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For visual reference only; actual product may vary
US Name:
Actigall
Alternative Names:
Ursolit
Active Ingredients:
Ursodeoxycholic Acid
Brand Manufacturer:
Manufacturer Location:
Israel
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For visual reference only; actual product may vary
Actigall, with the active ingredient Ursodeoxycholic Acid, is a medication used to dissolve cholesterol gallstones in patients who may not be candidates for surgery. It also helps manage various chronic liver diseases by improving bile flow and reducing liver inflammation.
| Ursofalk Brand | 250mg 100 Capsules |
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Our price: $105.00 |
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| Ursolit Generic | 300mg 30 Capsules |
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Our price: $63.00 |
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| Ursofalk Brand | 500mg 100 Tablets |
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Our price: $259.00 |
Actigall is a prescription medication whose active ingredient, ursodeoxycholic acid, is a naturally occurring bile acid. It is primarily used to treat specific gallbladder and liver conditions. For the gallbladder, Actigall helps dissolve gallstones made of cholesterol, offering a non-surgical option for patients. For the liver, it is used to manage chronic diseases like primary biliary cirrhosis (PBC) by improving the flow of bile and protecting liver cells from damage.
Actigall works by reducing the amount of cholesterol produced by the liver and decreasing its absorption in the intestines. This change in the composition of bile makes it less likely to form stones and helps to gradually dissolve existing cholesterol-based gallstones. In chronic liver diseases, ursodeoxycholic acid protects liver cells from being damaged by toxic bile acids, improves liver function, and reduces inflammation by facilitating better bile flow out of the liver.
Actigall is primarily for patients with small, non-calcified (radiolucent) cholesterol gallstones who have a functioning gallbladder but are not good candidates for gallbladder surgery (cholecystectomy). It is also prescribed for individuals diagnosed with chronic cholestatic liver diseases. This includes conditions such as Primary Biliary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), and liver complications associated with cystic fibrosis. Doctors may also prescribe it to prevent gallstone formation in overweight patients undergoing rapid weight loss.
The correct dosage of Actigall is determined by a healthcare professional based on the specific condition being treated, the patient’s body weight, and their overall health profile. Actigall is an oral medication that comes in capsule form and is typically taken two to three times a day, often with meals to enhance absorption and reduce potential stomach upset. For treatment to be effective, the medication must be taken consistently as prescribed, often over a period of months or even years, especially for dissolving gallstones.
Like all medications, Actigall may cause side effects, though not everyone experiences them and they are often manageable. The most frequently reported side effect is diarrhea or pasty stools. Less common side effects can include nausea, vomiting, or upper abdominal pain. In rare cases, patients might experience skin reactions like itching or hives, or see calcification of their gallstones, which could make the medication less effective. It is important to discuss any persistent or bothersome side effects with your doctor.
Choosing IsraelPharm for your Actigall prescription ensures you receive genuine, high-quality medication at a competitive price. We source our products from reputable manufacturers and licensed distributors, giving you peace of mind about safety and efficacy. Our convenient online platform allows you to securely order your medication from the comfort of your home and have it delivered directly to you in the US, combining affordability with world-class service and a commitment to your health and well-being.
The most common side effects associated with Actigall may include:
Other, less common side effects that have been reported are:
You should consult your doctor or another healthcare provider if you experience any persistent or concerning side effects while taking this medication.
Actigall (Ursodeoxycholic Acid) is indicated for the treatment of several conditions, including:
The time it takes for Actigall to dissolve gallstones varies depending on the stone's size and composition. Treatment typically lasts from 3 to 24 months. Smaller stones may dissolve more quickly. Your doctor will likely perform ultrasounds every 6 months to monitor progress. Consistent, long-term use is crucial for the medication to be effective, and not all stones will dissolve completely.
Actigall is primarily used to dissolve gallstones located within the gallbladder. If your gallbladder has been surgically removed (a cholecystectomy), this specific use is no longer applicable. However, a doctor might still prescribe Actigall (ursodeoxycholic acid) for certain liver conditions, such as Primary Biliary Cirrhosis, even after gallbladder removal. Always consult your physician for guidance.
