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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Ocrevus (ocrelizumab) is a prescription infusion therapy for adults with relapsing or primary progressive forms of multiple sclerosis (MS). It targets specific immune cells to help slow disease progression. This is a cold chain product requiring special shipping.
| Ocrevus Brand | 300mg/10mL 1 Vial |
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Our price: $9,000.00 |
Ocrevus is a prescription medication used to treat adults with relapsing forms of multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS). It belongs to a class of drugs called monoclonal antibodies. Ocrevus helps to slow the progression of disability and reduce the frequency of relapses. Its active ingredient is ocrelizumab. This medication is administered through an intravenous (IV) infusion. A healthcare professional must oversee the treatment. It is designed to be a long-term therapy for managing MS.
Ocrevus works by targeting a specific type of immune cell called a CD20-positive B cell. In multiple sclerosis, these B cells are thought to contribute to nerve damage. This damage leads to the symptoms and progression of the disease. Ocrevus binds to these B cells and causes them to be depleted from the bloodstream. By reducing the number of these harmful cells, it helps to decrease inflammation. This action protects the nerves from further damage. It ultimately slows down the worsening of MS symptoms and reduces flare-ups.
Ocrevus is for adults diagnosed with specific types of multiple sclerosis. This includes relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS). Together, these are known as relapsing forms of MS (RMS). It is also the first and only therapy approved for primary progressive MS (PPMS). Patients considering this treatment should have a confirmed diagnosis from a neurologist. It is intended for individuals seeking to slow disease progression and reduce relapse rates. This medication is not approved for use in children.
Ocrevus dosage and administration is done via intravenous (IV) infusion by a healthcare provider. The first dose is given as two separate infusions, two weeks apart. After the initial dose, you will receive one single infusion every six months. Each infusion session takes several hours to complete. Before the infusion, you will likely receive other medications. These can include a corticosteroid, an antihistamine, and a fever reducer. This helps to lower the chance of infusion reactions. The entire process happens in a clinic or hospital setting.
Ocrevus may cause side effects, with infusion reactions being the most common. These often happen during or shortly after the infusion. Symptoms can include itching, rash, fever, and headache. Other common side effects may include upper respiratory tract infections. Less common but more serious risks exist. These include an increased risk of infections, such as hepatitis B reactivation. There is also a potential increased risk of certain types of cancer, including breast cancer. Patients should discuss all potential side effects with their doctor before starting treatment.
Buying Ocrevus from IsraelPharm ensures you receive genuine, brand-name medication sourced from authorized distributors. We provide a straightforward and secure online ordering process. Our platform connects you with licensed pharmacies, offering competitive prices on medications. We prioritize patient safety and convenience. Our customer support team is available to assist with your order. We handle every prescription with care, including specialized shipping for cold chain products. Trust us for reliable access to your essential MS treatment.
Like all medicines, Ocrevus can cause side effects, although not everybody gets them. It is important to discuss these with your doctor.
Contact your doctor immediately if you experience signs of a serious reaction or infection.
Ocrevus (ocrelizumab) is used for the treatment of:
Ocrevus is administered as an intravenous (IV) infusion by a healthcare professional in a clinical setting. The first dose is split into two infusions given two weeks apart. Subsequent maintenance doses are given as a single infusion once every six months. Pre-medication is often given to reduce the chance of infusion reactions. The entire process can take several hours to complete.
The most common side effects of Ocrevus are infusion-related reactions. These can include headache, itchy skin, rash, fever, and nausea. Upper respiratory tract infections, like the common cold, are also frequently reported. Most infusion reactions are mild to moderate. Your healthcare provider will monitor you during and after the infusion to manage any reactions that may occur.
Receiving Ocrevus may affect how well vaccines work and your risk of infection. You should not receive live or live-attenuated vaccines, such as the MMR or chickenpox vaccine, while on this treatment. It is recommended to have all necessary vaccines updated at least four to six weeks before starting Ocrevus. Always discuss your vaccination plans with your neurologist to ensure safety.
Ocrevus begins working to deplete specific B cells shortly after the first infusion. However, the clinical benefits, such as a reduction in relapses and a slowing of disability progression, may take several months to become apparent. The effectiveness of Ocrevus is measured over the long term, and it is important to continue with the prescribed treatment schedule for the best results.
Ocrevus is not considered a traditional chemotherapy drug used for cancer. It is a targeted immunotherapy called a monoclonal antibody. While chemotherapy drugs typically kill all rapidly dividing cells, Ocrevus is designed to selectively target and remove specific B cells in the immune system that are involved in the MS disease process. This targeted action helps to reduce side effects compared to non-specific treatments.
If you miss your scheduled Ocrevus infusion, you should contact your doctor or infusion center as soon as possible. It is important to reschedule your appointment to maintain the treatment's effectiveness in managing your MS. Do not wait for your next regularly scheduled appointment six months later. Your healthcare provider will give you instructions on how to proceed.
Ocrevus is not typically associated with hair loss. Hair loss, or alopecia, is not listed as a common side effect in clinical trials for Ocrevus. This side effect is more commonly associated with chemotherapy agents that affect all rapidly growing cells. If you are experiencing unusual hair thinning or loss while on Ocrevus, you should discuss it with your doctor to explore other potential causes.
Ocrevus does not have a direct, well-known interaction with alcohol. However, both alcohol and some Ocrevus side effects, such as headaches or dizziness, can affect your body. It is generally advisable to consume alcohol in moderation. Before your infusion, it’s best to be well-hydrated and avoid alcohol. Always consult your healthcare provider for personalized medical advice regarding alcohol consumption with your treatment plan.
Ocrevus is not recommended for women who are pregnant or trying to become pregnant. There is limited data on its effects on an unborn baby. Women of childbearing potential should use effective contraception while receiving Ocrevus and for at least six months after the last infusion. If you are considering pregnancy, you must discuss a safe family planning strategy with your neurologist.
Ocrevus must be stored under specific refrigerated conditions. This medication requires cold chain handling, meaning it is kept between 2°C to 8°C (36°F to 46°F) and protected from light. It will be shipped in a specialized cooled container to maintain this temperature. A pharmacist or healthcare provider is responsible for its proper storage and preparation before your infusion.
Ocrevus does not cure multiple sclerosis. Currently, there is no cure for MS. However, Ocrevus is a highly effective disease-modifying therapy (DMT) that can significantly slow the progression of disability. It also helps reduce the number and severity of relapses. Its goal is to manage the disease long-term and improve the quality of life for individuals with MS.
During an Ocrevus infusion, a healthcare professional will place an IV line into a vein in your arm. Before the infusion starts, you will receive pre-medications to help prevent a reaction. The Ocrevus medication is then slowly dripped through the IV over several hours. During this time, nurses will monitor you for any signs of an infusion reaction. You will also be monitored for at least an hour after the infusion is complete.
While using Ocrevus, your doctor will likely order regular blood tests. Before starting, and periodically throughout treatment, your blood will be checked for Hepatitis B virus infection. Your doctor may also monitor your blood counts to check the levels of your immune cells, including the B cells that Ocrevus targets. This monitoring helps ensure the treatment is both safe and effective for you.
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