For visual reference only; actual product may vary
For visual reference only; actual product may vary
Collagenase Santyl Ointment is a topical debriding agent used to remove dead tissue from chronic wounds like ulcers and severe burns. Its active enzyme, collagenase, cleans the wound bed, promoting a healthier environment for new tissue to grow and helping the healing process.
| Santyl Ointment Brand | 250 units/g 30 Grams |
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Our price: $164.00 |
 Allergy Pack | 30 Pouches 1 Pouch a Day | –+ | Our price: $73.95 | |
 Beauty Pack | 30 Pouches 1 Pouch a Day | –+ | Our price: $72.25 |
Santyl Ointment is a prescription topical medicine designed to clean and debride chronic skin wounds and severe burns. Its primary function is to remove dead, or necrotic, tissue from the surface of these wounds. By clearing away this non-viable tissue, the ointment helps to create a healthier wound environment, which is a critical step in allowing the body’s natural healing processes to take place and for new, healthy tissue to grow.
The ointment works through its active ingredient, an enzyme called collagenase. This enzyme specifically targets and breaks down denatured collagen, which is the primary component of the dead tissue found in chronic wounds. Collagenase selectively digests this necrotic debris without harming the healthy tissue A clean wound bed, free of dead tissue, is essential for healing, as it reduces the risk of infection and allows for the formation of new granulation tissue and skin cells.
Santyl Ointment is intended for patients who have chronic skin ulcers or severe burns where dead tissue is present. This includes individuals with conditions such as pressure ulcers (bedsores), diabetic foot ulcers, and venous leg ulcers. It is a key part of the wound care regimen for patients whose wounds are not healing properly due to the presence of this necrotic material. A healthcare provider will determine if Santyl is the right choice for a specific wound type.
The ointment should be applied as directed by your healthcare provider, which is typically once a day. Before application, the wound must be gently cleansed with a sterile saline solution to remove any loose debris. A thin layer of Santyl Ointment is then applied directly to the entire surface of the dead tissue. It’s important to confine the ointment to the wound area. After application, the wound is covered with a sterile dressing to protect it and keep the ointment in place.
The most commonly reported side effect is a temporary sensation of pain or burning at the site of application. Some patients may also experience redness, irritation, or inflammation of the skin surrounding the wound. These effects are usually mild and temporary. It is important to notify your doctor if these symptoms persist or worsen. Allergic reactions are rare but possible; seek immediate medical attention if you experience signs of a severe reaction, such as a rash, hives, or difficulty breathing.
IsraelPharm offers a reliable and affordable way to purchase your essential medications like Santyl Ointment. We are committed to providing authentic, brand-name products sourced from a licensed supply chain, ensuring you receive the same quality you would from a local pharmacy. With competitive pricing and dedicated customer service from our team of pharmacy experts, we make managing your wound care needs simple, secure, and cost-effective. Choose IsraelPharm for a trusted partner in your health journey.
Most side effects are localized to the application area. If any of these effects persist or worsen, contact your doctor. Common side effects may include:
Serious allergic reactions are rare. Seek immediate medical attention if you notice symptoms of a severe allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
Collagenase Santyl Ointment is indicated for the debridement of chronic dermal ulcers and severely burned areas. It helps remove dead tissue to promote wound healing in conditions such as:
Santyl Ointment begins working with the first application. The speed of visible results can vary depending on the size and severity of the wound, as well as the amount of dead tissue present. Consistent daily application is key to effectively cleaning the wound bed. You may begin to see a cleaner wound base within a few days to a week.
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and resume your regular once-daily schedule. Do not apply a double dose to make up for the missed one, as this can increase irritation without improving results.
You should avoid using certain other products with Santyl, especially antiseptics containing heavy metals like silver (e.g., silver sulfadiazine, silver nitrate) or mercury. These substances can inactivate the collagenase enzyme and make the ointment ineffective. Always consult your healthcare provider before applying any other product to the wound.
No, Santyl Ointment is not an antibiotic. It is an enzymatic debriding agent, meaning it cleans the wound by dissolving dead tissue. While this can help reduce the risk of infection by removing material where bacteria thrive, it does not kill bacteria directly. Your doctor may prescribe a separate antibiotic if an infection is present.
Santyl Ointment should be stored at room temperature, away from excessive heat and moisture. Do not freeze the ointment. Keep the tube tightly closed when not in use and store it out of reach of children and pets. Check the expiration date and discard any unused ointment after it has expired.
Some patients report a temporary feeling of pain or a burning sensation when Santyl Ointment is applied to the wound. This is a common side effect and is usually mild. If the pain is severe or does not go away, you should inform your healthcare provider, as they may suggest ways to manage this discomfort during application.
Occasionally, a wound may appear to get larger after starting treatment with Santyl. This is often a normal part of the process, as the ointment removes the dead tissue, revealing the true size of the underlying wound. This "uncovering" is a necessary step for proper healing to begin. Consult your doctor to confirm this is the case.
The black or yellowish material in a wound is called eschar or slough. It is composed of dead, non-viable tissue. Santyl Ointment is specifically designed to break down and liquefy this necrotic debris (a process called debridement), which is essential for allowing the healthy tissue underneath to heal properly.
Yes, Collagenase Santyl Ointment is a prescription medication. Its use requires supervision by a qualified healthcare professional who can properly diagnose the wound type and monitor the healing process. They will determine if Santyl is the appropriate treatment for your specific condition and provide instructions for its correct use.
Before each application, you should gently clean the wound with a sterile saline solution or another cleanser as directed by your doctor. Use a soft gauze pad to carefully remove any loose debris and slough that has been softened by the ointment from the previous application. Pat the area dry before applying a fresh layer of Santyl.
Santyl should be used with caution on actively bleeding wounds. The primary purpose of the ointment is to remove non-viable tissue, not to stop bleeding. If there is significant bleeding, it should be controlled before applying the ointment. Always follow your healthcare provider's specific instructions for your wound care.
Once the Santyl Ointment has successfully removed all the dead tissue and the wound bed appears clean and filled with healthy red granulation tissue, its use should be discontinued. Continuing to apply Santyl to a clean wound is not beneficial and may irritate the new, healthy cells. Your doctor will then direct the next phase of wound treatment.
The safety and effectiveness of Santyl Ointment in pediatric patients have not been fully established. Its use in children should only be under the direct supervision and prescription of a qualified healthcare provider who has determined that the potential benefits outweigh any potential risks for the child's specific condition.
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