For visual reference only; actual product may vary
For visual reference only; actual product may vary
Kisqali (ribociclib) is a targeted therapy used to treat certain types of breast cancer. It is prescribed for adults with HR-positive, HER2-negative advanced or metastatic breast cancer. Kisqali works by slowing the growth of cancer cells and is often used in combination with other endocrine therapies.
| Kisqali Brand | 200mg 42 Tablets |
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Our price: $2,904.00 |
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| Kisqali Brand | 200mg 63 Tablets |
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Our price: $4,356.00 |
Kisqali is a prescription medication used to treat certain types of breast cancer in adults. This targeted therapy is specifically for cancers that are hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative. Kisqali is designed for advanced or metastatic breast cancer, meaning cancer that has spread beyond the breast to other parts of the body. It belongs to a class of drugs known as CDK4/6 inhibitors. These drugs work by interrupting the process of cancer cell division and growth.
Kisqali works by blocking the activity of proteins called cyclin-dependent kinases 4 and 6 (CDK4/6). These proteins are essential for the growth and division of cells. In hormone receptor-positive breast cancer, these proteins are often overactive, which fuels the rapid growth of cancer cells. By inhibiting CDK4/6, Kisqali helps to slow down or stop the proliferation of these cancer cells. This action makes it an effective endocrine-based therapy. It is typically used with an aromatase inhibitor or fulvestrant to further block hormone signals that encourage cancer growth.
Kisqali is for adults diagnosed with advanced or metastatic breast cancer that is HR-positive and HER2-negative. It is a suitable first-line treatment for postmenopausal women when combined with an aromatase inhibitor. Additionally, Kisqali can be used with fulvestrant as an initial treatment or for patients whose disease has progressed. This combination with fulvestrant is approved for both postmenopausal women and for men. Your oncologist will perform tests on the cancer cells to determine if Kisqali is an appropriate treatment for your specific type of breast cancer.
Kisqali dosage is determined by a healthcare professional based on the patient’s condition. The standard recommended dose is 600 mg of Kisqali, taken as three 200 mg tablets once daily. This is typically done for 21 consecutive days, which is followed by a 7-day break from treatment. This 28-day period completes one full treatment cycle. Kisqali should be taken at approximately the same time each day, with or without food. It is critical to follow your doctor’s instructions precisely and not to alter the dose or schedule without medical advice.
Kisqali may cause side effects, though not everyone will experience them. Your doctor will weigh the benefits against the potential risks before prescribing it. It is important to discuss any concerns with your healthcare provider. Common side effects can include:
This is not a complete list of all possible side effects. Contact your doctor immediately if you experience persistent symptoms, signs of infection, or any other unusual effects.
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Most individuals using Kisqali do not experience severe side effects. A doctor prescribes this medication believing its benefits outweigh the risks. However, some common side effects may occur.
Not all potential side effects are listed here. If you experience these symptoms and they persist or worsen, or if you notice other unlisted effects, please consult your doctor or pharmacist for guidance.
Kisqali is indicated for the treatment of adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.
It is used in combination with an aromatase inhibitor as initial endocrine-based therapy. It is also used in combination with fulvestrant as initial endocrine-based therapy or following disease progression on endocrine therapy in postmenopausal women or in men.
Kisqali is a targeted cancer drug used to treat a specific type of breast cancer in adults. It is prescribed for advanced or metastatic breast cancer that is hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative. Kisqali helps to slow or stop the growth of cancer cells and is usually given in combination with another hormone therapy, such as an aromatase inhibitor or fulvestrant.
Kisqali is taken orally as tablets, once per day, at about the same time each day. The usual regimen involves taking the tablets for 21 days in a row, followed by a 7-day break where you do not take the medication. This completes a 28-day cycle. It is important to swallow the tablets whole and not to chew, crush, or split them before swallowing. Always follow your oncologist's specific instructions.
Yes, Kisqali tablets can be taken either with or without food. Taking it with a meal does not significantly affect how the medication is absorbed by your body. If you experience nausea, taking Kisqali with a small meal or snack may help to reduce this side effect. Consistency is key, so try to take it in a similar manner each day as part of your routine.
If you miss a dose of Kisqali, you should skip the missed dose for that day. Simply wait and take your next scheduled dose at the regular time on the following day. Do not take two doses at the same time or an extra dose to make up for the one you missed. This could increase your risk of experiencing serious side effects. If you vomit after taking a dose, do not take another one.
Kisqali can cause hair to thin or fall out, which is a side effect known as alopecia. While this is one of the more common side effects reported by patients taking the medication, it does not happen to everyone. The extent of hair loss can vary from mild thinning to more significant loss. This effect is usually temporary, and hair typically begins to grow back after the treatment cycle is adjusted or completed.
Kisqali should be stored in its original packaging at room temperature, below 86°F (30°C). Keep the medication in a dry place away from moisture and direct heat. It is very important to store Kisqali in a location that is safely out of the reach of children and pets. Do not use any tablets that have expired or if the packaging appears damaged before you open it.
You should not consume grapefruit or grapefruit juice while taking Kisqali. Grapefruit can interfere with how your body metabolizes the medication, leading to higher levels of the drug in your bloodstream. This significantly increases your risk of developing serious side effects, such as heart and liver problems. Always check with your doctor or pharmacist about any other foods or supplements to avoid during your treatment.
Kisqali can cause harm to an unborn baby, so it is not safe to become pregnant during treatment. Women who are able to become pregnant should use effective birth control while taking Kisqali and for at least three weeks after the final dose. Your doctor will likely require a negative pregnancy test before starting treatment. You should discuss effective contraception methods for you and your partner with your healthcare provider.
Yes, Kisqali is approved for use in men for treating HR-positive, HER2-negative advanced or metastatic breast cancer. When prescribed for men, it is given in combination with a medication called fulvestrant. The dosage and treatment cycle are generally the same for men as they are for postmenopausal women. Men with this specific type of breast cancer should consult an oncologist to see if this combination therapy is right for them.
Before you start Kisqali, your doctor will order several important tests to ensure it is safe for you. These typically include blood tests to check your liver function and your blood cell counts. Your doctor will also perform an electrocardiogram (ECG or EKG) to check your heart's electrical activity. These tests will be repeated regularly throughout your treatment to monitor for potential side effects, such as liver inflammation or heart rhythm changes.
Kisqali is not considered a cure for breast cancer, but it is a highly effective treatment for managing it. For patients with advanced or metastatic HR-positive, HER2-negative breast cancer, Kisqali can significantly slow down the progression of the disease and extend the time before the cancer worsens. The goal of the therapy is to control cancer growth, manage symptoms, and help patients maintain a good quality of life for as long as possible.
You will know Kisqali is working based on regular evaluations from your oncologist. Your doctor will use a combination of methods to monitor your progress. These include imaging scans like CT, PET, or bone scans to see if tumors are shrinking or stable. They will also monitor tumor markers in your blood and assess your overall symptoms and how you are feeling. These regular check-ups determine the effectiveness of the treatment.
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