For visual reference only; actual product may vary
For visual reference only; actual product may vary
Axera is a potent moisturizing cream with a high concentration of urea, designed to treat very dry, rough, and cracked skin. It is highly effective for managing skin conditions like eczema and psoriasis by restoring moisture and breaking down hard, thickened skin, promoting healing and providing significant relief.
| Axera Generic | Cream 1 Cream |
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Our price: $46.00 |
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Axera is a medicated topical cream whose active ingredient is urea, a compound naturally found in healthy skin. It is specifically formulated to treat a variety of skin conditions characterized by dryness, roughness, and scaling, such as eczema, psoriasis, and ichthyosis. Unlike cosmetic moisturizers, Axera works as both a powerful hydrating agent (humectant) and a keratolytic, meaning it helps break down the thick, outer layer of the skin to restore a smoother, healthier texture. The high concentration of urea allows it to penetrate deeply, providing moisture and relief where it’s needed most.
Axera works through the dual action of its active ingredient, urea. First, as a humectant, urea attracts and binds water from the deeper layers of the skin and the environment, pulling it into the dry, damaged cells of the epidermis (the outermost skin layer). This significantly increases the skin’s moisture content. Second, as a keratolytic agent, urea helps break down keratin, a hard protein that makes up the outer layer of the skin. In conditions like psoriasis or chronic eczema, skin cells can build up too quickly, creating thick, scaly patches. Axera softens and dissolves this excess keratin, helping the skin to shed these rough layers and become smoother.
Axera is for adults and, in some cases, children who are dealing with hyperkeratotic skin conditions—disorders that involve a thickening of the outer layer of the skin. This includes individuals diagnosed with chronic conditions like psoriasis, where scaly plaques form, or severe eczema with significant dryness and lichenification (thickened, leathery skin). It is also highly effective for treating xerosis (abnormally dry skin), ichthyosis (a genetic condition causing fish-like scaling), and for softening corns and calluses on the feet and hands. It is intended for those who have not found relief from standard over-the-counter moisturizers.
Axera should be applied topically to the affected skin as directed by your doctor or pharmacist. Generally, a thin layer of the cream is applied to the clean, dry, and intact affected areas one to two times daily. Gently rub the cream into the skin until it is fully absorbed. It is important not to apply Axera to broken, infected, or severely inflamed skin, as this can cause significant stinging and irritation. Avoid contact with eyes, lips, and other mucous membranes. Always wash your hands thoroughly after application to prevent spreading the cream to sensitive areas.
The most common side effects of Axera are typically mild and occur at the site of application. Some users may experience a temporary sensation of burning, stinging, itching, or redness, particularly if the cream is applied to cracked or sensitive skin. These feelings usually subside as your skin gets used to the treatment. In rare cases, a more serious allergic reaction could occur, with symptoms like a severe rash, hives, or swelling. If you experience persistent irritation or signs of an allergic reaction, stop using the product and consult your healthcare provider immediately. Most people who use Axera experience its benefits with minimal to no side effects.
IsraelPharm offers a trustworthy and cost-effective solution for purchasing Axera cream online. We source our medications from licensed pharmacies, ensuring you receive genuine, high-quality products that meet stringent health standards. Our platform provides an easy and secure way to manage your skincare needs from the comfort of your home. With competitive pricing and dedicated customer support, we bridge the gap between affordable medication and excellent service, making it simpler for you to access the treatments you need to maintain healthy skin without the high costs often found elsewhere.
Most side effects are mild and localized to the application area. Consult a doctor if they persist.
Axera is indicated for the treatment of dry, rough, and scaly skin conditions, including:
Axera is different due to its high concentration of urea, its active ingredient. While regular moisturizers primarily provide a surface barrier to prevent water loss, Axera actively draws moisture into the skin (humectant) and breaks down the hard, dead layer of skin cells (keratolytic). This dual action makes it a medicated treatment for conditions involving thickened, scaly skin, offering deeper and more effective hydration and smoothing than cosmetic lotions.
You may start to feel an improvement in your skin's softness and moisture levels within a few days of consistent use. However, for more chronic and severe conditions like psoriasis or thick calluses, it can take several weeks to see significant visible improvement. For best results, it is important to apply the cream as directed by your healthcare provider and to use it consistently every day.
Using Axera on the face is generally not recommended unless specifically advised by a dermatologist. Facial skin is much more sensitive than the skin on the body, and the high concentration of urea in Axera can cause significant irritation, redness, or a burning sensation. Always avoid the eye and mouth area. If you need a urea-based product for your face, ask your doctor about lower-concentration formulations made for sensitive facial skin.
There is limited data on the use of high-concentration urea cream during pregnancy. Since it is applied topically, very little of the active ingredient is absorbed into the bloodstream. However, it is always best to err on the side of caution. You should consult your healthcare provider or obstetrician before using Axera if you are pregnant, planning to become pregnant, or breastfeeding to ensure it is safe for you and your baby.
If you miss a dose of Axera, simply apply it as soon as you remember. However, if it is almost time for your next scheduled application, just skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for the one you missed. Applying extra cream will not improve results faster and may increase your risk of side effects like skin irritation.
It is best to ask your doctor or pharmacist before using other topical products on the same area you are treating with Axera. Applying other creams, lotions, or medications at the same time could either reduce Axera's effectiveness or increase the risk of irritation. If you need to use another product, your provider may recommend applying it at a different time of day.
Urea-based creams like Axera can sometimes have a faint odor that some people describe as being similar to ammonia. This is a normal characteristic of the active ingredient itself. Most formulations are designed to be as neutral as possible, and any slight scent usually dissipates quickly after the cream is absorbed into the skin. It is generally not considered to be a strong or unpleasant smell by most users.
You should store Axera cream at room temperature, away from direct heat, moisture, and sunlight. Keep the tube tightly sealed when you are not using it. Do not store it in the bathroom, where humidity can affect the cream’s consistency and effectiveness. As with all medications, it is crucial to keep Axera out of the reach of children and pets to prevent accidental ingestion.
No, Axera will not cause skin thinning (atrophy) in the way that topical steroids can. The keratolytic action of urea works by breaking down the excess, non-living layers of the stratum corneum (the outermost skin). It helps normalize skin cell turnover, not destroy healthy tissue. It removes the unhealthy, thick, scaly buildup, revealing the healthier skin underneath, but does not thin the living dermal layers.
Yes, a temporary, mild stinging or burning sensation can be a normal side effect when first applying Axera, especially on very dry, cracked, or sensitive skin. This feeling usually decreases as your skin becomes more hydrated and healed. If the stinging is severe, lasts for a long time, or is accompanied by a rash, stop using the product and consult your healthcare provider.
Yes, Axera is highly effective for treating cracked heels. The hard, thick skin (callus) that often forms on heels is a perfect target for urea's keratolytic and hydrating properties. The cream works to soften and break down the callus while deeply moisturizing the new skin underneath, helping to heal the cracks and prevent them from returning with regular use. Be sure not to apply it to actively bleeding cracks.
Whether you need a prescription for a urea-based cream like Axera depends on the concentration of urea in the product. Lower concentrations are often available over-the-counter (OTC), while higher, more potent concentrations typically require a prescription from a healthcare provider. The product data for Axera on IsraelPharm indicates it is an OTC product, meaning a prescription is not required for purchase.
No, Axera is not an antifungal medication and should not be used to treat fungal infections like athlete's foot or ringworm. Axera is designed to moisturize and soften skin. Using it on a fungal infection could create a more moist environment, which might worsen the infection. If you suspect you have a fungal infection, you need to use a specific antifungal cream to treat it effectively.
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