How quickly does Litfulo work?

Hair regrowth with Litfulo may begin within 12 to 24 weeks of starting therapy. Some users may notice initial hair improvement earlier, but significant growth typically requires several months. Treatment response varies based on disease extent and individual factors. Ongoing monitoring by a healthcare provider helps guide continued use or adjustment based on progress.

Is Lifulo safe for long‑term use?

Litfulo may be used long‑term under medical supervision, but its use requires regular evaluation of benefits and risks. Periodic blood tests for infection risk, cholesterol, liver enzymes, and blood counts are essential. Long-term use may increase susceptibility to infections or other immune-related side effects. The decision to continue therapy beyond a year depends on individual response and health considerations in consultation with a specialist

How does ritlecitinib work?

Ritlecitinib is an oral JAK3 and TEC kinase inhibitor that reduces inflammation by blocking key enzymes around hair follicles. This targeted action suppresses the immune attack causing hair loss in alopecia areata and allows hair regrowth to occur. Because it is taken orally, it affects hair follicles systemically rather than being a topical treatment.

Can ritlecitinib be used with other arthritis medications?

Yes. Ritlecitinib may be used alone or in combination with non-biologic DMARDs such as methotrexate. Concurrent use with biologic DMARDs or strong immunosuppressants is generally not recommended due to increased infection risk. A healthcare provider will evaluate the patient’s full treatment plan to ensure safe and effective combination therapy

How does Litfulo help regrow hair in alopecia areata?

Litfulo reduces inflammation in hair follicles by inhibiting specific enzymes (JAK3 and TEC) responsible for immune attack. When the immune response calms, hair follicles can recover function and produce new hair. Over time, continued enzyme suppression allows gradual hair regrowth in affected areas such as scalp, eyebrows, eyelashes, or other patches.

What areas of hair loss can Litfulo treat?

Litfulo is used to treat severe hair loss in alopecia areata, which may affect the scalp, eyebrows, eyelashes, and body hair. It aims to reduce inflammation and support regrowth across all these areas. Treatment results vary, and hair regrowth may be patchy or gradual. Specialists monitor progress and may adjust therapy based on response in different regions.

Can Litfulo be used in adolescents?

Yes. Litfulo is approved for use in adolescents aged 12 years and older with severe alopecia areata. Safety and effectiveness have been evaluated in this age group, with dosing similar to adults. Ongoing medical follow-up is important to track hair regrowth, monitor for side effects, and assess overall development during treatment.

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For visual reference only; actual product may vary

US Name:

Litfulo
Alternative Names:

Litfulo
Active Ingredients:

Ritlecitinib
Brand Manufacturer:

Pfizer
Manufacturer Location:

Germany
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Litfulo ^*

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Litfulo can be used to treat severe alopecia areata in adults and adolescents.

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Litfulo Brand	50mg 28 Tablets	- Litfulo – Brand, Litfulo, 50mg, 28, Tablets, 24875, Pfizer, 2715 + 0	Our price: $1,015.00

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Description
Side Effects
Indications
FAQ
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Litfulo (generic name: ritlecitinib) is an oral Janus kinase 3 (JAK3) and TEC family kinase inhibitor used to treat severe alopecia areata in adults and adolescents aged 12 years and older. Alopecia areata is an autoimmune condition where the immune system attacks hair follicles, causing inflammation and hair loss on the scalp, face, and other body areas. Ritlecitinib works by inhibiting JAK3 and TEC enzymes, which play a central role in the inflammatory process around hair follicles. This reduction of inflammation promotes hair regrowth, helping restore hair in affected areas. By targeting these specific enzymes, Litfulo reduces immune attack on the follicles without broadly disrupting the immune system. Litfulo belongs to the pharmacological class of medicine used in autoimmune conditions. Oral administration allows for a focused treatment that combines convenience with precision, supporting hair regrowth in individuals affected by severe alopecia areata.

Dosage

It is important to follow the dosage instructions printed on the label of the box. Check with a doctor or pharmacist if there are any questions regarding the proper dosage and treatment regimen. The standard dosage of Litfulo is 50 mg taken orally once daily, with or without food. The capsule should be swallowed whole with water. If a dose is missed, it should be taken as soon as remembered on the same day; if it is close to the next scheduled dose, skip the missed dose and continue the regular dosing schedule. Patients with moderate to severe liver or kidney impairment may require dosage adjustment or monitoring by a healthcare provider.

Storage

Avoid storing near heat sources or in humid areas, such as bathrooms. Litfulo capsules should be kept in their original packaging and protected from moisture and light, and stored at room temperature between 20-25 °C (68 -77 °F).

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.

Read the information leaflet that comes with the medication.

Most people who use Litfulo do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include upper respiratory tract infections, headache, nasopharyngitis, and diarrhea, which are generally mild to moderate in intensity.

Due to immune modulation, there is also a risk of more serious infections, such as pneumonia or tuberculosis.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Litfulo is approved for severe alopecia areata in individuals aged 12 years and older. In this autoimmune disorder, the immune system mistakenly attacks hair follicles, resulting in sudden hair loss on the scalp, face, eyebrows, eyelashes, or other body parts. By reducing key inflammatory enzymes around the follicles, Litfulo helps restore hair growth and improve hair density. Treatment should occur under specialist medical supervision to monitor response and manage potential effects.

Hair regrowth with Litfulo may begin within 12 to 24 weeks of starting therapy. Some users may notice initial hair improvement earlier, but significant growth typically requires several months. Treatment response varies based on disease extent and individual factors. Ongoing monitoring by a healthcare provider helps guide continued use or adjustment based on progress.
Litfulo may be used long‑term under medical supervision, but its use requires regular evaluation of benefits and risks. Periodic blood tests for infection risk, cholesterol, liver enzymes, and blood counts are essential. Long-term use may increase susceptibility to infections or other immune-related side effects. The decision to continue therapy beyond a year depends on individual response and health considerations in consultation with a specialist

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