Tepezza ^*

Tepezza may begin to show effects within a few weeks of the first infusions. Many patients report noticeable improvements in eye bulging and double vision after the second or third infusion, which occurs around week six. The full benefits of the treatment are typically seen after completing the full course of eight infusions over about five months.

Tepezza is used to treat Thyroid Eye Disease, an autoimmune condition linked to Graves' disease. In TED, your immune system mistakenly attacks the muscle and fat tissue behind your eyes. This causes inflammation, leading to symptoms like eye bulging (proptosis), double vision, pain, and swelling. Tepezza targets the underlying cause of this process.

Tepezza is not a form of chemotherapy. It is a targeted therapy called a monoclonal antibody. Unlike chemotherapy, which affects many cell types, Tepezza is designed to specifically block the IGF-1R protein that is overactive in Thyroid Eye Disease. This helps reduce inflammation without the broad effects of a chemo drug.

Tepezza can increase blood sugar levels, which requires careful management for patients with diabetes or pre-diabetes. Your doctor will need to monitor your blood sugar closely before, during, and after your treatment course. Adjustments to your diabetes medication may be necessary to maintain safe glucose levels while you are receiving Tepezza infusions.

Tepezza works best when infusions are given on a consistent schedule of once every three weeks. If you miss a scheduled appointment, you should contact your healthcare provider as soon as possible. They will work with you to reschedule your infusion and adjust your treatment plan to ensure you get the best possible results from the therapy.

Tepezza may cause hair thinning or hair loss in some patients, but this side effect is typically temporary. In most cases, hair begins to grow back after the treatment course is completed. If you experience significant or concerning hair loss while taking Tepezza, discuss it with your doctor for management advice and reassurance.

Tepezza has been shown to provide long-lasting reduction in eye bulging and double vision for many patients with Thyroid Eye Disease. Clinical studies have shown that the improvements seen after a full treatment course are often sustained over time. However, individual results can vary, and you should discuss long-term expectations with your specialist.

Tepezza is not recommended for women who are pregnant or planning to become pregnant, as it may cause harm to a developing fetus. Women of childbearing potential should use effective contraception before starting, during, and for at least six months after the final dose of Tepezza. Discuss your family planning with your doctor before starting treatment.

Tepezza is a specialty medication that must be handled by a healthcare professional in a clinical setting. It requires refrigeration and careful preparation before being administered as an intravenous infusion. You will not need to worry about storing Tepezza at home, as it will be managed entirely by your infusion center or hospital.

Tepezza may cause infusion-related reactions, which are similar to an allergic response. Symptoms can include shortness of breath, a fast heartbeat, high blood pressure, and muscle pain. These reactions most often occur during the infusion itself. Your healthcare team will monitor you closely during each treatment to manage any potential reactions promptly and safely.

Tepezza may cause hearing-related side effects, including hearing loss or ringing in the ears (tinnitus). Your doctor might recommend a hearing test before you start treatment and monitor your hearing throughout. You should report any changes in your hearing to your doctor immediately, as they may need to adjust your treatment plan.

Tepezza can potentially cause or worsen inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis. Patients with a history of IBD must inform their doctor before starting treatment. If you develop symptoms like ongoing diarrhea, abdominal pain, or blood in your stool during treatment, report them to your doctor right away.

Tepezza is a specialized treatment for Thyroid Eye Disease and is typically prescribed by an ophthalmologist (an eye specialist) or an endocrinologist (a hormone specialist). These doctors have the expertise to diagnose TED and determine if Tepezza is the appropriate course of treatment for your specific condition and symptoms.

Tepezza does not require extensive preparation on your part. Your healthcare provider will give you specific instructions, which may include drinking plenty of water and eating a normal meal before your appointment. You should also provide a full list of your current medications and health conditions to your doctor before your first infusion.