Arava ^*

What is Arava?

Arava is the brand name for the medication leflunomide, an oral disease-modifying antirheumatic drug (DMARD) prescribed to treat adults with active rheumatoid arthritis and psoriatic arthritis. It belongs to a class of drugs known as pyrimidine synthesis inhibitors, which work on the immune system to slow the progression of the disease. Unlike basic pain relievers, Arava targets the underlying autoimmune processes that cause inflammation, joint pain, and stiffness, helping to prevent long-term joint damage and improve physical mobility.

How does Arava work?

Arava works by blocking an enzyme called “dihydroorotate dehydrogenase,” which is essential for the creation of DNA building blocks (pyrimidines) in your body’s rapidly dividing cells. By inhibiting this enzyme, Arava specifically targets overactive immune cells (lymphocytes) that are responsible for attacking the joints in rheumatoid arthritis. This action calms the immune system, leading to a significant reduction in the inflammation and swelling that cause pain and joint erosion, thereby slowing down the disease’s progression and preserving joint function over time.

Who is Arava for?

Arava is for adults diagnosed with moderate to severe active rheumatoid arthritis or active psoriatic arthritis. It is often prescribed when other medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), have not provided enough relief. Because it modifies the disease process itself, Arava is intended for patients who need to slow down joint damage and improve their long-term physical function. It is not a simple painkiller but a long-term treatment. Your doctor will perform tests to ensure it is a safe and appropriate choice for your specific health profile.

Dosage and administration

Arava is administered as an oral tablet, typically taken once per day, with or without food, as directed by your healthcare provider. Treatment may begin with a “loading dose,” which is a higher initial dose for the first few days to help the medication build up in your body more quickly, followed by a lower daily maintenance dose. The exact dosage is determined by your doctor based on your medical condition, response to treatment, and other factors. It is crucial to take Arava consistently and exactly as prescribed to achieve the best results.

Side effects

While Arava is effective for many, it may cause side effects in some individuals, ranging from mild to severe. Common side effects can include diarrhea, nausea, stomach pain, headache, hair loss, and a skin rash. Though less common, more serious side effects can occur and require immediate medical attention. These include signs of liver problems (dark urine, yellowing eyes/skin), severe high blood pressure, nerve damage (numbness or tingling in hands/feet), signs of a serious infection (fever, chills), or new or worsening cough or shortness of breath. Always discuss any side effects with your doctor.

Why buy from IsraelPharm?

Buying your Arava from IsraelPharm ensures you receive genuine, brand-name medication sourced from a licensed and regulated supply chain at a competitive price. We make managing your rheumatoid arthritis more affordable by connecting you with authentic pharmaceuticals without the high markups often seen in the US market. Our streamlined online ordering process, dedicated customer support, and reliable shipping provide a convenient and trustworthy way to access the medications you need to maintain your health and quality of life.