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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Imuran (Azathioprine) is an immunosuppressant medication. It works by weakening the body’s immune system to help prevent rejection of a transplanted organ, like a kidney. Imuran is also prescribed to manage the symptoms of severe active rheumatoid arthritis and other autoimmune conditions.
| Imuran Brand | 25mg 100 Tablets |
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Our price: $54.00 |
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| Imuran Brand | 50mg 100 Tablets |
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Our price: $46.00 |
 Immune Pack | 30 Pouches 1 Pouch a Day | –+ | Our price: $59.50 | |
 Stress Pack | 30 Pouches 1 Pouch a Day | –+ | Our price: $63.75 |
Imuran is an immunosuppressant medication containing the active ingredient Azathioprine. It is prescribed to prevent the body from rejecting a new organ after a transplant surgery. Specifically, it helps stop the immune system from attacking the new kidney. Imuran is also used to treat severe, active rheumatoid arthritis in adults. It can help reduce joint pain and swelling. The medication belongs to a class of drugs known as purine antagonists. It has been a trusted treatment for many years. It is manufactured by GlaxoSmithKline (GSK). Your doctor may prescribe it when other treatments for rheumatoid arthritis have not worked well enough. It is also used for other autoimmune conditions like Crohn’s disease or lupus in some cases.
Imuran works by weakening the body’s natural defense system, also called the immune system. This action is very important in preventing organ transplant rejection. The immune system normally identifies and attacks foreign invaders like bacteria. After a transplant, it can see the new organ as a foreign object. Imuran suppresses this immune response. It specifically interferes with the production of new DNA and RNA in growing cells. It targets fast-dividing cells like the white blood cells that cause rejection. By reducing the activity of these immune cells, Imuran helps your body accept the new organ. For rheumatoid arthritis, it reduces the autoimmune activity that causes joint inflammation.
Imuran is for patients who have received a kidney transplant to prevent organ rejection. It is also for adults with severe, active rheumatoid arthritis who have not responded to other medications. Patients with certain autoimmune diseases like Crohn’s disease or lupus might also be prescribed Imuran. A doctor will determine if this medication is the right choice for you. It is typically used as part of a combination therapy, especially after a transplant. For rheumatoid arthritis, it may be used alone or with other drugs. It is not a first-line therapy for arthritis. Instead, it is reserved for more serious cases that are difficult to manage.
Imuran dosage depends on your medical condition, body weight, and response to treatment. Your doctor will calculate the precise dose for you. Imuran is taken orally as a tablet, usually once or twice a day. You can take it with food or milk to reduce stomach upset. It is very important to take this medication exactly as prescribed by your doctor. Do not change your dose or stop taking it without your doctor’s approval. The dose may need to be adjusted over time based on blood tests. These tests help ensure you are getting the right amount of medicine. Regular monitoring is a key part of treatment with Imuran to ensure safety and effectiveness.
Imuran may cause side effects, with the most common being stomach upset, nausea, and vomiting. These often decrease as your body adjusts to the medication. A more serious side effect is an increased risk of infection. This is because Imuran weakens your immune system. You should report any signs of infection like fever, sore throat, or chills to your doctor immediately. Other possible side effects include loss of appetite, hair loss, and mouth sores. In rare cases, it can affect the liver or blood cell counts. Your doctor will monitor for these effects with regular blood tests. Seek medical attention for unusual bleeding, bruising, or severe fatigue.
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Imuran may cause side effects. Tell your doctor if you experience any of these. Common side effects include:
More serious side effects require immediate medical attention. These can include:
Imuran does not work immediately for conditions like rheumatoid arthritis. It may take 6 to 12 weeks of consistent use before you notice a significant improvement in your symptoms. For organ transplant patients, Imuran starts working more quickly to suppress the immune system and prevent rejection. Your doctor will monitor your progress to see how well the medication is working for you.
It is generally recommended to limit alcohol intake while taking Imuran (Azathioprine). Alcohol can increase the risk of liver problems, and Imuran itself can affect the liver. Combining them can put extra strain on your liver. You should discuss your alcohol use with your doctor to understand what is safe for you based on your overall health and liver function.
If you miss a dose of Imuran, you should take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Taking too much Imuran can increase your risk of serious side effects.
Imuran can cause fatigue or weakness as a side effect in some people. This may be a direct effect of the medication or related to its impact on your blood cells, potentially causing anemia. If you experience persistent or severe tiredness, you should speak with your doctor. They can determine the cause and suggest ways to manage this side effect.
Imuran may cause temporary hair thinning or hair loss in a small number of people. This side effect is usually mild and is more common at higher doses. The hair loss is typically not permanent, and your hair should return to normal if the dose is lowered or after you stop taking the medication. Discuss any concerns about hair loss with your healthcare provider.
There are no specific foods that you must avoid while taking Imuran (Azathioprine). A healthy, balanced diet is generally recommended. However, it is important to take Imuran with food or milk to help reduce potential stomach upset or nausea. Always follow your doctor's dietary advice, especially after an organ transplant, as you may have other specific dietary restrictions.
Long-term use of Imuran (Azathioprine) can slightly increase the risk of developing certain types of cancer, particularly skin cancer and lymphoma. This is because it suppresses the immune system. Your doctor will discuss this risk with you. It is important to protect your skin from the sun by using sunscreen and wearing protective clothing while taking this medication.
While taking Imuran, your doctor will require you to have regular blood tests. These tests are crucial for monitoring your blood cell counts (red cells, white cells, and platelets) and checking your liver function. These tests help ensure the medication is working safely and allow your doctor to adjust the dose if necessary to minimize the risk of serious side effects.
You should not receive "live" vaccines while taking Imuran because it weakens your immune system. Live vaccines contain a weakened form of a virus and could cause a serious infection in someone with a suppressed immune system. Inactivated (killed) vaccines, like the flu shot, are usually safe. Always consult your doctor before getting any type of vaccination while on Imuran treatment.
Imuran tablets should be stored at room temperature, away from direct light, heat, and moisture. Keep the medication in its original container with the lid tightly closed. It is also very important to keep Imuran and all other medications out of the reach of children and pets to prevent accidental ingestion. Do not store it in the bathroom where humidity is high.
Imuran is generally not recommended for use during pregnancy as it may harm an unborn baby. If you are pregnant or planning to become pregnant, you must discuss the risks and benefits with your doctor. Effective birth control is strongly advised for both men and women while taking Imuran and for a period after stopping treatment.
Imuran should not be taken by individuals who are allergic to azathioprine or who are pregnant. It is also contraindicated for patients with certain severe liver conditions or specific genetic mutations like TPMT deficiency, which affects how the body metabolizes the drug. Your doctor will review your medical history to ensure Imuran is a safe choice for you before prescribing it.
To be safe, pregnant women should avoid handling Imuran tablets. The active ingredient can potentially be absorbed through the skin. If you are pregnant and must handle the medication (for example, as a caregiver), it is recommended to wear gloves and wash your hands thoroughly afterward. This minimizes any potential risk of exposure to the developing baby.
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