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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Balversa (Erdafitinib) is a targeted prescription therapy for adults with locally advanced or metastatic urothelial carcinoma (bladder cancer) that has specific FGFR genetic alterations. It works by blocking cancer cell growth, helping to manage disease spread and improve outcomes for patients who qualify for this treatment.
| Balversa Brand | 4mg 56 Tablets |
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Our price: $18,093.00 |
Balversa (erdafitinib) is a prescription oral medication used to treat adults with locally advanced or metastatic bladder cancer, specifically a type called urothelial carcinoma, that has certain abnormal fibroblast growth factor receptor (FGFR) genes. Urothelial carcinoma is the most common type of bladder cancer, and in some individuals, its growth is fueled by these specific genetic mutations. Balversa is classified as a kinase inhibitor, a type of targeted therapy designed to attack cancer cells with precision while minimizing damage to healthy cells.
Balversa works by specifically targeting and blocking the activity of abnormal FGFR proteins, which are responsible for driving the growth and spread of cancer cells in some patients. In a healthy body, FGFRs help regulate cell growth and division. However, when these receptors have mutations, they can become overactive, sending constant signals for cancer cells to multiply and survive. By inhibiting these specific proteins, Balversa effectively cuts off the signal, which can slow or even stop tumor growth, and in some cases, shrink existing tumors.
Balversa is intended for adult patients diagnosed with locally advanced or metastatic urothelial carcinoma whose tumors have susceptible FGFR3 or FGFR2 genetic alterations. Before starting treatment, your doctor will require a test to confirm your tumor has the specific genetic marker that this drug targets. It is typically prescribed after the cancer has not responded to or has progressed after at least one round of platinum-containing chemotherapy. This medication may not be suitable for everyone. It should not be taken by women who are pregnant or breastfeeding, individuals with a known allergy to erdafitinib, or children.
Balversa is typically taken as a once-daily oral tablet, with or without food, exactly as prescribed by your healthcare provider. Your doctor will determine the correct dose for you, which is often started at 8mg daily and may be increased based on your response and blood phosphate levels. The tablet should be swallowed whole with water and not be crushed, split, or chewed. It is important to take your dose at the same time each day. If you miss a dose, take it as soon as you remember, but if it is close to your next scheduled dose, skip the missed one. Do not take two doses at once. Store Balversa at room temperature in its original container, away from moisture and direct light.
The most common side effects associated with Balversa include high phosphate levels in the blood, mouth sores, fatigue, and changes in kidney function, though more serious eye problems can also occur. Other frequent effects may include diarrhea, dry mouth, changes in your sense of taste, reduced appetite, and nail or skin problems. A serious but common side effect is central serous retinopathy, an eye disorder that can affect your vision. It is critical to contact your doctor immediately if you experience blurred vision, vision loss, or other visual changes during treatment. Your doctor will monitor you for these and other potential side effects.
IsraelPharm offers a secure and affordable way to purchase Balversa online, providing access to genuine medication from a trusted source with international pharmacy expertise. We are committed to making important medications accessible at competitive prices, bridging the gap between high costs and patient needs. When you order from us, you receive authentic Balversa manufactured by Jansen Cilag, delivered discreetly to your door. Our professional team is available to answer your questions and assist you throughout the ordering process, ensuring a safe and satisfactory experience.
The most common side effects of Balversa include:
Balversa can also cause serious eye problems, such as central serous retinopathy, which can lead to vision changes or loss. Tell your doctor immediately if you experience blurred vision or other visual changes. For a full list of effects, consult the patient information leaflet.
Balversa is indicated for the treatment of adult patients with:
Balversa is a targeted therapy for a type of bladder cancer called urothelial carcinoma. It's specifically for adult patients whose cancer is locally advanced or has spread (metastasized) and has a certain abnormality in the fibroblast growth factor receptor (FGFR) genes. Your doctor must test for this specific genetic marker to see if Balversa is right for you.
Your oncologist will order a special test on a sample of your tumor tissue. This is called a biomarker test or companion diagnostic test. It looks for specific genetic mutations, in this case, alterations in the FGFR2 or FGFR3 genes. The results of this test will confirm whether you are eligible for treatment with Balversa.
No, Balversa is not a traditional chemotherapy. It is a 'targeted therapy.' While chemotherapy works by attacking all rapidly dividing cells (both cancerous and healthy), Balversa specifically targets and blocks the FGFR proteins that cause your particular cancer to grow. This approach can lead to different and sometimes fewer side effects than traditional chemotherapy.
If you miss a dose, take it as soon as you remember on the same day. However, if it's already close to the time for your next scheduled dose, just skip the missed one and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one, as this can increase your risk of side effects.
Yes, Balversa can cause serious eye problems, including a condition called central serous retinopathy, where fluid builds up under the retina. Symptoms can include blurred vision, distorted vision, or seeing dark spots. Your doctor will schedule regular eye exams, but you should report any changes in your vision to them immediately.
Balversa can cause high phosphate levels in your blood (hyperphosphatemia). Your doctor will monitor this with blood tests. If your levels become too high, your doctor may recommend a diet low in phosphate. This involves limiting foods like dairy, red meat, and processed foods. They may also prescribe a phosphate-lowering therapy if needed.
You should store Balversa in its original container at room temperature, between 68°F to 77°F (20°C to 25°C). Keep the bottle tightly closed and in a dry place, away from moisture and direct sunlight. It is also very important to keep this medication out of the reach of children and pets.
No, you should avoid grapefruit and grapefruit juice during your treatment with Balversa. Grapefruit can interfere with how your body processes the medication, leading to higher levels of the drug in your bloodstream. This can significantly increase your risk of developing serious side effects. Always check with your doctor about potential food and drug interactions.
The time it takes for Balversa to show an effect varies from person to person. Some patients may see a response within a few weeks, while for others it might take a couple of months. Your oncologist will monitor your progress regularly using imaging scans, like CT or MRI, to see how the cancer is responding to the treatment.
The most common symptom of urothelial carcinoma is blood in the urine (hematuria), which might make urine look pink, red, or brown. Other symptoms can include frequent urination, a feeling of urgency to urinate, and pain or a burning sensation during urination. More advanced disease may cause lower back pain, fatigue, or unexplained weight loss.
No, you should not stop taking Balversa or change your dose unless your doctor tells you to. Even if you start to feel better and your symptoms improve, it is important to continue the treatment as prescribed. Stopping the medication early could allow the cancer cells to start growing again. Always consult your healthcare provider first.
Hyperphosphatemia is a medical term for having an abnormally high level of phosphate in your blood. It is a common side effect of Balversa because the drug affects how the kidneys handle phosphate. Your doctor will monitor your blood levels regularly. If they are too high, they may suggest a low-phosphate diet or start you on another medication to control it.
It is crucial to tell your doctor about all medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Some drugs can interact with Balversa, affecting how it works or increasing your risk of side effects. Your doctor will review your medication list to prevent any harmful interactions before you start treatment.
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