For visual reference only; actual product may vary
For visual reference only; actual product may vary
Actemra (tocilizumab) is a prescription injectable medication used to treat inflammatory conditions like Rheumatoid Arthritis (RA), Giant Cell Arteritis (GCA), and specific types of Juvenile Idiopathic Arthritis. It works by targeting a source of inflammation to reduce symptoms and slow joint damage. An additional fee applies for cold chain shipping.
| Actemra Brand | 162mg 4 Pre-Filled Syringe |
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Actemra is an injectable prescription medicine, with the active ingredient tocilizumab, used to treat several inflammatory autoimmune conditions. It is classified as an interleukin-6 (IL-6) receptor antagonist, which means it works by targeting a specific part of the immune system to reduce inflammation. Actemra is primarily prescribed for adults with moderate to severe rheumatoid arthritis (RA) or giant cell arteritis (GCA), and for children with systemic or polyarticular juvenile idiopathic arthritis (sJIA or pJIA).
Actemra works by selectively blocking the inflammatory protein Interleukin-6 (IL-6) from binding to its receptors in your body. In autoimmune conditions like rheumatoid arthritis, the immune system produces too much IL-6, which leads to inflammation, joint pain, swelling, and damage. By preventing IL-6 from sending its inflammatory signals, Actemra helps to calm the overactive immune response, reduce symptoms, and slow the progression of the disease.
Actemra is intended for patients diagnosed with specific inflammatory autoimmune diseases who may not have had success with other treatments. This includes adults with moderate to severe rheumatoid arthritis, especially after other Disease-Modifying Antirheumatic Drugs (DMARDs) were not effective. It is also for adults with Giant Cell Arteritis (GCA). For younger patients, Actemra is approved for children aged one and older with active systemic juvenile idiopathic arthritis (sJIA) and children aged two and older with polyarticular juvenile idiopathic arthritis (pJIA).
Actemra is administered as a subcutaneous injection, meaning it is injected just under the skin. After initial training from a healthcare professional, most patients or their caregivers can administer the injections at home. The dosing schedule depends on the condition being treated and is typically once every one to two weeks. It is very important to rotate the injection site (e.g., abdomen, thigh) with each dose to prevent skin irritation. If you miss a dose, inject it as soon as you remember and then continue with your regular schedule.
Actemra may cause side effects, though many people experience none or only minor issues. The most common side effects include upper respiratory tract infections (like a cold or sinus infection), headache, increased blood pressure, and reactions at the injection site such as redness or pain. More serious side effects can occur, including an increased risk of serious infections, potential changes in liver enzyme levels or blood counts, and, rarely, severe allergic reactions. If you experience symptoms like a high fever, severe rash, or difficulty breathing, seek medical attention immediately.
Choosing IsraelPharm for your Actemra prescription provides a reliable and cost-effective way to manage your condition. We source our medications from authentic, licensed manufacturers like Hoffman La Roche, ensuring you receive the same high-quality treatment you would from a local pharmacy. Our streamlined online ordering process, dedicated customer support, and direct shipping make accessing your essential medication both simple and affordable, helping you focus more on your health and well-being.
Most individuals using Actemra do not have serious side effects, but some may occur. Seek immediate medical attention or call 911 if you experience signs of a severe allergic reaction, such as facial swelling, difficulty breathing, or a severe skin rash.
Common or possible side effects include:
This is not a complete list. If you experience these or any other unusual symptoms that persist or worry you, contact your healthcare provider for advice.
Actemra is prescribed to treat several inflammatory diseases where the immune system attacks the body’s own tissues. These include:
Actemra is given as a subcutaneous injection, which is an injection under the skin. A healthcare provider will teach you or a caregiver how to properly prepare and inject the medication using either a prefilled syringe or an autoinjector pen. It's important to rotate injection sites on your body, such as the abdomen and thighs, to avoid skin irritation. The frequency of injections depends on your prescribed treatment plan.
If you miss your scheduled dose of Actemra, you should inject the missed dose as soon as you realize it. Afterward, you can continue with your regular dosing schedule. However, if it is almost time for your next scheduled dose, it is best to skip the missed one and continue as normal. Never take a double dose to make up for a missed one.
The time it takes to feel the effects of Actemra can vary from person to person. Some patients may begin to notice an improvement in their symptoms, such as reduced joint pain and swelling, within a few weeks of starting treatment. For others, it may take a few months to experience the full benefits. Consistent use according to your doctor's prescription is key to achieving the best results.
Actemra must be stored in a refrigerator at a temperature between 36°F and 46°F (2°C to 8°C). Do not freeze the medication. Keep the prefilled syringe or autoinjector in its original carton to protect it from light until you are ready to use it. Do not use Actemra if it has been frozen or left at room temperature for an extended period.
You should discuss vaccinations with your doctor before starting Actemra. Generally, patients taking Actemra should not receive live vaccines. This is because Actemra affects your immune system, which could increase the risk of infection from a live virus or bacteria. Inactivated vaccines, like the flu shot, are typically considered safe, but always confirm with your healthcare provider first.
Yes, Actemra works by suppressing a part of your immune system to reduce inflammation. This action can lower your body's ability to fight off infections. While taking Actemra, you may be more susceptible to illnesses, from common colds to more serious infections. Your doctor will monitor you for any signs of infection during your treatment.
The most frequently reported side effects of Actemra include upper respiratory tract infections (like colds), headaches, increased blood pressure (hypertension), and injection site reactions such as redness, pain, or swelling. While many side effects are mild, it is important to report any persistent or bothersome symptoms to your doctor.
Yes, your doctor will likely order regular blood tests before you start and during your treatment with Actemra. These tests are important for monitoring your liver function (liver enzymes) and your blood cell counts (neutrophils and platelets), as Actemra can sometimes cause changes in these levels. This monitoring helps ensure the medication is safe for you to continue using.
You should consult your doctor about alcohol consumption while taking Actemra. Both alcohol and Actemra can affect the liver. Your doctor will monitor your liver function with blood tests, and drinking alcohol could potentially increase the risk of liver problems. Your healthcare provider can give you personalized advice based on your health and treatment plan.
Actemra and Methotrexate both treat conditions like rheumatoid arthritis, but they work differently. Methotrexate is a general immune suppressant. Actemra is a biologic drug that is more targeted; it specifically blocks an inflammatory protein called IL-6. Because of this different mechanism, Actemra is often used when a patient has not responded well enough to a traditional DMARD like Methotrexate.
Yes, an increase in blood pressure is a possible side effect of treatment with Actemra. Your healthcare provider should monitor your blood pressure regularly while you are taking this medication. If you have a history of hypertension or develop high blood pressure during treatment, your doctor may need to prescribe medication to manage it.
An injection site reaction is a common and usually mild side effect that can occur after injecting Actemra. Symptoms appear at the spot where the needle entered the skin and may include redness, itching, swelling, or pain. These reactions typically go away on their own within a few days. Rotating your injection sites can help reduce the likelihood of them occurring.
The use of Actemra during pregnancy has not been extensively studied, so its effects on an unborn baby are not fully known. It is crucial for women to use effective contraception while being treated with Actemra and for up to three months after stopping. If you are pregnant or planning to become pregnant, you must discuss the potential risks and benefits with your doctor.
No, Actemra (tocilizumab) is not a steroid. It is a biologic medication known as an interleukin-6 (IL-6) receptor antagonist. While steroids also reduce inflammation, they do so through a much broader mechanism. Actemra works by specifically targeting the IL-6 protein, which plays a key role in the inflammation associated with certain autoimmune diseases. It may be prescribed alongside steroids in some cases.
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