For visual reference only; actual product may vary
For visual reference only; actual product may vary
Tagrisso (osimertinib) is a targeted therapy prescription medication used to treat non-small-cell lung cancer (NSCLC). It is specifically for patients whose cancer has certain epidermal growth factor receptor (EGFR) gene mutations. This medication works by blocking signals that cause cancer cells to grow and divide.
| Tagrisso Brand | 40mg 30 Tablets |
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Our price: $9,075.00 |
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| Tagrisso Brand | 80mg 30 Tablets |
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Our price: $9,075.00 |
Tagrisso is a prescription oral medication used to treat specific types of non-small-cell lung cancer (NSCLC). This medicine is a form of targeted therapy known as a kinase inhibitor. It is designed for lung cancers that have abnormal epidermal growth factor receptor (EGFR) genes. Tagrisso precisely targets the cancer cells with these mutations. This action helps to slow or stop the growth of the tumor. It is a third-generation EGFR inhibitor, often effective when others are not.
Tagrisso works by specifically targeting and blocking mutated EGFR proteins found in certain cancer cells. In some lung cancers, a mutated EGFR gene is always active. This sends constant signals for cells to grow and divide uncontrollably. Tagrisso attaches to this specific mutated protein. It effectively turns off the signal that promotes cancer cell growth. This targeted action avoids harming healthy cells as much as traditional chemotherapy might. It helps manage the cancer’s progression with high precision.
Tagrisso is for adults diagnosed with non-small-cell lung cancer that has spread to other parts of the body. A doctor must first confirm the presence of specific EGFR mutations through a genetic test. It can be prescribed as a first-line treatment for patients with certain EGFR mutations. It is also used for patients whose cancer has progressed after treatment with other EGFR-targeting drugs. This medication is suitable for those whose tumors have developed a specific T790M resistance mutation.
Tagrisso is typically taken as an 80 mg tablet once each day. Your doctor will determine the correct dose for your specific situation. You can take the tablet with or without a meal. It is important to swallow the tablet whole with a glass of water. Do not crush or chew it. If you have trouble swallowing, the tablet can be dissolved in water. Always follow your healthcare provider’s instructions carefully for the best results. Treatment often continues as long as the medication is effective or until side effects become unmanageable.
Tagrisso may cause side effects, but not everyone will experience them. It is important to discuss potential risks with your doctor. Some patients may experience mild to moderate side effects.
In rare cases, Tagrisso can cause more severe problems. A serious lung condition called interstitial lung disease (ILD) is a risk. Symptoms of ILD include new or worsening cough, fever, and trouble breathing. Heart problems and eye issues can also occur. Contact your doctor immediately if you experience any of these serious symptoms.
IsraelPharm offers a trustworthy and cost-effective way to get your prescribed Tagrisso medication. We understand the high cost of cancer treatment. We are committed to making it more affordable. You can save significantly compared to average U.S. retail prices. We ensure you receive genuine, brand-name medication directly from the manufacturer. Our streamlined ordering process and international delivery provide a simple and secure way to access your vital treatment from home. Our customer service team is ready to assist you with any questions.
Tagrisso can cause side effects ranging from mild to severe. You should review the full patient information leaflet included with your medicine. Contact your doctor if you experience concerning symptoms.
Tagrisso (osimertinib) is a targeted therapy used to treat certain types of non-small-cell lung cancer (NSCLC). Its use is specific to cancers with particular genetic characteristics.
If you miss a dose of Tagrisso, you should take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, you should skip the missed dose entirely. Do not take two doses at the same time to make up for a missed one. Continue with your regular dosing schedule the next day. Always consult your doctor if you are unsure.
Tagrisso is typically taken for as long as it is effectively controlling the cancer and the side effects are manageable. For some, this may be many months or even years. Your oncologist will monitor your response to the drug through regular scans and check-ups. The duration of treatment is a personalized decision made between you and your doctor based on your specific health situation and response to the therapy.
Tagrisso can potentially cause heart-related side effects, including a condition called QTc interval prolongation, which affects the heart's electrical rhythm. It can also, in some cases, weaken the heart muscle, a condition known as cardiomyopathy. Your doctor will likely monitor your heart function with an electrocardiogram (ECG) and other tests before and during your treatment to manage these risks. Inform your doctor if you feel dizzy or have fainting spells.
Tagrisso carries a risk of a serious lung condition called interstitial lung disease (ILD) or pneumonitis. You should contact your doctor immediately if you develop any new or worsening lung symptoms. These warning signs include sudden difficulty breathing or shortness of breath, a persistent cough that is new or different, or the development of a fever. Early diagnosis and treatment are critical for managing this potential side effect.
Tagrisso can interact with several other medications, which may alter its effectiveness or increase your risk of side effects. It is very important to tell your doctor about all medicines you take, including prescriptions, over-the-counter drugs, vitamins, and herbal supplements. Specifically, strong CYP3A4 inducers (like St. John's Wort) or inhibitors (like certain antibiotics) can significantly affect Tagrisso levels in your body. Your doctor may need to adjust your dosages accordingly.
You should avoid eating grapefruit or drinking grapefruit juice while taking Tagrisso. Grapefruit is a known inhibitor of the CYP3A4 enzyme in the liver. This enzyme is responsible for breaking down Tagrisso. Consuming grapefruit can increase the levels of the drug in your body, which could lead to a higher risk of experiencing serious side effects. Always check with your pharmacist or doctor about other potential food-drug interactions.
Tagrisso tablets should be stored at room temperature, which is typically between 68°F to 77°F (20°C to 25°C). Keep the medication in its original container with the lid tightly closed to protect it from moisture and light. Do not store it in a bathroom or other damp area. As with all medications, keep Tagrisso out of the reach of children and pets to prevent accidental ingestion.
Tagrisso can cause harm to an unborn baby, so it is not recommended for use during pregnancy. Women who are able to become pregnant should use effective birth control during treatment and for at least 6 weeks after the final dose. It is also advised not to breastfeed during treatment and for 2 weeks after the last dose, as the drug may pass into breast milk.
Tagrisso is designed to treat non-small-cell lung cancer, not to cure it. As a targeted therapy, it can be very effective at slowing the growth of cancer cells and shrinking tumors, which can extend life and improve its quality. For some patients in early stages, it can be used after surgery to reduce the risk of recurrence. However, cancer may eventually develop resistance to the drug.
Tagrisso tablets should ideally be swallowed whole with water. However, if you cannot swallow the tablet, it can be dispersed in 2 ounces (60 mL) of non-carbonated water. Stir the tablet in the water until it breaks into small pieces (it will not dissolve completely) and drink it immediately. Do not crush, chew, or heat the tablet. Rinse the glass with more water and drink to ensure you take the full dose.
Tagrisso commonly causes skin-related side effects. These can include a dry, itchy rash that may look like acne, as well as redness, tenderness, or infection in the skin around the fingernails and toenails. Most of these skin issues are mild to moderate and can be managed with lotions, creams, or other medications prescribed by your doctor. Inform your healthcare provider about any skin changes you experience.
Your doctor will determine if Tagrisso is working by performing regular evaluations. This typically involves imaging tests like CT scans or PET scans every few months to measure the size of the tumors and see if they have shrunk or stopped growing. They will also monitor your symptoms and overall health to assess your response to the treatment and ensure the medication is providing a benefit.
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