If you miss a dose of Actigall, take it as soon as you remember. However, if it is almost time for your next scheduled dose, you should skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed, as this can increase your risk of side effects.
Yes, it is generally recommended to take Actigall with food or a meal. Taking it with food can help increase the medication's absorption into your bloodstream, making it more effective. It may also help reduce the risk of potential gastrointestinal side effects like an upset stomach. Follow the specific instructions provided by your doctor or pharmacist.
Weight gain is not a commonly reported side effect of Actigall (ursodeoxycholic acid). The medication works by altering cholesterol metabolism and bile acid composition, which does not typically influence body weight. In fact, it is sometimes used to prevent gallstones in patients who are undergoing rapid weight loss. If you experience unexpected weight changes, discuss them with your doctor.
Yes, some medications can interfere with Actigall's effectiveness. These include antacids containing aluminum, cholesterol-lowering drugs like cholestyramine or colestipol (bile acid sequestrants), and estrogens or oral contraceptives. These substances can bind to Actigall or increase cholesterol secretion, counteracting its effects. Always inform your doctor of all medications and supplements you are taking.
You should discuss alcohol consumption with your doctor. Since Actigall is often prescribed for liver conditions, and alcohol can also damage the liver, it is generally wise to limit or avoid alcohol. Depending on the severity of your liver disease, your doctor may advise you to abstain completely to prevent further harm and allow the medication to work effectively.
Yes, they are related. Actigall is a brand name for the drug, while ursodiol is the shortened common name for its active ingredient, ursodeoxycholic acid. So, when you are taking Actigall, you are taking a specific brand of ursodeoxycholic acid. Generic versions are also available under the name Ursodiol. They are therapeutically equivalent but may have different inactive ingredients.
Actigall can indirectly help with discomfort associated with certain liver conditions. By improving bile flow and reducing inflammation and cell damage in the liver, it can alleviate some of the underlying causes of liver pain or discomfort in patients with diseases like PBC or PSC. However, it is not a direct pain reliever. Relief is a result of treating the disease process itself.
Actigall should be stored at room temperature, typically between 68-77°F (20-25°C), away from excess heat, moisture, and direct sunlight. Keep the bottle tightly sealed and out of the reach of children and pets. Do not store it in the bathroom, as the humidity can affect the medication. Discard any expired or unused medication as instructed by your pharmacist.
Actigall (ursodeoxycholic acid) is unique because it is a bile acid that works by dissolving cholesterol-based gallstones. Most other treatments for gallstones are surgical in nature, such as cholecystectomy (gallbladder removal). Actigall provides a non-invasive medical alternative for specific patients, primarily those with small, non-calcified stones who cannot or do not wish to undergo surgery.
Yes, Actigall can be used for prevention in certain situations. It is sometimes prescribed for obese patients who are undergoing rapid weight loss, as this process puts them at a higher risk of developing gallstones. By reducing cholesterol saturation in the bile during this period, Actigall can significantly lower the chances of gallstones forming.
While there isn't a mandatory special diet, your doctor may recommend dietary changes to support your treatment. A diet low in fat, cholesterol, and refined carbohydrates can help reduce the liver's cholesterol output, complementing Actigall's action and potentially speeding up gallstone dissolution. A balanced diet also supports overall liver and digestive health. Always follow your doctor's specific dietary advice.
The goal of Actigall treatment is to avoid surgery by dissolving gallstones. If the medication successfully dissolves the stones, surgery may not be necessary. However, treatment is not always successful, and gallstones can recur after stopping the medication. If Actigall is ineffective, or if you have complications like severe pain or inflammation, your doctor may then recommend gallbladder surgery (cholecystectomy).
Your doctor will monitor your progress with periodic check-ups and imaging tests. For gallstone treatment, this typically involves gallbladder ultrasounds every 6 months to see if the stones are shrinking. For liver conditions, your doctor will order regular blood tests to check your liver function enzymes. These tests help determine if the medication is working effectively and allow for dosage adjustments if needed.
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