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For visual reference only; actual product may vary

  • US Name:

    Mektovi

  • Alternative Names:

    Mektovi

  • Active Ingredients:

    Binimetinib

  • Brand Manufacturer:

    Pfizer

  • Manufacturer Location:

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Mektovi *

For visual reference only; actual product may vary

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Mektovi (binimetinib) is a targeted therapy medication. It is used with another drug to treat a type of skin cancer called melanoma. This treatment is for melanoma with a specific gene change (BRAF V600 mutation).

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Mektovi Brand 15mg
180 Tablets
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+
Our price:
$9,500.00

*Please note all prices are in US dollars

What is Mektovi?

Mektovi is a prescription medication used in the field of oncology. It is classified as a targeted therapy drug for a specific type of skin cancer. This cancer is known as melanoma. Mektovi is specifically for melanoma that has a certain genetic marker. This marker is the BRAF V600E or V600K mutation. It is always given in combination with another medication called encorafenib. This combination approach targets the cancer cells more effectively. Mektovi is not used for melanoma that does not have the BRAF gene mutation.

How does Mektovi work?

Mektovi works by blocking specific proteins in the body that signal cancer cells to grow. Its active ingredient, binimetinib, is a MEK inhibitor. MEK proteins are part of a larger signaling pathway. When this pathway is overactive due to a BRAF mutation, it causes cancer cells to multiply uncontrollably. Mektovi stops this process at the MEK stage. By doing so, it helps to slow or stop the growth and spread of the melanoma cells. It is used with a BRAF inhibitor for a more complete blockade of this pathway. This dual action is more effective than using one drug alone.

Who is Mektovi for?

Mektovi is for adults diagnosed with a specific form of advanced skin cancer. This includes melanoma that is unresectable (cannot be removed by surgery) or metastatic (has spread to other parts of the body). A critical requirement is that the patient’s tumor must have a BRAF V600E or V600K mutation. Your oncologist will perform a test to confirm this genetic marker before prescribing the medication. Mektovi is not intended for all skin cancer patients. It is only for those who fit this specific genetic profile. The treatment is always part of a combination therapy.

Dosage and administration

Mektovi dosage and administration should be strictly followed as prescribed by your doctor. The tablets are taken orally, twice a day. They should be swallowed whole with water. You can take Mektovi with or without food. It is important to take the doses approximately 12 hours apart. Your oncologist will determine the exact dose based on your medical condition and response to treatment. Do not change your dose or stop taking the medication without consulting your doctor. If you miss a dose, ask your healthcare provider for instructions. Consistency is key for the medication to be effective.

Side effects

Mektovi can cause several side effects, ranging from mild to severe. Common side effects often include fatigue, nausea, diarrhea, and vomiting. Some people may also experience abdominal pain or a skin rash. More serious side effects require immediate medical attention. These can include problems with your heart, such as a decreased ability to pump blood. Other serious risks involve blood clots in your arms or legs, lung problems, and eye issues. Muscle damage (rhabdomyolysis) is another rare but serious possibility. Always report any unusual symptoms to your healthcare provider right away.

Why buy from IsraelPharm?

IsraelPharm provides a reliable and affordable option for your important medications. We source Mektovi and other essential drugs directly from trusted manufacturers. This allows us to offer significant savings without compromising on quality or safety. Our streamlined online ordering process is simple and secure. We are committed to making your treatment more accessible. Our customer service team is available to assist you. Choose IsraelPharm for competitive pricing and dependable international delivery of your prescription medications.

Like all medications, Mektovi may cause side effects. Not everyone will experience them.

Common Side Effects:

  • Fatigue or weakness
  • Nausea and vomiting
  • Diarrhea
  • Skin rash
  • Abdominal pain
  • Swelling in the arms or legs (peripheral edema)

Serious Side Effects (require immediate medical attention):

  • Heart problems (cardiomyopathy)
  • Blood clots (venous thromboembolism)
  • Eye problems (retinal detachment)
  • Lung or breathing issues
  • Liver problems
  • Muscle damage (rhabdomyolysis)
  • Bleeding

Mektovi is primarily used for the treatment of:

  • Unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with encorafenib.

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