Spend $99, get free U.S. shipping*
Tariff now required on U.S. shipments. Learn more »
Tel: 1-866-456-3768 Fax: 1-866-544-8993
For visual reference only; actual product may vary
For visual reference only; actual product may vary
Diacerein is a slow-acting medication used to relieve the symptoms of osteoarthritis, such as joint pain and inflammation. It works differently from typical NSAIDs by targeting specific inflammatory pathways, helping to protect cartilage over time. It is taken orally to manage long-term joint conditions.
| Diatrim Generic | 50mg 30 Caplets |
-
|
Our price: $31.00 |
 Inflammation Pack | 30 Pouches 1 Pouch a Day | –+ | Our price: $63.75 |
Diacerein is a slow-acting oral medication used to treat the symptoms of joint diseases like osteoarthritis, particularly of the hip and knee. Unlike common nonsteroidal anti-inflammatory drugs (NSAIDs), it is not intended for short-term pain relief but rather for long-term management of the condition. Its primary purpose is to reduce pain and inflammation while also slowing down the progression of cartilage degradation in the affected joints. Because it has a unique mechanism, it provides an alternative for patients who may not tolerate traditional pain relievers well.
Diacerein works by inhibiting the production and activity of a pro-inflammatory cytokine called interleukin-1β (IL-1β). This molecule plays a key role in the inflammation and cartilage destruction seen in osteoarthritis. By blocking IL-1β, Diacerein helps to reduce joint inflammation, decrease pain, and slow down the breakdown of cartilage. This mechanism is fundamentally different from NSAIDs, which primarily block prostaglandin synthesis. This targeted approach helps manage osteoarthritis symptoms while potentially preserving joint structure over the long term.
Diacerein is for adults diagnosed with osteoarthritis who need a long-term treatment to manage symptoms and slow disease progression. It is often considered a second-line therapy, making it a suitable option for patients who have not found sufficient relief with first-line treatments like acetaminophen or for those who cannot take NSAIDs due to gastrointestinal or cardiovascular risks. Because its effects build over time, it is intended for individuals seeking sustained management rather than immediate pain relief.
Diacerein is administered as an oral capsule that should always be taken with food to improve absorption and reduce the risk of gastrointestinal side effects. Treatment is often initiated with a lower dose, such as one 50mg capsule per day with the evening meal for the first two to four weeks. If well-tolerated, the dosage is typically increased to the standard 50mg twice daily. This gradual start helps the body adjust and minimizes the likelihood of diarrhea. Always follow your doctor’s specific instructions for dosage and duration of treatment.
The most common side effects of Diacerein are primarily gastrointestinal, including diarrhea, soft stools, and abdominal pain. These effects are most common in the first few weeks of treatment and often lessen as your body adapts. A very common and harmless side effect is a change in urine color to a dark yellow or red, which is normal. Though rare, serious side effects can occur, including liver problems. You should contact your doctor immediately if you experience symptoms like persistent abdominal pain, fatigue, yellowing of the skin or eyes, or unusually dark urine (distinct from the harmless color change).
IsraelPharm offers a reliable and affordable way to access your prescription medications like Diacerein without compromising on quality or safety. We source our products from legitimate, licensed pharmacies, ensuring you receive authentic medication. Our straightforward online ordering process and dedicated customer support team make managing your health convenient and hassle-free. By choosing IsraelPharm, you benefit from competitive pricing, allowing you to focus on your health without worrying about high costs. We ship directly to your door, providing a seamless link between you and your treatment.
Like all medications, Diacerein can cause side effects. It’s important to be aware of them and consult your doctor if you have concerns.
Contact your doctor immediately if you experience any signs of liver problems, such as:
Diacerein is used for the long-term treatment of degenerative joint diseases, such as:
Diacerein is a slow-acting medication, so its effects are not immediate. Patients typically begin to notice an improvement in pain and joint function after about two to four weeks of continuous use. The full therapeutic benefits are usually felt after four to six weeks. It is designed for long-term management rather than for providing rapid, short-term pain relief like traditional painkillers.
