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Home / Online Pharmacy / Prolia

For visual reference only; actual product may vary

US Name:

Prolia
Alternative Names:

Prolia, Jubbonti
Active Ingredients:

Denosumab
Brand Manufacturer:

Brand
Manufacturer Location:

Netherlands
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Prolia ^*

For visual reference only; actual product may vary

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Prolia is prescribed to treat osteoporosis in people with prostate or breast cancer, bone loss that results from a reduction in testosterone, or systemic glucocorticoids therapy with prednisone.

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Prolia Brand	60mg 1 Pre-Filled Syringe	- Prolia – Brand, Prolia, 60mg, 1, Pre-Filled Syringe, 3486, Brand, 1251 + 0	Our price: $550.00
Jubbonti Generic	60mg 1 Pre-Filled Syringe	- Prolia – Generic, Jubbonti, 60mg, 1, Pre-Filled Syringe, 86057, Sandoz, 2834 + 0	Our price: $650.00

*Please note all prices are in US dollars

Description
Side Effects
Indications
FAQ
Video

Denosumab Brand (generic name: denosumab) is a human monoclonal antibody for the prevention of bone loss (osteoporosis) in postmenopausal women and in men who have a reduction in testosterone levels caused by surgery or treatment. It is also prescribed to prevent bone fractures in people with prostate or breast cancer who are undergoing treatment or with bone loss associated with long-term systemic glucocorticoid therapy with prednisone, where they are expected to remain on glucocorticoids for at least three months.

Caution

Women of childbearing age should use a barrier method of contraception while being treated with Denosumab Brand and for at least five months after stopping treatment. In case you become pregnant during treatment with Denosumab Brand or within five months after stopping treatment, please inform your doctor.

Dosage

Denosumab Brand is administered by professional healthcare providers. The recommended dosage is one dose administered once every six months as a single subcutaneous injection. Please follow the doctor’s instructions when ordering, and read the information in the manufacturer’s product leaflet that comes with the medication. Denosumab can carry serious health risks.

Storage

After receipt of the dose, it must be stored in the refrigerator at temperatures between 2°C/36°F and 8°C/47°F if it is not going to be administered within 30 days. Immediately before administration, it should be brought to room temperature (up to 25°C/77°F). As well, keep Denosumab Brand out of reach of babies and children. Please read our friendly tips on handling medicine safely

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Possible side effects of Denosumab include:

bone, joint, or muscle pain which can be severe
upper respiratory tract infection
constipation
back pain
muscle pain
pain in the arms and legs
anemia
diarrhea
hair loss (alopecia)
skin problems such as rash, itching, redness or eczema.

While taking Denosumab, there may be a greater likelihood of a severe infection, such as a skin, ear, stomach/gut, or bladder infection.

Inform a doctor immediately if there are signs of infection while taking the medication, such as:

fever/chills, night sweats
red/swollen/tender/warm skin
severe stomach or abdominal pain
ear pain or drainage, trouble hearing
frequent/painful/burning urination, or pink/bloody urine
severe itching, burning, rash, blistering, peeling, or dryness of the skin
cough or shortness of breath
pinpoint purple or red spots under your skin
flu symptoms
weight loss

Not all possible side effects can be listed here. If you experience any of these or other unexpected side effects, consult a healthcare provider immediately.

Denosumab Brand is a form of the generic drug denosumab that has been approved for the reduction of the risks of bone fractures in people with:

Postmenopausal osteoporosis
Osteoporosis in men treated with surgery or medication for prostate cancer with resulting androgen deprivation
Bone loss associated with long-term systemic glucocorticoid therapy
Bone loss in women with breast cancer due to aromatase inhibitor-induced estrogen depletion (low estrogen levels)

Postmenopausal women and men with reduced levels of testosterone have an increased risk of spinal, non-spinal, and hip fractures.

In clinical trials, Prolia was shown to help strengthen bone and increase bone mass. It also helped to reduce the incidence of vertebral, nonvertebral, and hip fractures in postmenopausal women with osteoporosis.
It may be suggested to avoid the use of Denosumab during pregnancy as denosumab may cause some harm to a fetus. Advising the prescribing doctor of the possibility of pregnancy during the course of treatment is very important. Denosumab Brand has been reported as causing a severe condition of the jaw bone known as osteonecrosis of the jaw (ONJ). If dental surgery or treatment is scheduled while receiving this medication, the responsible healthcare professional should be informed in advance that this medication is currently being used.
The prescribing healthcare professional must be made aware before starting this treatment if you are pregnant or planning to become pregnant. Use of denosumab is permitted only if the benefit to the mother outweighs the risk to the fetus. Otherwise, both men and women should avoid conception while taking denosumab. The use of barrier methods of contraception, such as condoms, is recommended.

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