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For visual reference only; actual product may vary

  • US Name:

    Opsumit

  • Alternative Names:

    Opsumit

  • Active Ingredients:

    Macitentan

  • Brand Manufacturer:

  • Manufacturer Location:

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Opsumit *

For visual reference only; actual product may vary

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Opsumit (macitentan) is a daily prescription medicine for pulmonary arterial hypertension (PAH). It helps improve exercise ability and delay disease progression. By relaxing pulmonary arteries, it reduces strain on the heart, helping to lower the risk of PAH-related hospitalization for a better quality of life.

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Opsumit Brand 10mg
30 Tablets
-
+
Our price:
$2,900.00

*Please note all prices are in US dollars

What is Opsumit?

Opsumit is a prescription oral medication used to treat pulmonary arterial hypertension (PAH) in adults. Its generic name is macitentan. This treatment is specifically for patients with WHO Group I PAH. Opsumit helps slow down the worsening of the disease. It also reduces the risk of being hospitalized due to PAH. By managing symptoms, it can improve your ability to be physically active. It is not a cure but a long-term therapy.

How does Opsumit work?

Opsumit works by blocking the effects of endothelin, a substance in the body that causes blood vessels to narrow. As a dual endothelin receptor antagonist, it targets and blocks two key receptors (ET-A and ET-B). This action helps relax the blood vessels in the lungs. Relaxing these vessels decreases the high blood pressure in the pulmonary arteries. This process, known as vasodilation, reduces the strain on the right side of the heart. It also helps prevent harmful changes in the structure of the arteries.

Who is Opsumit for?

Opsumit is for adults diagnosed with pulmonary arterial hypertension, specifically WHO Group I. This group includes patients whose PAH is not caused by other underlying heart or lung diseases. The medication is prescribed to help delay the progression of the disease. It aims to improve exercise capacity and general quality of life. Patients who want to lower their chances of hospitalization for PAH may benefit. It is not for pregnant women due to the risk of serious birth defects.

Dosage and administration

Opsumit is prescribed as a 10 mg tablet to be taken once per day. You can take the tablet with or without food. It is important to swallow the tablet whole. Do not crush, split, or chew it. Try to take your dose at the same time each day to maintain stable levels of the medicine in your body. If you miss a dose, take it as soon as you remember on the same day. Never take a double dose to make up for a missed one.

Side effects

Opsumit may cause side effects, though not everyone experiences them. Common side effects include headache, stuffy nose, sore throat, and bronchitis. Some patients may also develop anemia, which is a low red blood cell count. Your doctor will monitor this with blood tests. More serious side effects can occur. These include liver problems and fluid retention. Seek medical help right away if you notice yellowing skin, dark urine, or unusual swelling. This medication can cause serious birth defects. It must not be taken during pregnancy.

Why buy from IsraelPharm?

Opsumit is a crucial medication for managing a serious condition, and IsraelPharm provides a reliable, cost-effective source. We are committed to patient safety and satisfaction. Our licensed pharmacists are available to answer your questions and provide support. We ensure every medication is authentic and sourced from legitimate suppliers. By ordering from IsraelPharm, you get convenient access to your prescribed treatment at competitive prices. We handle your health with the professionalism and care you deserve, delivering your medication discreetly to your door.

Common side effects of Opsumit can include:

  • Headache
  • Stuffy or runny nose and sore throat (nasopharyngitis)
  • Bronchitis
  • Urinary tract infection
  • Flu-like symptoms
  • Low red blood cell count (anemia)

Seek immediate medical attention if you experience signs of a serious reaction, such as:

  • Symptoms of liver problems (yellowing skin or eyes, dark urine, right-side stomach pain)
  • Swelling of the face, tongue, or throat
  • Difficulty breathing or wheezing
  • Severe skin rash, blistering, or peeling
  • Signs of significant fluid retention (swelling in ankles or legs)

Opsumit is an FDA-approved prescription medication used for the treatment of:

  • Pulmonary Arterial Hypertension (PAH): Indicated for patients classified as WHO Group I to delay disease progression and reduce the risk of PAH-related hospitalization.

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