The most common side effect is diarrhea. It usually begins within the first two weeks of using Linzess as a treatment. If severe diarrhea is experienced while taking this treatment, it is advised to stop taking it and contact a doctor or healthcare provider.

Other common side effects may include: 

• Gas
• Abdominal pain 
• A feeling of fullness, swelling, or pressure in the abdomen

Linzess is indicated for the treatment of different types of constipation, including irritable bowel syndrome with constipation, chronic idiopathic constipation, and functional constipation in pediatric patients 6-17 years of age. 

Linzess is an oral tablet taken once daily on an empty stomach (30 minutes after food intake). If taken with applesauce or water, it is advised to refrain from eating 30 minutes after use.