Spend $99, get free U.S. shipping*

Tariff now required on U.S. shipments. Learn more »

Tel: 1-866-456-3768 Fax: 1-866-544-8993

For visual reference only; actual product may vary

  • US Name:

    Climara

  • Alternative Names:

    Climara, Climara Forte

  • Active Ingredients:

    Estradiol

  • Brand Manufacturer:

    Bayer

  • Manufacturer Location:

  • Click here to view Product Insert

  • Click here to view Product Insert

Climara *

For visual reference only; actual product may vary

Prescription Required
All third-party products, company names, and logos are trademarks™ or registered® trademarks are and remain the property of their respective holders. Their use does not imply any affiliation with or endorsement by them. All references on this site to third-party trademarks are intended to constitute nominative fair use under applicable trademark laws.

Climara (Estradiol) is a hormone replacement therapy patch used to manage symptoms of menopause. Applied once a week, it releases estrogen to relieve moderate-to-severe hot flashes, night sweats, and vaginal dryness. It can also help prevent postmenopausal osteoporosis.

Place your order

Climara Brand 50mcg
4 Patches
-
+
Our price:
$52.00
Climara Brand 25mcg
4 Patches
-
+
Our price:
$50.00
Climara Forte Brand 7.8mg
4 Patches
-
+
Our price:
$91.00

*Please note all prices are in US dollars

What is Climara?

Climara is a transdermal patch containing estradiol, a form of the hormone estrogen, used for hormone replacement therapy (HRT) to treat symptoms associated with menopause. Manufactured by Bayer, this prescription medication is designed to be applied to the skin once a week. This delivery system provides a continuous and stable release of estradiol into the bloodstream, effectively replacing the estrogen the body no longer produces in sufficient amounts after menopause.

How does Climara work?

Climara works by releasing estradiol directly through the skin into the bloodstream, replacing the estrogen that the ovaries stop producing during and after menopause. By restoring estrogen to pre-menopausal levels, Climara addresses the root cause of many uncomfortable symptoms. This hormonal stabilization helps regulate body temperature, reducing the frequency and severity of hot flashes and night sweats. It also helps maintain the thickness and elasticity of tissues in the vagina and urinary tract, alleviating dryness, itching, and urinary discomfort. The transdermal system allows the hormone to bypass the digestive system, leading to steady and sustained therapeutic levels.

Who is Climara for?

Climara is for postmenopausal women seeking relief from moderate to severe symptoms caused by estrogen deficiency. It is primarily prescribed to treat vasomotor symptoms, such as sudden hot flashes, night sweats, and resulting sleep disturbances. It is also effective for treating vulvar and vaginal atrophy, which can cause dryness, irritation, and pain during intercourse. Additionally, Climara can be used as a treatment for hypoestrogenism (low estrogen levels) resulting from conditions like hypogonadism or ovarian failure, and to help prevent post-menopausal osteoporosis in women at high risk who cannot use other non-estrogen medications.

Dosage and administration

Climara is a once-weekly patch that should be applied to a clean, dry, and hairless area of skin, typically on the lower abdomen or the upper part of the buttocks. Therapy is usually initiated at the lowest effective dose as determined by a doctor. The patch should never be applied to the breasts or to skin that is oily, damaged, or irritated. To ensure proper adhesion, press the patch firmly in place for about 10 seconds. It is essential to rotate the application site each week, with at least a one-week interval before using the same spot again. If a patch falls off, it may be reapplied or a new one can be used for the remainder of the 7-day dosing interval, maintaining the original patch change day.

Side effects

Most women use Climara without issues, but some may experience side effects, most commonly skin irritation, redness, or itching at the application site, as well as headaches or breast tenderness. Other potential common side effects include abdominal discomfort, mild nausea, fluid retention, and unexpected vaginal spotting or bleeding. While most side effects are mild, serious reactions can occur. Seek immediate medical attention if you experience sudden chest pain, shortness of breath, severe headaches, vision changes, signs of a blood clot like swelling or pain in one leg, or sudden heavy vaginal bleeding, as these may indicate a rare but dangerous condition.

Why buy from IsraelPharm?

IsraelPharm provides a reliable, convenient, and affordable way to purchase authentic, brand-name Climara patches online. We are committed to patient health and safety, sourcing all our medications from licensed manufacturers and distributors. Our streamlined ordering process and direct-to-consumer shipping model allow us to offer significant savings on your prescription medications. With a team of knowledgeable pharmacists and a focus on customer care, IsraelPharm is your trusted source for managing your health affordably.

Common side effects:

  • Skin irritation, itching, or redness at the patch site
  • Headache
  • Breast tenderness or pain
  • Abdominal discomfort or bloating
  • Mild nausea
  • Fluid retention (edema)
  • Vaginal spotting or bleeding

Serious side effects requiring immediate medical action:

  • Sudden chest pain or shortness of breath
  • Signs of a blood clot (swelling, warmth, or pain in one leg)
  • Severe headache or vision changes
  • Symptoms of a stroke (sudden numbness, confusion, trouble speaking)
  • Jaundice (yellowing of the skin or eyes)
  • A new breast lump
  • Sudden, heavy, or unusual vaginal bleeding

Vasomotor symptoms of menopause

  • Sudden hot flashes
  • Night sweats
  • Sleep disturbances
  • Mood changes

Vulvar and vaginal atrophy due to menopause

  • Vaginal dryness
  • Itching or irritation
  • Pain with intercourse
  • Urinary discomfort

Hypoestrogenism

For low estrogen from hypogonadism, castration, or primary ovarian failure.

Prevention of post-menopausal osteoporosis

Reduces bone loss in women at significant risk of fracture.

Getting started with IsraelPharm

Required

Send Your Prescription

Secure Payment

No Hidden Fees

Fast Shipping

Generally 7-10 Business Days

Fast delivery
Secure payment
Genuine brands
Pharmacist oversight
Proudly Israeli

Ordering is
simple and safe.

IsraelPharm has been delivering lost cost prescriptions from Israel for over 15 years worldwide. Daily flights allow us to get your medications dispatched fast! Delivery to the USA is under 10 days and you can track and trace every order.

Read more from our blog

reduce side effects of GLP-1

GLP-1 Risks Explained Simply

You’ve probably seen headlines questioning the safety of GLP-1 medicines – the cornerstone of the wave of the latest drugs that have revolutionized many areas of healthcare, primarily in control of type 2 diabetes and

Read More »

Login

Fast Delivery
Ships from Israel
Secure Payment
Genuine Brands
Pharmacist Oversight
Proudly Israeli
Free Shipping on orders over $99*

Having issues?

Daily from 9am-8pm EST.
IsraelPharm
Hataasia 16
Bet Shemesh Israel, 9906105

Sign up for $10 off your first order!

Enjoy exclusive deals we only share via email