walk
  • Drooling or trouble swallowing
  • Stiff muscles or severe muscle spasms (e.g., twisting neck, arching back)
  • A mask-like facial expression
  • Signs of a serious allergic reaction

Saphris (asenapine) is an atypical antipsychotic indicated for the following uses in adults:

  • Schizophrenia: For the acute and maintenance treatment of schizophrenia.
  • Bipolar I Disorder (Monotherapy): For the acute treatment of manic or mixed episodes.
  • Bipolar I Disorder (Adjunctive Therapy): For use with lithium or valproate for the acute treatment of manic or mixed episodes.

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