Letairis ^*

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.

The information leaflet that comes with the medication includes full information about the possible side effects. Be sure to read and understand these, and if there are any questions, discuss these with a healthcare provider or pharmacist before starting treatment.

Cautions

If a sudden allergic reaction (anaphylaxis) occurs shortly after taking Letairis, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

Pregnant women should not be using Letairis unless this has been discussed with a healthcare provider, as it might harm the unborn baby or pose a risk of miscarriage. For this reason, women planning to become pregnant should use appropriate birth control measures during the treatment and one month after taking the last dose of Letairis.

Letairis may pass into breast milk, and mothers should consult with a doctor if already feeding or planning to feed an infant.

Most people who use Letairis do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include:

• Swelling of hands, legs, ankles, and feet
• Nasal congestion or sinus irritation
• Hot flashes or facial redness

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider.

Letairis is approved for the treatment of pulmonary arterial hypertension (PAH), a rare condition where the arteries in the lungs become narrow and stiff. This narrowing increases the pressure inside the pulmonary arteries, forcing the heart to work harder to pump blood through the lungs. Over time, PAH can cause shortness of breath, tiredness, chest pain, swelling in the ankles or legs, and reduced ability to exercise.

By blocking endothelin‑A receptors, Letairis helps these blood vessels relax and widen. This lowers pulmonary blood pressure, helps ease strain on the heart, and can improve exercise capacity.

When taken with Cialis, Letairis may further lower the chance of PAH worsening or leading to hospitalization.

Letairis is not approved for any other conditions. It is not known to be safe or effective for children, and it must not be used in anyone who is pregnant because of the high risk of birth defects.

Because of these serious risks, the medication is dispensed only through a restricted safety program that ensures patients understand the pregnancy testing and birth control requirements before starting therapy.