Derma‑Smoothe/FS (
fluocinolone acetonide) is a
topical corticosteroid available as a 0.01% oil, used for treating
psoriasis of the scalp in adults. As a low-to-medium potency steroid, it has
anti‑inflammatory, anti‑itching, and vasoconstrictive properties. It works by
reducing immune activity and inflammation in affected skin, calming redness, scaling, and discomfort. The oil is designed to apply easily through hair onto the scalp. Users dampen the scalp, apply a thin film, massage gently, then cover with a shower cap and leave overnight or at least 4 hours before rinsing.
This formulation contains refined peanut oil, heavily purified and tested to contain minimal peanut protein. It is supplied in 4‑ounce (120mL) bottles along with two disposable shower caps. Derma‑Smoothe/FS is only for external use and should not be used inside the mouth, eyes, or genital regions. Its use is stopped when the scalp psoriasis is controlled or discontinued if no improvement is seen within two weeks. It does not treat infections of the nails or scalp and should not be swallowed.
Dosage
It is important to follow the dosage instructions printed on the label of the box. Check with a doctor or pharmacist if there are any doubts regarding the proper dosage and treatment regimen.
- Adults with scalp psoriasis: Apply a thin layer of oil to wet or damp scalp once daily. Massage well and cover with the provided shower cap. Leave on overnight or at least 4 hours, then wash off with shampoo.
- Discontinue after scalp condition is controlled within two weeks, or consult provider if no improvement.
Wash hands before and after application. Do not apply more than directed. If a dose is missed, apply when remembered unless close to next scheduled application. Do not double-apply.
Storage
Store Derma‑Smoothe/FS oil at room temperature between 20-25 °C (68-77 °F). Keep the bottle tightly closed. Protect it from heat and moisture. Avoid storing it in bathrooms. Keep out of reach of children and pets. Do not use past the expiration date on the package.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.
The patient leaflet provides full details about possible side effects. If any questions arise, discuss them with a medical provider before starting treatment.
Caution
If symptoms of a sudden severe allergic reaction occur after application of Derma-Smoothe, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.
Pregnant women should use Derma‑Smoothe/FS oil cautiously. If used during pregnancy, it should be applied to the smallest area of skin and for the shortest possible duration. Breastfeeding women should avoid applying directly to the nipple or areola area to minimize exposure to the infant.
Most users will not experience serious side effects when used properly. Some local reactions may occur, especially with extended or occluded use.
Common side effects reported include:
- Mild burning or stinging
- Dryness of the skin
- Irritation or hypopigmentation
If any side effects persist or worsen, consult a healthcare provider.
Derma‑Smoothe/FS oil is approved for psoriasis of the scalp in adults. Scalp psoriasis causes red, scaly, sometimes itchy or painful patches on the scalp. The oil reduces inflammation and itching, helping to relieve plaque thickness and improve scalp appearance.
The medication is not approved for other skin areas such as the face, armpits, groin, or diaper regions, unless specifically directed by a physician. Use in these areas increases the risk of local side effects like thinning skin, stretch marks, or spider veins (telangiectasia).
Some healthcare providers may prescribe Derma‑Smoothe/FS oil off-label for atopic dermatitis in adults or older children (≥ 2 years), applying thinly twice daily for up to 4 weeks. Off‑label use requires close monitoring for side effects and slowing treatment once skin improves.