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For visual reference only; actual product may vary
US Name:
Dovato
Alternative Names:
Dovato
Active Ingredients:
Dolutegravir/Lamivudine
Brand Manufacturer:
GSK
Manufacturer Location:
Spain
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Click here to view Product Insert
For visual reference only; actual product may vary
Dovato is a complete prescription regimen used to treat HIV-1 infection in adults. This powerful once-daily tablet combines two antiretroviral drugs to effectively suppress the virus and help you manage your health. It is suitable for many patients starting or switching their HIV treatment.
| Dovato Brand | 50/300mg 30 Tablets |
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Our price: $1,180.00 |
Dovato is a prescription medication that combines two active ingredients, dolutegravir and lamivudine, into a single daily tablet. It is a complete antiretroviral regimen used for the treatment of Human Immunodeficiency Virus 1 (HIV-1) infection. HIV is a virus that attacks the body’s immune system. Dovato helps control the virus but is not a cure for HIV. It is designed for adults who are either starting HIV-1 treatment for the first time or are replacing their current HIV-1 medications.
Dovato works by using its two active ingredients to stop the HIV virus from replicating in the body. Dolutegravir is an integrase strand transfer inhibitor (INSTI). It blocks an enzyme called integrase, which the virus needs to insert its genetic material into human immune cells (CD4 cells). Lamivudine is a nucleoside analog reverse transcriptase inhibitor (NRTI). It blocks reverse transcriptase, another enzyme the virus uses to make copies of itself. By disrupting this process, Dovato effectively reduces the amount of HIV in the blood (the viral load).
Dovato is intended for adults and adolescents aged 12 and older who weigh at least 40 kg (88 lbs) with HIV-1 infection. It is prescribed for those who have not previously taken antiretroviral therapy. It can also be used to replace the current antiretroviral regimen for individuals who are virologically suppressed. This means their viral load is consistently low on a stable treatment plan. Your doctor will determine if Dovato is the right choice based on your medical history and current health status.
Dovato is typically prescribed as one tablet taken orally once each day. The tablet can be taken with or without food, offering flexibility for daily schedules. It is important to take Dovato at the same time every day to maintain stable levels of the medicine in your blood. Be sure to follow your doctor’s instructions precisely. Certain other medicines, like calcium or iron supplements and some antacids, can interfere with how Dovato is absorbed. It should be taken at least two hours before or six hours after these products.
Dovato may cause some side effects, although not everyone will experience them. The most common side effects are generally mild and can include headaches, diarrhea, nausea, and difficulty sleeping. Some people may also feel dizzy or tired. More serious side effects are rare but can happen. These include severe allergic reactions, liver problems, and worsening depression or mood changes. If you have a history of depression, watch for any new or worsening symptoms. Contact your healthcare provider immediately if you experience a skin rash, yellowing skin or eyes, or thoughts of self-harm.
IsraelPharm provides a reliable and affordable way to access your essential medications like Dovato. We are committed to making treatment more accessible by offering competitive pricing on brand-name drugs sourced from regulated international pharmacies. Our streamlined online ordering process is simple, secure, and convenient. A licensed pharmacist reviews every prescription to ensure accuracy and safety. With discreet packaging and direct shipping to your door, IsraelPharm is your trusted partner for managing your health effectively and affordably.
Most people taking Dovato do not experience serious side effects. However, like any medication, it has potential risks. Consult your doctor for a full list of side effects.
Common side effects may include:
Less common but serious side effects can include:
Seek immediate medical help if you experience signs of an allergic reaction, liver problems (dark urine, yellow skin), or thoughts of self-harm.
Dovato is a prescription medication indicated for the treatment of HIV-1 infection in adults and adolescents (12 years and older weighing at least 40kg) who are:
Yes, Dovato is a complete HIV-1 treatment regimen contained in a single daily tablet. It includes two different antiretroviral drugs, dolutegravir and lamivudine, that work together to suppress the virus. This means most patients do not need to take any other HIV medications along with Dovato.
Dovato works best when a consistent level is maintained in your body. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Do not take two doses at once to make up for a missed one.
Dovato does not cure HIV infection or AIDS. It is an antiretroviral therapy that suppresses the virus, reducing your viral load to undetectable levels. This helps your immune system recover and lowers the risk of transmitting HIV to others, but it must be taken daily for life to remain effective.
Dovato begins working soon after you start taking it to lower the amount of HIV in your blood. It can take several weeks to a few months for your viral load to become undetectable. Your doctor will monitor your blood work regularly to track your progress and ensure the medication is working effectively.
Dovato can have side effects like dizziness and, in rare cases, can affect the liver. Alcohol can worsen these effects and put extra strain on your liver. It is generally recommended to limit alcohol consumption while on this medication. Always discuss your alcohol use with your doctor for personalized advice.
Dovato has been associated with potential weight gain in some individuals. This effect can be linked to the dolutegravir component and is also a result of the body recovering from the HIV infection itself. Discuss any significant or concerning weight changes with your doctor so they can monitor your overall health.
Dovato should be stored at room temperature, ideally below 30°C (86°F), in its original container. Keep the medication in a dry place away from excess heat and moisture, such as a steamy bathroom. As with all prescription drugs, store it securely and out of the reach of children and pets.
Dovato may not be recommended for patients who have severe kidney problems. The dosage of lamivudine, one of the components, may need to be adjusted for kidney impairment, and Dovato is a fixed-dose tablet. Your doctor will evaluate your kidney function before prescribing it to ensure it is safe for you.
Dovato use is approached with caution during pregnancy, especially in the first trimester, due to potential risks. If you are pregnant or planning to become pregnant, you must have a thorough discussion with your doctor. They will help you weigh the risks and benefits to decide on the best treatment plan for you and your baby.
Dovato treatment can help you achieve an undetectable viral load. This clinical term means the amount of HIV-1 virus in your blood is so low that it cannot be measured by a standard lab test. Reaching and maintaining this status protects your immune system and virtually eliminates the risk of transmitting HIV through sex.
Yes, Dovato is approved for use in patients who are switching from their current stable antiretroviral therapy. To be eligible, your viral load must be suppressed (undetectable) and you must not have a history of treatment failure. Your doctor will determine if switching to Dovato is an appropriate option for you.
No, Dovato can be taken with or without food. This provides you with the flexibility to take it at a time that fits your daily routine. The most important thing is to take your dose at the same time each day to maintain consistent drug levels in your body for maximum effectiveness.
Yes, Dovato can interact with certain supplements and antacids. Products containing calcium, iron, or magnesium can bind to dolutegravir and reduce its absorption. To avoid this, you should take Dovato at least 2 hours before or 6 hours after taking any of these supplements or medications.
Suddenly stopping Dovato can have serious consequences for your health. The HIV viral load in your blood can increase very quickly, potentially weakening your immune system. For patients with Hepatitis B, stopping Dovato can cause a severe flare-up of the liver disease. Never stop taking Dovato without your doctor's guidance.
Dovato is not suitable for everyone. You should not take Dovato if you are taking a heart medication called dofetilide (Tikosyn), as it can cause a life-threatening interaction. It's also not for those with a history of a severe allergic reaction to its components, dolutegravir or lamivudine. Your doctor will review your health history.
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