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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Bosulif (Bosutinib) is a targeted oral therapy for adults diagnosed with Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML). It is used for both newly-diagnosed patients and those who have been previously treated with other medications.
| Bosulif Brand | 500mg 28 Tablets |
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Our price: $3,610.00 |
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| Bosulif Brand | 400mg 28 Tablets |
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Our price: $3,200.00 |
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| Bosulif Brand | 100mg 28 Tablets |
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Our price: $1,240.00 |
Bosulif is a prescription medication used to treat a type of cancer known as Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML). It belongs to a class of drugs called tyrosine kinase inhibitors (TKIs). As a targeted therapy, it is designed to specifically attack the cancer cells while minimizing damage to healthy cells in the body, making it a powerful tool in managing this specific form of leukemia.
Bosulif works by blocking the activity of a specific protein called the Bcr-Abl tyrosine kinase. This protein is found in the cancer cells of patients with Ph+ CML and is responsible for signaling these cells to grow and divide uncontrollably. By inhibiting this protein, Bosulif effectively stops the growth of the leukemic cells and can lead to a reduction in their numbers, helping to manage the progression of the disease.
Bosulif is intended for adult patients who have been diagnosed with Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML). It is approved for individuals who are newly diagnosed with the chronic phase of the disease. It is also an appropriate treatment option for patients in the chronic, accelerated, or blast phases of Ph+ CML who have already been treated with at least one other tyrosine kinase inhibitor but it did not work or is no longer a suitable option.
The administration of Bosulif should be done exactly as prescribed by your healthcare provider. It is typically taken orally as a tablet once per day with a meal. Your specific dosage will be determined by your doctor based on your medical condition, stage of the disease, and response to treatment. It is important not to crush, break, or chew the tablet, and to swallow it whole. Never alter your dose or stop taking the medication without first consulting your doctor.
Like all medications, Bosulif may cause side effects, although not everyone will experience them. Common side effects can include diarrhea, nausea, stomach pain, vomiting, fatigue, and rash. More serious side effects require immediate medical attention. These can include signs of liver problems like yellowing skin or dark urine, symptoms of blood disorders like easy bruising or fever, heart problems, or severe skin reactions. A full list of potential side effects should be discussed with your doctor.
Choosing IsraelPharm for your medication needs ensures you receive authentic, brand-name Bosulif manufactured by Pfizer at competitive prices. We are committed to providing a seamless and secure online ordering process, with licensed pharmacists available to answer your questions. Our reliable international shipping brings your essential medication directly to your door, offering a convenient and cost-effective solution for your long-term treatment plan without compromising on quality or safety.
Like any medication, Bosulif® can cause side effects. It is important to be aware of them, but you may not experience any. Contact your doctor immediately if you experience any of the following serious side effects:
Bosulif® (Bosutinib) is a targeted therapy for the treatment of adult patients with:
You should take Bosulif orally once a day with a meal. Swallow the tablet whole with a glass of water; do not crush, break, or chew it. Consistency is key, so try to take it at the same time each day to maintain a steady level of the medication in your body. Always follow the specific instructions provided by your oncologist.
If you miss a dose of Bosulif, take it as soon as you remember on the same day. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one, as this can increase your risk of side effects.
You should avoid eating grapefruit or drinking grapefruit juice while taking Bosulif. Grapefruit products can interfere with how the medication is absorbed and processed by your body, potentially leading to increased levels of the drug and a higher risk of serious side effects. Always discuss your diet with your doctor when starting a new medication.
The time it takes for Bosulif to show results can vary from person to person. Your doctor will monitor your progress through regular blood tests to check your blood counts and the levels of the Philadelphia chromosome. While some patients may see improvements within a few months, it can take longer for others. Consistent treatment is crucial for the best outcome.
The most common side effects of Bosulif include diarrhea, nausea, vomiting, stomach-area pain, rash, fever, and fatigue. These are often most noticeable when you first start the medication. Your doctor can provide advice on how to manage these side effects, which may lessen over time as your body adjusts to the drug.
Yes, Bosulif can potentially cause liver problems. Your doctor will monitor your liver function with regular blood tests before and during your treatment. Contact your doctor immediately if you experience symptoms like yellowing of your skin or the whites of your eyes (jaundice), dark urine, tiredness, or pain in the upper right part of your stomach.
Bosulif may cause heart-related problems in some patients, including fluid retention and changes in the heart's electrical activity (QT interval prolongation). Inform your doctor if you have a history of heart conditions. Seek medical attention if you experience chest pain, swelling in your ankles or legs, shortness of breath, or feel faint while taking this medication.
No, you should never stop taking Bosulif without consulting your oncologist, even if you feel well and your symptoms have improved. Chronic myelogenous leukemia requires long-term management to keep the cancer cells under control. Stopping treatment can allow the leukemia cells to multiply again, potentially causing the disease to progress or become resistant to treatment.
Store Bosulif tablets at room temperature, away from excessive heat, moisture, and direct sunlight. Keep the bottle tightly closed and in a location that is out of reach of children and pets. Do not store it in the bathroom, as the humidity can affect the medication. Proper storage ensures the medicine remains safe and effective.
Before you start taking Bosulif, you must inform your doctor about your complete medical history. Be sure to mention any liver, kidney, or heart problems, any history of hepatitis B, any bleeding or bruising issues, and if you are pregnant, planning to become pregnant, or breastfeeding. Also, provide a list of all other medications you take, including supplements.
Yes, Bosulif can interact with many other medications, which can affect how it works or increase your risk of side effects. It is very important to tell your doctor about all drugs you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Specifically mention any anticoagulants, antifungals, antibiotics, or seizure medications.
While uncommon, Bosulif can cause serious skin reactions. You should contact your doctor immediately if you develop a severe, painful red or purplish rash that spreads and starts to blister, or if you notice lesions appearing in your mouth or on your lips. These could be signs of a rare but dangerous condition that requires urgent medical attention.
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