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  • US Name:


  • Generic Names:


  • Active Ingredients:

    Prucalopride as succinate

  • Brand Manufacturer:

    Janssen Cilag

  • Manufacturer Location:


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Prescription Required

Prudac / Resolor is a laxative that improves intestinal motility. It is used to treat constipation and restore the normal functioning of the bowel.

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Resolor Brand 2mg
28 Tablets
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28 Tablets
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Prudac / Resolor (generic name: prucalopride) is an oral medication used to treat adults diagnosed with chronic idiopathic or opioid-induced constipation. It belongs to the group of drugs called high-affinity 5-HT receptor agonist laxatives. It works by improving intestinal motility. Prucalopride acts on the muscles in the walls of the bowels. It improves the contractions of these muscles, thus improving the intestinal motility. This eases the passage of stools, providing relief from constipation. Prudac also helps to restore the normal functioning of the bowels and provides symptomatic relief from chronic constipation. Resolor is usually prescribed to adults for whom previous treatments with other laxatives failed to produce the desired results.


The dose and regimen are determined by the prescribing healthcare provider. The usual recommended dosage of Prudac is one 2 mg tablet once a day. For patients above 65 years of age and those suffering from severe hepatic impairment, the initial dose may be 1 mg tablet daily, which the prescribing doctor may increase subsequently.


Prudac is not recommended for use during pregnancy.  Women should inform their doctor if they are pregnant or planning to become pregnant. They are also advised to use a reliable contraceptive to prevent pregnancy while using this drug. Prucalopride, Prudac’s active ingredient, can pass into breast milk. For this reason, it is usually not recommended to breastfeed during treatment with Prudac.


Prudac tablets must be stored in the supplied blister packaging below 30°C and without direct exposure to heat, moisture, and sunlight. It should be kept away from the reach of children and pets to avoid accidental ingestion and poisoning. Any unused medication must be discarded safely after its expiration date is mentioned on the package.


What should be done in the case of Prudac’s overdosage? Overdosage of Prudac may result in loose bowel motions, headache, and nausea. Patients should seek appropriate treatment and increase their water intake in case of loose motions to avoid dehydration. Can you stop taking Prudac? Patients should not stop taking Prudac abruptly as it may cause the symptoms of constipation to return. Adhere to the treatment regimen recommended until consulting with a doctor. What are the differences between constipation and idiopathic constipation? Functional constipation has be apparent causes, such as the side effects of other medications or some conditions in the gut. On the other hand, idiopathic constipation lacks any clear physiological or anatomical explanation for the persistent discomfort and irregularity in bowel movements.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.

Read the information leaflet that comes with the medication.

Resolor may cause serious side effects, including unusual changes in mood or behavior, thoughts of self-harm, or suicide. In such a case, stop taking Resolor immediately and consult with a doctor as soon as possible.

Most people who use Prudac do not experience any negative side effects. Doctors prescribe Prudac because they assess that the benefits that such treatment yields outweigh any likely unwanted effects.

Some common side effects of Prudac include:

  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Abnormal bowel sounds
  • Indigestion
  • Flatulence
  • Dizziness
  • Tiredness

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Prudac is indicated for the management of constipation. It helps to improve bowel movements by stimulating the muscles in the walls of the intestine. This helps to increase intestinal motility, thereby supporting the passage of stool.

  • What precautions should be taken while using Prudac?
    Before treatment with Prudac, patients must inform the doctor if they suffer from severe kidney disease, inflammatory bowel disease, or hepatic impairment.
  • Is Prudac safe to use for children?
    Prudac is meant to treat constipation only in adults. It should not be given to children younger than 18 years of age.
  • Is it safe to use Prudac during pregnancy or breastfeeding?
    Prudac is not recommended for use during pregnancy. Women should inform the doctor if they are pregnant or planning to become pregnant. They are also advised to use a reliable contraceptive to prevent pregnancy while using this drug. The active ingredient of Prudac, prucalopride, can pass into breast milk. For this reason, it is not recommended to breastfeed during the course of treatment with Prudac.

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