If one or more of the following severe side effects are experienced, contact a doctor immediately:

• Allergic reaction that may appear as a rash, trouble with breathing, or swelling of the face, mouth, tongue, or neck
• Severe rectal or stomach pain
• Severe constipation or bloating
• Severe nausea and vomiting
• Bloody, black, or tarry stools, vomiting or coughing up blood

Other side effects are listed below and should be reported to a doctor or healthcare provider if experienced:

• Muscle cramp fits and jitteriness
• Change in heart rate, exhaustion, muscle weakness, and confusion
• High blood pressure, swelling of limbs, or problems with heart or kidneys
• Stomach, abdominal, or gut pain
• Loss of appetite
• Nausea 
• Diarrhea or constipation
• Coughing or shortness of breath 

Consult a doctor or healthcare provider before using this medication. If any other side effects are experienced, report them to a doctor for further instruction.

Before using this or any other medication, refer to the manufacturer’s product insert that comes with this medication.

Kayexalate powder is indicated for treating high levels of potassium in the blood (hyperkalemia). This condition may be common in patients with renal failure, patients with other medical conditions or patients taking certain medications. 

Kayexalate powder contains a resin that releases sodium ions and binds to potassium ions when it passes through the gastrointestinal tract. This medicine is not absorbed by the body.