How long does granisetron stay in the body?

After taking it by mouth, granisetron can stay in the body for about 6 hours on average and up to 14 hours in some people. About 60% of it enters the bloodstream and 65% binds to proteins in blood.

Why is Kytril effective for chemo‑related sickness?

Chemotherapy often releases serotonin in the intestines, which triggers nausea. Kytril blocks these signals before and after treatment, helping patients feel less sick and more comfortable.

Does Kytril help with radiation‑related nausea?

Yes. Radiation can also cause serotonin release and discomfort. Kytril is used in adults to prevent and treat this kind of nausea when given before and during radiotherapy.

What is a 5‑HT₃ receptor antagonist?

This group of medicines blocks serotonin activity in areas of the gut and brain that cause nausea and vomiting. Well-known drugs in this group include granisetron, ondansetron, and tropisetron.

Are there special risks with 5‑HT₃ receptor antagonists?

Most side effects are mild, like headache and constipation. Rarely, it can cause changes in heart rhythm or serious reactions when mixed with certain antidepressants. Medical attention is important if unusual symptoms appear.

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Home / Online Pharmacy / Kytril

For visual reference only; actual product may vary

US Name:

Kytril
Alternative Names:

Kytril
Active Ingredients:

Granisetron
Brand Manufacturer:

Roche
Manufacturer Location:

Switzerland
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Kytril ^*

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Kytril is prescribed to treat nausea and vomiting caused by chemotherapy or radiation therapy.

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Kytril Brand	1mg 10 Tablets	- Kytril – Brand, Kytril, 1mg, 10, Tablets, 9084, Roche, 310 + 0	Our price: $136.00

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Description
Side Effects
Indications
FAQ
Video

Kytril (generic name: granisetron) is a 5‑HT₃ receptor antagonist, a type of anti‑emetic medicine that helps prevent and treat nausea and vomiting caused by cancer treatments. It works by blocking signals sent by a chemical called serotonin in both the gut and the brain. Kytril tablets are only for adult use and are available in 1 mg film-coated tablets. It was approved by the FDA in 1995 and is included on the World Health Organization’s List of Essential Medicines. The tablets are triangular, white to off‑white, and marked “K1”. It has clear effects in treatments like chemotherapy without affecting other body systems.

Dosage

Always follow the instructions printed on the box label. Kytril tablets are usually taken about one hour before chemotherapy or radiotherapy starts. Adults take either two 1 mg tablets once daily or one 1 mg tablet twice daily. This schedule continues for up to one week after therapy. Tablets should be swallowed whole with water and may be taken with or without food.

Storage

Tablets should be stored below 25 °C (72°F) in their original packaging to guard against moisture. For more information, read our article on drug storage.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.

Read the information leaflet that comes with the medication.

If a sudden allergic reaction (anaphylaxis) occurs shortly after taking Kytril, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

Most people who use Kytril do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include headache, constipation, and insomnia.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Kytril is prescribed for:

Chemotherapy‑induced nausea and vomiting (CINV)
Kytril is used to prevent and treat nausea and vomiting in adults receiving chemotherapy. These treatments often release serotonin in the gut, leading to queasiness and vomiting. Kytril blocks those signals and helps reduce discomfort and loss of appetite.
Radiotherapy‑induced nausea and vomiting (RINV)
Adults undergoing radiotherapy, such as treatment to the abdomen or whole body, can also feel sick. Kytril helps prevent and reduce these symptoms when taken before and after treatment.

After taking it by mouth, granisetron can stay in the body for about 6 hours on average and up to 14 hours in some people. About 60% of it enters the bloodstream and 65% binds to proteins in blood.

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