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For visual reference only; actual product may vary
US Name:
Enbrel
Alternative Names:
Enbrel
Active Ingredients:
Etanercept
Brand Manufacturer:
Wyeth
Manufacturer Location:
Ireland
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Click here to view Product Insert
For visual reference only; actual product may vary
Enbrel (Etanercept) is an injectable biologic medication for treating autoimmune conditions. It is prescribed for rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. By blocking a protein causing inflammation, Enbrel effectively reduces joint pain and skin symptoms. This product requires cold shipping.
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Enbrel is an injectable biologic medication prescribed to treat several chronic autoimmune conditions. Its generic name is etanercept. It belongs to a class of drugs known as tumor necrosis factor (TNF) inhibitors. Enbrel is used for rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. It also treats plaque psoriasis and juvenile idiopathic arthritis. This medication helps manage long-term inflammatory diseases.
Enbrel works by targeting and blocking a specific protein in your immune system called tumor necrosis factor. In many autoimmune diseases, the body produces too much TNF. This excess TNF causes inflammation, leading to joint pain, stiffness, and skin lesions. By neutralizing TNF, Enbrel helps to interrupt this inflammatory process. This action reduces symptoms and can help prevent further tissue damage associated with these conditions.
Enbrel is intended for patients who have been diagnosed with certain inflammatory autoimmune disorders. It is often prescribed for adults with moderate to severe rheumatoid arthritis or psoriatic arthritis. It is also used for those with ankylosing spondylitis and chronic plaque psoriasis. Doctors may recommend Enbrel when other treatments have not provided enough relief. It is also approved for children with some forms of juvenile idiopathic arthritis.
Enbrel is administered as a subcutaneous injection, which means it is injected just under the skin. Your doctor will show you how to inject the medication correctly. For most adult conditions, the standard dose is 50 mg given once per week. For plaque psoriasis, a higher starting dose might be used for the first twelve weeks. The dosage for children is based on their body weight. Always rotate injection sites between the thigh, abdomen, and upper arm.
Enbrel can cause side effects, although many people experience only mild ones. The most common issues are reactions at the injection site. These include redness, pain, itching, or swelling. Some people might get upper respiratory infections, like a cold, or headaches. A more serious risk is an increased chance of getting infections. This is because Enbrel affects the immune system. You should report any new or worsening symptoms to your doctor right away. Seek immediate medical help for signs of a severe allergic reaction.
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Most people taking Enbrel have mild side effects. However, you should be aware of all potential reactions. Always read the patient leaflet included with your medicine.
Common side effects include:
Serious side effects are less common but require prompt medical attention. Enbrel can increase your risk of developing serious infections because it affects your immune system. Contact your doctor immediately if you develop a fever, persistent cough, or other signs of infection. In rare cases, severe allergic reactions can occur. Seek emergency care for facial swelling, difficulty breathing, or a severe rash.
Enbrel is used for several autoimmune and inflammatory conditions:
Enbrel is administered as an injection under the skin, a method known as subcutaneous injection. Patients or caregivers can be trained to give the injections at home. The most common injection sites are the front of the thighs, the abdomen, or the upper arms. It is important to rotate injection sites to avoid soreness or skin reactions.
Enbrel may start to improve symptoms within 2 to 4 weeks of starting treatment. However, it can take up to 3 to 6 months to experience the full benefits of the medication. The exact timeline varies between individuals and the condition being treated. Consistent use as prescribed is key to achieving the best results.
If you miss a dose of Enbrel, you should take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not inject a double dose to make up for the one you missed. Consult your pharmacist if you are unsure.
You can travel with Enbrel, but you must keep it at the correct temperature. It should be stored in a cooler with ice packs, but you must prevent the medication from freezing. Enbrel may be kept at room temperature for a single period of up to 14 days, after which time it must be used or discarded.
Enbrel should be stored in the refrigerator between 36°F and 46°F (2°C and 8°C). Keep it in its original carton to protect it from light and do not freeze it. If necessary, it can be kept at room temperature for up to 14 days. Once removed from the fridge, it cannot be put back.
Enbrel can lower your immune system's ability to fight infections, which increases your risk. You should tell your doctor about any signs of infection, such as fever, cough, or flu-like symptoms. Your doctor will likely test you for tuberculosis (TB) before starting treatment and will monitor you during therapy.
Patients taking Enbrel should not receive live vaccines, as they can cause serious infections. Inactivated vaccines, like the standard flu shot, are generally considered safe and are often recommended. It is important to discuss your vaccination plan with your doctor before you start your Enbrel treatment to ensure your safety.
The most common side effects of Enbrel are reactions at the injection site, such as redness, itching, pain, or swelling. Other frequent side effects may include upper respiratory infections and headaches. These symptoms are usually mild to moderate and may decrease over time as your body adjusts to the medication.
While rare, Enbrel can cause serious side effects. These include an increased risk of serious infections that may lead to hospitalization, neurological problems, new or worsening heart failure, and certain blood disorders. You should immediately contact your doctor if you experience any severe or unusual symptoms while taking this medication.
Moderate alcohol consumption is not known to have a major interaction with Enbrel. However, alcohol can have its own effects on your liver and may worsen symptoms of your underlying autoimmune condition. It is always best to discuss your alcohol use with your doctor to ensure it is safe for your situation.
Enbrel is not a steroid. It is a type of biologic drug called a tumor necrosis factor (TNF) inhibitor. Unlike steroids, which have broad anti-inflammatory effects, Enbrel specifically targets TNF. This protein plays a key role in the inflammation associated with various autoimmune diseases.
Enbrel can be kept at room temperature (up to 77°F or 25°C) for a single period of up to 14 days. After this time, if it has not been used, it must be discarded. Do not return Enbrel to the refrigerator once it has reached room temperature, as this can affect its stability and effectiveness.
Using Enbrel during pregnancy should only be done if it is clearly needed and after a thorough discussion with your doctor. The effects of etanercept on an unborn baby are not fully understood. Your healthcare provider will carefully weigh the potential benefits of the treatment against any potential risks to the fetus.
Weight gain is not listed as a common side effect of Enbrel in its clinical trials. However, some patients may experience changes in weight. This could be due to feeling better, having an increased appetite after symptoms improve, or other factors not directly related to the medicine itself. Discuss any significant weight changes with your doctor.
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