Intrarosa ^*

Intrarosa contains the active ingredient prasterone. Prasterone is a synthetically made version of dehydroepiandrosterone (DHEA), a substance naturally found in the body. Unlike direct estrogen therapies, prasterone is an inactive compound. It is converted into active estrogens and androgens only inside the cells of the vaginal wall. This local action helps to minimize the amount of hormones circulating throughout the rest of your body.

Intrarosa may begin to relieve symptoms of painful intercourse within a few weeks of starting treatment. However, some studies show that significant improvement can take up to 12 weeks of consistent, daily use. The time it takes to see results can vary from person to person. It is important to use the medication every day as prescribed by your doctor to achieve the best outcome and effectively manage your symptoms.

Intrarosa is considered a local hormone therapy, but it differs from traditional systemic HRT. The active ingredient, prasterone, is converted to hormones directly within the vaginal tissue. This means the effects are concentrated where they are needed, with minimal absorption into the bloodstream. This makes it a different approach compared to systemic HRT pills or patches that circulate hormones throughout the entire body.

If you miss a dose of Intrarosa, you should insert it as soon as you remember. However, if it is almost time for your next scheduled dose, just skip the missed dose. Do not use a double dose to make up for the one you missed. Using extra medication will not improve symptoms faster and may increase the risk of side effects. Maintain your regular once-daily schedule for the best results.

Intrarosa can cause vaginal discharge, and it is the most common side effect reported. The insert is made from a hard fat base that melts at body temperature to release the medication. This melted base can result in a discharge. It is a normal part of the treatment process. Using a panty liner at night or in the morning can help manage this effect. If the discharge has a foul odor or color, contact your doctor.

Intrarosa should be stored at room temperature, between 68°F and 77°F (20°C and 25°C). It can be kept in temperatures from 59°F to 86°F (15°C to 30°C) for short periods. It is important to keep the inserts in their original packaging until you are ready to use one. Do not store them in the bathroom where heat and humidity are high, and keep them away from direct light and out of reach of children.

Intrarosa inserts contain a hard fat base that can weaken latex condoms. It is recommended to avoid using latex condoms for contraception or protection from sexually transmitted infections while using this medication. If you need to use a condom, choose one made from non-latex materials like polyurethane or polyisoprene. Always discuss safe sex practices and contraception with your healthcare provider to find the best option for you.

Intrarosa is not commonly associated with weight gain. Clinical studies for the medication did not show weight gain as a frequent side effect. The treatment works locally in the vagina, and very little of the active ingredient is absorbed into the rest of the body. This localization helps to prevent systemic side effects that are sometimes seen with other hormone therapies. If you experience unexpected weight changes, discuss them with your doctor.

Yes, you can have a Pap smear, but Intrarosa is known to sometimes cause an abnormal result. It is very important that you inform your doctor and the pathology laboratory that you are using Intrarosa before you have the test. This information allows them to correctly interpret the results of your Pap smear. Your doctor may advise you to stop using the medication for a short period before the test.

Intrarosa is not recommended for women with a current or past history of breast cancer. Although it works locally, there is not enough long-term data to confirm its safety in this population. You must discuss your full medical history, especially any history of cancer, with your healthcare provider. They will determine if Intrarosa is a safe and appropriate treatment choice for you based on your individual risks and health status.

Intrarosa can be used by women with a uterus. Since Intrarosa works locally in the vagina with minimal systemic absorption, a progestin is not required to protect the uterine lining. This is different from systemic estrogen therapies, which can stimulate the growth of the endometrium and increase cancer risk if taken without a progestin by women with a uterus. Always follow your doctor’s recommendations for your specific situation.

The Intrarosa insert is designed to melt inside the vagina after it is inserted at bedtime. It is unlikely to fall out if it has been inserted correctly. However, if you find that it does fall out and is still whole, you can re-insert it. If it falls out in the toilet, throw it away and use a new insert. Ensure you are inserting it high enough into the vagina to help it stay in place comfortably overnight.

Intrarosa is recommended to be used at bedtime. This helps the insert stay in the vagina for a prolonged period, allowing the medication to be fully absorbed while you are lying down. Using it at night also minimizes any messiness from the discharge that occurs when the base melts. Following this once-daily schedule consistently is the best way to ensure the medication works effectively to relieve your symptoms.