For visual reference only; actual product may vary
For visual reference only; actual product may vary
Orencia contains abatacept, a biologic medication that modifies the immune system. It reduces inflammation and joint damage for adults with rheumatoid or psoriatic arthritis and children with polyarticular juvenile idiopathic arthritis. This product requires cold shipping.
| Orencia Brand | 125mg 4 Pre-Filled Syringe |
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Our price: $1,220.00 |
Orencia is a prescription biologic medication used to treat several autoimmune conditions. Its active ingredient is abatacept. It is primarily prescribed for adults with moderate to severe rheumatoid arthritis or psoriatic arthritis. Orencia is also used for polyarticular juvenile idiopathic arthritis in children. This medication helps reduce underlying inflammation. It aims to prevent joint damage and improve physical function over time. It is considered a long-term management therapy.
Orencia works by targeting a specific part of the immune system. It is a selective T-cell costimulation modulator. T-cells are a type of white blood cell involved in inflammation. For T-cells to become fully active and attack the body’s own tissues, they need two signals. Orencia blocks the second signal. It does this by binding to proteins called CD80 and CD86 on the surface of other immune cells. By preventing this connection, Orencia stops T-cells from activating. This reduces the inflammatory process that causes joint pain, swelling, and damage in autoimmune arthritis.
Orencia is for patients with certain inflammatory autoimmune disorders. It is approved for adults with moderate to severe rheumatoid arthritis (RA). Many of these patients have not responded well to other treatments. It is also used for adults with active psoriatic arthritis (PsA) to help with both joint and skin symptoms. Furthermore, Orencia can be prescribed for children aged two years and older. These children have moderate to severe polyarticular juvenile idiopathic arthritis (pJIA). A rheumatologist will determine if Orencia is a suitable treatment based on the specific condition, disease activity, and medical history.
Orencia dosage and administration depend on the patient and the condition being treated. The medication is given as a subcutaneous injection (under the skin) or an intravenous (IV) infusion. The subcutaneous injection is typically administered once a week, on the same day each week. The usual dose for adults is 125 mg. Patients can be taught to inject it themselves at home using a pre-filled syringe or autoinjector. The IV infusion is administered by a healthcare professional. Dosing for IV infusions is based on body weight. If you miss a dose, take it as soon as you remember. Do not take two doses at the same time to make up for a missed one.
Orencia may cause side effects, though not everyone experiences them. The most common side effects are usually mild. They can include headaches, nausea, and upper respiratory tract infections like a cold. Some people experience reactions at the injection site, such as redness or itching. While less common, serious side effects are possible. Orencia affects the immune system, which can increase the risk of serious infections. Symptoms of a serious infection include fever, chills, or a persistent cough. In rare cases, severe allergic reactions can occur. It is important to discuss all potential risks with your doctor before starting treatment.
IsraelPharm offers a reliable and affordable way to get your prescription medications. We provide authentic Orencia manufactured by Bristol Myers. Our platform makes it easy to order your treatment from the comfort of your home. We are dedicated to providing excellent customer service and support. Our pharmacy team can help answer your questions. We ensure that your medication is sourced, stored, and shipped according to the highest standards. You receive the same quality medication you would from a local pharmacy but at a more competitive price. Trust IsraelPharm for your long-term health needs.
Always consult your doctor for medical advice about side effects. This list is not exhaustive.
Most common side effects are mild to moderate.
Contact your doctor immediately if you experience any of these.
Orencia is prescribed for a range of immune-mediated joint conditions.
This is an autoimmune disease where the immune system attacks joint linings. It causes inflammation, pain, and can lead to permanent damage.
In PsA, the immune system causes inflammation in both the skin and joints. Orencia can help manage joint and skin symptoms.
Orencia is used for this condition in children aged two and older. It involves arthritis in five or more joints.
