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For visual reference only; actual product may vary

  • US Name:

    Letairis

  • Alternative Names:

    Volibris

  • Active Ingredients:

    Ambrisentan

  • Brand Manufacturer:

    GSK

  • Manufacturer Location:

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Letairis *

For visual reference only; actual product may vary

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Letairis (ambrisentan) is a prescription oral tablet used to treat pulmonary arterial hypertension (PAH). This medication works by relaxing blood vessels in the lungs, which helps lower blood pressure and reduce strain on the heart. It can improve your ability to be physically active.

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Volibris Brand 10mg
30 Tablets
-
+
Our price:
$1,300.00
Volibris Brand 5mg
30 Tablets
-
+
Our price:
$1,275.00

*Please note all prices are in US dollars

What is Letairis?

Letairis is an endothelin receptor antagonist prescribed for treating pulmonary arterial hypertension (PAH). This is a serious condition where blood pressure in the arteries of the lungs is too high. Letairis contains the active ingredient ambrisentan. It works to make breathing easier and help you be more active. Over time, high pressure in the lungs can strain your heart. The main goal of Letairis is to lower this pressure. This reduces the workload on the heart. It improves blood flow and reduces symptoms like shortness of breath and fatigue. This medication is for adults and is not approved for use in children. Due to significant risks, it is only available through a special safety program.

How does Letairis work?

Letairis works by blocking a natural substance in the body called endothelin-A. This substance is responsible for tightening the blood vessels in the lungs. When blood vessels tighten, blood pressure inside them increases. Letairis specifically targets and blocks the receptors that endothelin binds to. This action allows the muscular walls of the pulmonary arteries to relax and widen. As the vessels open up, there is less resistance to blood flow. This lowers the blood pressure in the lungs. The heart does not have to pump as hard to move blood through the lungs. This process improves oxygen supply and can enhance exercise capacity. Combining Letairis with other PAH drugs like tadalafil may offer even greater benefits.

Who is Letairis for?

Letairis is for adults who have been diagnosed with pulmonary arterial hypertension (PAH). It is prescribed to help manage symptoms and improve quality of life. Patients who experience fatigue or shortness of breath during physical activity may benefit. It can help increase exercise ability and slow down the worsening of the disease. However, Letairis is not suitable for everyone. It must not be taken by anyone who is pregnant because it causes severe birth defects. Women who are able to become pregnant must use two reliable forms of birth control during treatment. They must also continue for one month after their last dose. All patients must enroll in a mandatory safety program (REMS) to receive this medication.

Dosage and administration

Letairis is usually taken as a once-daily oral tablet. You should follow your doctor’s instructions carefully for the correct dose. The tablet can be consumed with or without a meal. It is important to swallow the tablet whole. Do not crush, split, or chew Letairis tablets. Taking the medication at the same time each day helps maintain a consistent level in your body. If you happen to miss a dose, take it as soon as you remember on that same day. However, never take two doses at once to make up for a missed dose. Your doctor will determine the appropriate dose for your specific condition and may adjust it based on your response to treatment.

Side effects

Letairis may cause side effects, although many people experience only mild ones or none at all. The most commonly reported side effects include swelling in the hands, ankles, and feet due to fluid retention. Other potential side effects are nasal congestion or a stuffy nose, sinus irritation, and skin flushing or redness. More serious side effects can occur. Letairis carries a strong warning about the risk of severe birth defects and should never be used during pregnancy. It can also potentially cause liver problems or a drop in sperm count in men. If you experience signs of an allergic reaction like swelling of the face or throat, seek emergency medical help immediately.

Why buy from IsraelPharm?

IsraelPharm offers a safe, convenient, and affordable way to purchase your prescription medications like Letairis. We source our products only from licensed manufacturers and regulated pharmacies, ensuring you receive genuine medication every time. Our streamlined online platform makes it simple to order your refills from the comfort of your home. By avoiding the high overhead costs of traditional pharmacies, we pass significant savings on to you. Our dedicated customer support team is available to assist you with any questions or concerns. Experience the peace of mind that comes with reliable, direct-to-your-door service for your essential treatments.

Most people do not experience major side effects. However, some common side effects of Letairis may include:

  • Swelling of the hands, ankles, legs, or feet (fluid retention)
  • Nasal congestion, stuffy nose, or sinus irritation
  • Flushing (redness of the face or skin)
  • Headache

Serious side effects can occur. Seek immediate medical attention for signs of a severe allergic reaction, such as facial swelling, hives, or difficulty breathing. Letairis carries a major risk of birth defects and is not safe for use during pregnancy.

Letairis (ambrisentan) is used to treat:

  • Pulmonary arterial hypertension (PAH)

By lowering blood pressure in the lungs, it helps to relieve associated symptoms such as:

  • Shortness of breath, especially with activity
  • Tiredness and fatigue
  • Chest pain or pressure
  • Swelling in the ankles, legs, or feet
  • Reduced ability to exercise

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