What is Adempas?
Adempas (Riociguat) is a prescription oral medication used to treat adults with two specific types of high blood pressure affecting the lungs, a condition broadly known as pulmonary hypertension. It is prescribed for patients with pulmonary arterial hypertension (PAH) to improve their ability to exercise and slow the worsening of the condition. It is also approved for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who cannot undergo surgery or have persistent high blood pressure after surgery.
How does Adempas work?
Adempas works by stimulating an enzyme in the body called soluble guanylate cyclase (sGC). This enzyme is part of a pathway that helps relax and widen blood vessels. By directly stimulating sGC and making it more sensitive to the body’s natural nitric oxide, Adempas helps to relax the pulmonary arteries. This action decreases the high pressure in the lungs, making it easier for the heart to pump blood, which improves exercise capacity and reduces symptoms.
Who is Adempas for?
Adempas is for adults who have been diagnosed with certain forms of pulmonary hypertension. This includes individuals with Group 1 pulmonary arterial hypertension (PAH), a condition where the lung’s arteries tighten and narrow. It is also prescribed for patients with Group 4 pulmonary hypertension, known as CTEPH, which is caused by old blood clots. For CTEPH, Adempas is an option for those who are considered inoperable or have persistent or recurrent symptoms after undergoing surgical treatment.
Dosage and administration
The correct dosage of Adempas is determined by your doctor and is often tailored to your specific needs and tolerance. Treatment usually begins with a low dose, which is gradually increased to the most effective and tolerable level. Adempas is typically taken three times a day, with or without food, and doses should be spaced about 6 to 8 hours apart. It is crucial to take your medication consistently as prescribed. If you smoke or quit smoking, inform your doctor, as this can affect how the drug works and may require a dose adjustment.
Side effects
Adempas can cause side effects, which may be mild or serious. Common mild side effects include headache, dizziness, indigestion, nausea, diarrhea, and swelling in the hands or feet. More serious side effects can occur, such as very low blood pressure (hypotension), an increased risk of bleeding, and potential harm to a developing fetus, which is why it is contraindicated in pregnancy. If you experience lightheadedness, chest pain, or cough up blood, contact your doctor immediately. This medication is not suitable for patients with Pulmonary Veno-Occlusive Disease (PVOD).
Why buy from IsraelPharm?
Buying from IsraelPharm provides a convenient, reliable, and affordable way to access your Adempas prescription. We are committed to providing authentic, brand-name medications sourced from trusted manufacturers like Bayer. Our streamlined online ordering process and dedicated customer support team ensure you can manage your treatment with confidence and ease. By choosing IsraelPharm, you benefit from competitive pricing on essential medications, helping to reduce the financial burden of managing chronic conditions like pulmonary hypertension, with delivery right to your door.
Adempas can cause side effects, which range from mild to severe. You should discuss these potential effects with your doctor.
The most common side effects include:
- Headache
- Dizziness
- Indigestion or heartburn
- Swelling of hands, legs, feet, or ankles (peripheral edema)
- Nausea, diarrhea, or vomiting
Serious side effects require immediate medical attention:
- Severe Birth Defects: Adempas must not be taken during pregnancy. Females must participate in the Adempas REMS program.
- Low Blood Pressure (Hypotension): May cause dizziness or lightheadedness, especially if you are dehydrated.
- Bleeding: Increased risk of bleeding, including coughing up blood.
- Worsening of PVOD: May cause fluid in the lungs (pulmonary edema) in patients with Pulmonary Veno-Occlusive Disease.
Adempas (Riociguat) is prescribed for adults diagnosed with specific types of high blood pressure in the arteries of the lungs. It is used to treat:
- Pulmonary Arterial Hypertension (PAH): To improve exercise ability, help slow the worsening of physical condition, and reduce symptoms.
- Chronic Thromboembolic Pulmonary Hypertension (CTEPH): For patients who cannot be treated with surgery or for whom high blood pressure in the lungs persists or returns after surgery.