How does NMDA function in relation to dementia?

The NMDA receptor plays a role in plasticity, which includes memory and learning functions. When NMDA receptors are overly activated, it can lead to excitotoxicity and potential harm to neurons believed to contribute to conditions such as dementia.

What are the symptoms of mood swings in Alzheimer's patients?

During the early stages of Alzheimer's, symptoms of mood swings may be seen as an individual struggling to find the right words, feeling frustrated or irritable and also can present as exhibiting unexpected behaviors like refusing to take a bath. Damage to nerve cells in the brain can also make it challenging for Alzheimer's patients to communicate thoughts and carry out tasks without help.

Which neurotransmitter is linked to Alzheimer's disease?

Alzheimer's disease impacts brain cells causing a decrease in the neurotransmitter acetylcholine, that aids transmitting messages between brain cells.

Why are NMDA antagonists utilized for treating Alzheimer's?

While high levels of glutamate can cause neurotoxicity due in part to activation of NMDARs, Ebixa/Memantin (memantine) acts as an antagonist for these receptors by blocking them. This action helps regulate the system and improve function and memory deficits.

Can I drink alcohol while taking memantine?

Doctors advise to avoid alcohol while taking memantine, or cut back on levels of consumption. Alcohol can make dementia symptoms worse, increasing confusion and forgetfulness. Memantine can also increase alcohol's dissociative effects.

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Home / Online Pharmacy / Namenda

For visual reference only; actual product may vary

US Name:

Namenda
Alternative Names:

Ebixa, Memantin
Active Ingredients:

Memantine
Brand Manufacturer:

Lundbeck
Manufacturer Location:

Denmark
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Namenda ^*

For visual reference only; actual product may vary

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Namenda (Ebixa) is intended for the treatment of moderate to severe Alzheimer’s disease.

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Memantine Generic	20mg 28 Tablets	- Namenda – Generic, Memantine, 20mg, 28, Tablets, 555555, UK Generic, 2722 + 0	Our price: $22.00
Ebixa Brand	10mg 56 Tablets	- Namenda – Brand, Ebixa, 10mg, 56, Tablets, 59111, Lundbeck, 385 + 0	Our price: $84.00
Memantine Generic	10mg 28 Tablets	- Namenda – Generic, Memantine, 10mg, 28, Tablets, 555555, UK Generic, 2721 + 0	Our price: $22.00
Memantin Generic	10mg 56 Tablets	- Namenda – Generic, Memantin, 10mg, 56, Tablets, 83518, Teva, 1644 + 0	Our price: $69.00

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Description
Side Effects
Indications
FAQ
Video

Ebixa / Namenda (memantine) belongs to the group of medicines known as NMDA receptor antagonists and is prescribed to treat moderate to severe Alzheimer’s disease.

Ebixa is not recommended for children and adolescents under the age of 18 years.

Dosage

The doctor will determine the dosage regimen. The usual dosage for adults and elderly patients is 20 mg daily. To reduce the risk of side effects, this dose is achieved gradually, starting at 5 mg (half a tablet) per day in the first week, then increasing by 5 mg each week for three weeks until the full dose is reached.

If a higher dosage is taken in error, contact a doctor or seek medical help. Taking an overdose will usually not result in any harm but may cause increased side effects. If a child swallowed the medicine by mistake, refer immediately to the physician or a hospital emergency room and bring the package of medicine with.

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

The observed side effects are mild to moderate. They include:

headache
sleepiness
constipation
dizziness
balance disorders
shortness of breath
high blood pressure.

If these or other unlisted symptoms persist or worsen, talk to a doctor or pharmacist.

There is evidence that memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain caused by excessive activity of a natural body chemical called glutamate. The brain contains N-methyl-D-aspartate (NMDA) receptors involved in transmitting nerve signals that are important in learning and memory.

Memantine blocks excessive glutamate activity on the NMDA receptor but still allows the normal activation of these receptors when the brain forms a memory.

The NMDA receptor plays a role in plasticity, which includes memory and learning functions. When NMDA receptors are overly activated, it can lead to excitotoxicity and potential harm to neurons believed to contribute to conditions such as dementia.
During the early stages of Alzheimer's, symptoms of mood swings may be seen as an individual struggling to find the right words, feeling frustrated or irritable and also can present as exhibiting unexpected behaviors like refusing to take a bath. Damage to nerve cells in the brain can also make it challenging for Alzheimer's patients to communicate thoughts and carry out tasks without help.

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