Orencia does not provide immediate relief, as it works to gradually control the underlying inflammation. Some patients may start to notice an improvement in their symptoms within a few weeks of starting treatment. However, it can take up to three months or longer to experience the full benefits of the medication. It is important to continue taking Orencia as prescribed by your doctor, even if you do not see immediate results.
If you miss your weekly subcutaneous injection of Orencia, you should take it as soon as you remember. Then, take your next dose on your regularly scheduled day. If it is already time for your next scheduled dose, skip the missed one. Do not take two doses of Orencia at the same time to make up for a missed dose. Maintaining a consistent schedule is important.
Orencia does not have a direct, major interaction with alcohol. However, both alcohol and some arthritis conditions can affect the liver. Since biologic medications like Orencia are processed in the body, it is wise to be cautious. Moderate alcohol consumption is generally considered safe, but you should discuss your alcohol use with your doctor. They can provide advice based on your overall health and other medications you take.
Orencia must be stored in the refrigerator at a temperature between 36°F and 46°F (2°C to 8°C). It should be kept in its original carton to protect it from light. Do not freeze the medication. If the syringe or autoinjector freezes, it must not be used. Before injection, the medication can be left at room temperature for about 30 minutes to make it more comfortable to administer.
Orencia can be taken with other non-biologic medications for arthritis, such as methotrexate, NSAIDs, or steroids. However, Orencia should not be used at the same time as other biologic DMARDs (like TNF inhibitors) or Janus kinase (JAK) inhibitors. Combining these powerful immune-suppressing drugs can significantly increase your risk of serious infections. Always inform your doctor of all medications you are taking before starting treatment.
Hair loss is not listed as a common side effect of Orencia in clinical trials. The underlying autoimmune conditions, such as rheumatoid arthritis, or other medications taken for these conditions, like methotrexate, are more commonly associated with hair loss. If you experience significant hair thinning while taking Orencia, discuss it with your rheumatologist to determine the likely cause and explore possible solutions.
Orencia may affect your immune system's response to vaccinations. It is recommended that you be up-to-date with all required immunizations before you start your treatment. You should not receive live vaccines while you are taking Orencia. Inactivated vaccines, like the flu shot, are generally considered safe and recommended. Always consult with your doctor before receiving any vaccine to ensure it is appropriate for you.
Orencia use during pregnancy has not been extensively studied, so it should be avoided unless the potential benefit justifies the potential risk to the fetus. If you are planning to become pregnant, you should discuss the risks and benefits with your doctor. They may recommend stopping the medication for a period before you try to conceive. It is important to use effective contraception while you are being treated with Orencia.
Because Orencia affects your immune system, it is important to know the signs of an infection. You should contact your doctor if you develop symptoms such as a fever, chills, a persistent cough, shortness of breath, or burning during urination. Also watch for sores on your body, muscle aches, or significant fatigue. Promptly reporting these symptoms allows for early diagnosis and treatment, which is crucial when your immune response is suppressed.
The subcutaneous form of Orencia is designed for easy self-administration at home. It comes in a pre-filled syringe or a ClickJect autoinjector. Your healthcare provider will teach you how to properly inject the medication into your thigh or abdomen. You should rotate injection sites with each dose to avoid skin irritation. Before injecting, allow the medication to sit at room temperature for 30 minutes for a more comfortable experience.
Orencia is administered as an injection or infusion, not as an oral medication. Therefore, it does not need to be taken with or without food. You can eat your meals as you normally would on the day of your treatment. The effectiveness and absorption of the medication are not affected by food. Some people may experience mild nausea as a side effect, but this is not typically related to meals.
Orencia is specifically FDA-approved for rheumatoid arthritis, psoriatic arthritis, and polyarticular juvenile idiopathic arthritis. While it works by targeting the immune system, its use for other autoimmune conditions is considered off-label. Your doctor will determine if Orencia is the right medication for your specific diagnosis. It has been studied in other conditions, but its safety and effectiveness have not been established for those uses.
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