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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Cimzia (Certolizumab Pegol) is a prescription biologic medication used to treat adults with inflammatory autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and Crohn’s disease. By reducing inflammation, it helps manage symptoms effectively. This is a cold-chain product requiring special shipping.
| Cimzia Brand | 200mg/mL 2 Pre-Filled Syringes |
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Our price: $1,400.00 |
Cimzia is a brand-name biologic medication prescribed to adults for the treatment of several chronic inflammatory autoimmune conditions. Its active ingredient is Certolizumab Pegol, which belongs to a class of drugs known as Tumor Necrosis Factor (TNF) blockers. Cimzia is FDA-approved to manage symptoms in patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, and moderate to severe Crohn’s disease. These conditions are caused by an overactive immune system, leading to inflammation, pain, and tissue damage.
Cimzia works by specifically targeting and neutralizing a protein in your body called Tumor Necrosis Factor-alpha (TNF-alpha). In many autoimmune diseases, the body produces too much TNF-alpha, which triggers chronic inflammation and leads to the painful symptoms and joint or tissue damage associated with these conditions. By blocking the action of TNF-alpha, Cimzia helps to reduce this inflammation, providing symptom relief and potentially slowing the progression of the disease. Its unique molecular structure is “pegylated,” which helps it stay in the body longer, allowing for less frequent injections compared to some other treatments.
Cimzia is intended for adults who have been diagnosed with moderate to severe forms of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, or Crohn’s disease. It is typically prescribed when other foundational medications, have not provided adequate relief. This medication is suitable for patients who require a long-term treatment plan to manage chronic inflammation and improve their quality of life. A healthcare provider will determine if Cimzia is the right choice based on your specific condition, medical history, and previous treatments.
Cimzia is administered as an injection into the fatty tissue just under the skin (a subcutaneous injection), usually in the thigh or abdomen. The treatment typically begins with a series of starting doses, often 400 mg given at weeks 0, 2, and 4, to quickly bring symptoms under control. Following this initial period, treatment is continued with a lower maintenance dose, such as 200 mg every two weeks. Your doctor will provide the exact dosage schedule based on the condition being treated, and you may be trained to self-administer the injections at home for convenience.
The most common side effects associated with Cimzia include upper respiratory infections (like a cold), rash, headache, and nausea. Because Cimzia works by suppressing part of your immune system, there is an increased risk of developing serious infections, including tuberculosis (TB). Your doctor will test you for TB before you start treatment. In rare cases, a severe allergic reaction can occur. Seek immediate medical attention if you experience symptoms like hives, severe rash, trouble breathing, or swelling of your face, lips, or throat after your injection.
Choosing IsraelPharm for your Cimzia prescription provides a reliable and cost-effective way to access your medication. We source our pharmaceuticals from licensed suppliers, ensuring you receive genuine, high-quality medication at competitive prices. Our user-friendly online platform makes ordering simple and convenient, delivering your treatment directly to your door in discreet packaging. With a team of knowledgeable pharmacists available to answer your questions, IsraelPharm is committed to providing a safe, affordable, and supportive experience for managing your chronic condition.
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This information is for guidance only. Always consult your doctor or pharmacist before starting any new medication.
Common Side Effects:
Most people using Cimzia experience minimal to no side effects. Those that have been reported include:
Serious Side Effects:
Cimzia affects the immune system and can increase the risk of serious infections. Your doctor should evaluate you for tuberculosis (TB) before you begin treatment. Other serious side effects may involve new or worsening neurological diseases or certain types of cancer.
Allergic Reactions:
Seek immediate medical attention or call 911 if you experience signs of a severe allergic reaction after an injection, such as:
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any persistent or concerning symptoms.
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Cimzia is a prescription medication used to treat adults with several moderate to severe autoimmune conditions, including:
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While some patients may notice improvements within the first couple of weeks, it can take up to three months to feel the full benefits of Cimzia. The medication needs time to reduce the underlying inflammation in your body. It is important to continue with your prescribed dosing schedule and talk to your doctor about your progress, as response times can vary from person to person and by condition.
If you miss a dose of Cimzia, you should take it as soon as you remember. After that, you can return to your regular dosing schedule. Do not take a double dose to make up for the one you missed. If you are unsure what to do, it is best to contact your doctor or pharmacist for guidance on how to proceed with your treatment schedule.
Cimzia is given as a subcutaneous injection, meaning it is injected into the fatty layer of tissue under the skin, usually in the abdomen or thigh. Your healthcare provider will administer the first doses and may train you on how to self-inject at home. The pre-filled syringes are designed for patient use, making it a convenient option for long-term treatment.
Cimzia must be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Keep it in its original carton to protect it from light and do not freeze it. If you are traveling, it can be kept at room temperature (up to 25°C or 77°F) for a single period of up to 7 days. If not used within 7 days at room temperature, it must be discarded.
You should not receive "live" vaccines while being treated with Cimzia, as they can cause serious infections. Live vaccines include the measles, mumps, and rubella (MMR) and chickenpox vaccines. It is recommended to be up-to-date with all vaccinations before starting Cimzia. Inactivated vaccines, like the flu shot, are generally considered safe. Always discuss your vaccination plans with your doctor first.
Yes, before you start Cimzia, your doctor will run several tests to ensure it is safe for you. This includes screening for tuberculosis (TB), as Cimzia can reactivate a dormant infection. Your doctor will also likely order blood tests to check your liver function and blood cell counts. These precautions help minimize risks and confirm that Cimzia is an appropriate treatment for your condition.
Moderate alcohol consumption is not known to directly interact with Cimzia. However, both alcohol and some of the conditions Cimzia treats (like Crohn's disease) can affect the liver. Furthermore, Cimzia is often prescribed with other drugs like methotrexate, which can have significant liver-related side effects when combined with alcohol. It is always best to discuss your alcohol use with your doctor to be safe.
Cimzia has a unique structure. It is a "pegylated" antibody fragment, which means it has been modified to stay in the bloodstream longer. This allows for less frequent dosing schedules compared to some other anti-TNF medications. Its specific design allows it to target and neutralize TNF-alpha effectively while having this extended duration of action, offering a convenient and powerful treatment option for many patients.
Fatigue is a common symptom of the autoimmune diseases Cimzia is used to treat, such as rheumatoid arthritis and Crohn’s disease. While the medication works to reduce the disease activity causing this fatigue, some patients may still experience tiredness. It is not listed as one of the most common side effects of the drug itself, but if your fatigue worsens, you should discuss it with your doctor.
Cimzia is not directly linked to significant weight gain or loss as a side effect. However, for conditions like Crohn’s disease, effective treatment can lead to better nutrient absorption and appetite, potentially causing weight to return to a healthy normal. Conversely, feeling better and having less joint pain may lead to more physical activity and potential weight loss. Any major weight changes should be discussed with your doctor.
Yes, you can travel with Cimzia, but it requires careful planning to maintain its temperature. You should transport it in a cooler bag with ice packs to keep it refrigerated. If refrigeration is not possible, it can be kept at room temperature for up to seven days. Be sure to carry your prescription and a doctor's note, especially for air travel, to avoid any issues with security.
No, Cimzia is not chemotherapy. Chemotherapy drugs are designed to kill cancer cells rapidly, but they also affect other healthy cells in the body. Cimzia is a biologic therapy, also known as a targeted therapy. It works by targeting a specific protein (TNF-alpha) involved in the inflammation process of autoimmune diseases. This targeted action is different from the broad effects of chemotherapy.
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