Yes, you should always take Diacerein with a meal or a substantial snack. Taking it with food helps to improve the drug's absorption into your bloodstream and, more importantly, can significantly reduce the risk of gastrointestinal side effects such as diarrhea and abdominal pain. It is often recommended to take the capsules with your morning and evening meals.
If you miss a dose of Diacerein, take it as soon as you remember. However, if it is almost time for your next scheduled dose, you should skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed, as this can increase your risk of side effects like diarrhea.
Diacerein can cause a distinct change in your urine color, making it appear as a dark yellow, orange, or even reddish color. This is a common and completely harmless side effect caused by the way the drug is metabolized and excreted from the body. It does not indicate any problem with your health or kidneys and is expected to resolve after you stop taking the medication.
Yes, diarrhea is the most frequently reported side effect of Diacerein, often occurring within the first few weeks of starting treatment. This is why doctors usually prescribe a lower dose for the first month to help your body adjust. The diarrhea is typically mild and temporary. However, if it becomes severe or persistent, you should contact your healthcare provider for advice.
You may be able to take simple analgesics like acetaminophen (Tylenol) alongside Diacerein, especially when you first start treatment and are waiting for its effects to build. However, you should be cautious with NSAIDs like ibuprofen (Advil). Always consult your doctor or pharmacist before combining Diacerein with any other pain medication to ensure it is safe for you and to avoid potential interactions.
No, Diacerein is neither a nonsteroidal anti-inflammatory drug (NSAID) nor a steroid. It belongs to a class of drugs called anthraquinones. Its mechanism is different, as it specifically targets interleukin-1, a key protein involved in the inflammation and cartilage damage of osteoarthritis. This makes it a unique treatment option for patients who may not be suitable candidates for NSAIDs.
While rare, Diacerein can affect the liver. You should contact your doctor immediately if you notice any signs of liver issues. These include yellowing of your skin or the whites of your eyes (jaundice), unusual and persistent tiredness, loss of appetite, severe abdominal pain, or a combination of dark urine and pale-colored stools. Regular monitoring may be recommended by your doctor.
You should store Diacerein capsules at room temperature, away from excess heat, direct sunlight, and moisture. Do not store them in the bathroom, as the humidity can degrade the medication. Keep the capsules in their original packaging and ensure they are stored safely out of the reach of children and pets to prevent accidental ingestion.
No, there is currently no cure for osteoarthritis. Diacerein is not a cure, but it is an effective long-term treatment for managing the condition. It helps to reduce symptoms like pain and inflammation and works to slow down the progressive damage to the cartilage in your joints. This can improve your overall quality of life and help maintain joint function for longer.
It is generally advisable to limit or avoid alcohol consumption while taking Diacerein. Both alcohol and Diacerein are processed by the liver. Consuming alcohol, especially in large amounts, could potentially increase the risk of liver-related side effects. Always check with your doctor for personalized advice regarding alcohol use with your medication based on your overall health status.
Caution is advised when Diacerein is prescribed to individuals over the age of 65, particularly when starting treatment. Older adults may be more susceptible to side effects like diarrhea, which can lead to dehydration and other complications. Your doctor will carefully weigh the benefits against the risks and may suggest close monitoring, especially during the initial phase of therapy.
Send Your Prescription
No Hidden Fees
Generally 7-10 Business Days
IsraelPharm has been delivering lost cost prescriptions from Israel for over 15 years worldwide. Daily flights allow us to get your medications dispatched fast! Delivery to the USA is under 10 days and you can track and trace every order.
Is your generic medication truly safe? Explore the hidden risks of global drug manufacturing and learn how sourcing brand-name medications can protect patient safety.
The symptoms of menopause, during which women can feel physical and emotional discomfort, are often blamed entirely on declining levels of estrogen, but the hormone imbalance behind the symptoms is more complicated. In the years
For most women going through menopause, vasomotor symptoms are not a footnote. Hot flashes and night sweats often interrupt sleep, derail meetings, and soak clothing. They persist on average seven to nine years, and in
